Page 201 - Genomic Medicine in Emerging Economies

190 Index

Colombia (cont.) make outsourcing the available worldwide perspective, 134
poor health planning, insufficient option, 19 genomic medicine interventions, 146
training in, 50 novel biomedical informatics human papillomavirus testing,
population, 160 infrastructure and tools, 20 136–141
study of hereditary cancers/ online educational/training working group, 155
hereditary diffuse gastric resources, 21 Education, 14. See also Genomic
cancer, 54, 65 Pan-Asia Pacific Genome medical education
Congenital disorders, 49 Initiative, 21 Golden Helix Academy, 183
Cooperative Medical Scheme, 53 patient activation, 21 healthcare professionals, 175
Cost benefit analysis, 9 provide avenues for EMA-approved drugs, 150
Cost-effectiveness analysis (CEA), management/integration of Emerging economies, 2
133, 134 genomic data, 23 developing countries and, 3
CYP3A5 pharmacogenes, 147 public health programs, 20 investing in genomics, 3
CYP2C9 genotyping-guided set up regulatory frameworks, 22 Epigenomics, 11
coumarin, 134 sharing of genomic data among Epilepsy, 72
CYP2C9 pharmacogenes, 147 scientists, 23 ETHNOS software, 148, 149
CYP2C19 pharmacogenes, 147 train data scientists and provide Exome Aggregation Consortium, 76
CYP2D6 pharmacogenes, 147 access, 23 Expensive health technologies, 145
Cystic fibrosis, 111 to train genomics workforce
with expertise, 20 F
D use of genomics in, 4 Familial adenomatous polyposis,
DALYs. See Disability-adjusted life Africa, 5 34, 37
years (DALYs) Asia, 6 clinical and genetic features, 35
Developing countries, 3, 133 Latin America, 7–8 in Latin America
barriers to implementation of Diagnostic biomarkers, 8 mutational screening of APC
genomic medicine in, 16 Direct-to-consumer (DTC), 154 gene, 35–38
and emerging economies investing Disability-adjusted life years mutational screening of
in genomics, 3 (DALYs), 72, 133 MUTYH, 37
GDP to research, 3 Discovery Research Investigating MUTYH associated
genomic medicine, measures to Founder Population Traits polyposis, 36
facilitate implementation of, 17 (DRIFT) Consortium, 156 Fast-Second Winner model, 8
overcoming barriers to Disease prevention, 14 FDA-approved drugs, 150
implementing genomic DNA banks of criminology, 115 FINDbase database, 150
medicine, 19 DNA damages, 38 Forensic genetics, 105–116
access to up-to-date literature, 23 DNA fingerprinting analysis, 58
adopting emerging low-cost DNA methylation analyses, 89 G
technologies, 20 DNA microarray, 58 Genetic composition, 1
Asia-Pacific Bioinformatics DNA mutation and polymorphism Genetic diseases, 138
Network, 21 analysis, 58 Genetic material, 1
build public trust and DNA repair genes, 65 Genetics education, 146
confidence, 23 DNA sequencing, 38 health care professionals, 153
convince national DNA structure, 102 Genetic testing, 2
governments, 19 DruGeVar database, 150 reimbursement of, 9
education, 21 Drug-genomic marker Genetic variation, 1
establishing international combinations, 9 Genome-based knowledge, 13
collaboration, 24 DTC. See Direct-to-consumer (DTC) Genome informatics, 146, 147
establishment of centers working group, 149
of excellence, 20 E Genome literacy, 153
financing setting up of such Economic evaluation/cost- Genomic and phenotypic
facilities, 19 effectiveness analysis, 147 variations, 13
foster multidisciplinary allopurinol, 141 Genomic “discovery” research, 13
collaborations, 23 anticoagulation therapy, 134–138 Genomic infrastructure expensive, 10
Global Organization for antidepressants, 139 Genomic laboratory, 14
Bioinformatics Learning, developing/emerging countries Genomic medical education, 186
Education and Training, 21 European perspective, 136 CME-accredited, 176