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22  DIGESTIVE HEALTH




                                        THE NEXIUM CONTROL RANGE


                     Format/count       7s tablets             14s tablets      14s capsules    28s tablets
                     Patient need       New to PPIs            New to PPIs      Easy to swallow  Value for recurrent
                                                               looking for value                sufferers








                     Active ingredient                                  Esomeprazole
                     Pack size role     Trial pack               Complete 14-day   Complete 14-day     Value & convenience
                                          Start here for those using   treatment pack  treatment pack    For recurrent sufferers
                                        PPIs for the first time
                                          1 week supply                                         Exclusive to pharmacy

                               ADVICE FOR PATIENTS WITH FREQUENT HEARTBURN



                                              DO                                     DON'T


                                Eat smaller, more frequent meals         Have food or drink which triggers
                                                                       symptoms
                                Raise one end of your bed 10-20cm –
                               your chest and head should be above       Do not eat within 3 to 4 hours of bed
                               the level of your waist, so acid does
                               not travel up into your throat            Do not wear tight clothes around
                                                                       your waist
                                Try to lose weight if you are overweight
                                                                          Do not smoke or drink too much alcohol
                                Try to find ways to relax
                                                                         Do not stop taking any prescribed
                                Consider giving up smoking             medicines before speaking to a
                                                                       doctor first






                                                            DISCOVER THE SCIENCE
                                                            OF NEXIUM CONTROL





                    References: 1. Yamasaki T, et al. JNM Journal. 2018; 24(4). 2. Heartburn and acid reflux. NHS. Available at https://www.nhs.uk/conditions/heartburn-
                    and-acid-reflux/.  Accessed  September  2024.  3.  House  of  Commons  Library.  The  UK’s  changing  population.  July  2024.  Available  at:  https://
                    commonslibrary.parliament.uk/the-uks-changing-population.  Accessed  September  2024.  4.  Gov.uk.  Obesity  Profile:  short  statistical  commentary
                    May  2024.  Available  at:  https://www.gov.uk/government/statistics/update-to-the-obesity-profile-on-fingertips/obesity-profile-short-statistical-
                    commentary-may-2024 . Accessed September 2024. 5. IRI all outlets including chemists 52 w/e 31/8/24 6. Farup C et al. Arch Intern Med. 2001;161:45-
                    52. 7. Kulig M et al. Aliment Pharmacol Ther. 2003;18:767-76. 8. Ware JE Jr, Sherbourne CD. Med Care. 1992;30:473-83. 9. Heartburn and Acid Reflux.
                    Guts  UK!  https://gutscharity.org.uk/advice-and-information/symptoms/heartburn-and-reflux/.  10.  Sweis  R,  Fox  M.  The  global  burden  of  gastro-
                    oesophageal reflux disease: more than just heartburn and regurgitation. Lancet Gastroenterol Hepatol. 2020 Jun;5(6):519-521.  11. Hsu M, Safadi AO,
                    Lui F. Physiology, Stomach. 2023 Jul 17. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan. b13 12. Salisbury BH, Terrell JM.
                    Antacids. [Updated 2022 Aug 15]. 13. Leiman DA, Riff BP, Morgan S, Metz DC, Falk GW, French B, Umscheid CA, Lewis JD. Alginate therapy is effective
                    treatment for GERD symptoms: a systematic review and meta-analysis. Dis Esophagus. 2017 May 1;30(5):1-9.  14. National Center for Biotechnology
                    Information (2023). PubChem Compound Summary for CID 9568614, Esomeprazole. Retrieved September 1, 2023 from https://pubchem.ncbi.nlm.
                    nih.gov/compound/Esomeprazole.  15.  NICE  guidelines,  CG184  Sept  2014.  16.  Chemist  &  Druggist  price  list.  May  2024.  17.  IRI  All  Outlets  GB  inc
                    Chemists, unit sales, L12 w/e 17.08.2024. 18. Lind et al. Alimentary Pharmacology and Therapeutics, 2000; 14:861-867. 19. Tonini M et al. (2001) Clinical
                    pharmacology and safety profile of esomeprazole, the first enantiomerically pure proton pump inhibitor; Digest liver Dis 2001;33:600-6.
                    Product information: Nexium Control 20 mg gastro-resistant tablets and Nexium Control 20mg gastro-resistant hard capsules. Active ingredient:
                    Esomeprazole Indications: The short-term treatment of reflux symptoms (e.g. heartburn and acid regurgitation) in adults. Legal category: GSL: 14s
                    capsules, 7s tablets, and 14s tablets P: 28s tablets. PL holder: Haleon UK Trading Limited, The Heights, Weybridge, Surrey, KT13 0NY, U.K.
                    Information about these products, including adverse reactions, precautions, contraindications, and method of use can be found at:
                    https://www.medicines.org.uk/emc/product/819/smpc, https://www.medicines.org.uk/emc/product/14465/smpc
                    https://www.medicines.org.uk/emc/product/3660/smpc
                    Trade marks are owned by or licensed to the Haleon group of companies. PM-GB-NEX-24-00037



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                  SM6073 2024_Wholesaler - Nexium 4 Pager - Numark 9 PRESS_READY.indd   4                     08/11/2024   17:33
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