Page 204 - Genomic Medicine in Emerging Economies

Index 193

S State-of-the-art infrastructure, 2 suboptimal health status
(SHS), 60
Schizophrenia (SZ), 72 Stevens-Johnson syndrome (SJS), 134 Transciptomics, 11
allopurinol-induced, 135
Senior National Representatives, 147 HLA-B*1502 and carbamazepine, Translational genomics, 13
SHSQ-25 self-reported survey 134 Treatments, ineffective, 1
tool, 61
Single Strand Conformation Suboptimal health status U
(SHS), 60, 61
Polymorphisms (SSCPs), 71
SJS. See Stevens-Johnson syndrome Sudden arrhythmia, 101 Ubiquitous Pharmacogenomics
Sudden death, 101
(SJS) Project (UPGx), 183
Skills, 14 Supply-induced demand Unhealthy lifestyle, 145
for services, 145
SLCO1B1 pharmacogenes, 147 United States Food and Drug
Sri Lanka T Administration (FDA), 101
challenges UPGx project, 185
for bioinformatics and TCM. See Traditional Chinese US Food and Drug
reporting, 17 Medicine (TCM) Administration, 183
in test pricing, 16 Three-dimensional maps, 13
clinical exome sequencing Toxic epidermal necrolysis V
(CES), 16 (TEN), 134 VKORC1 genotyping-guided
using TruSight One exon TPMT pharmacogenes, 147 coumarin, 134
enrichment technology, 16 Traditional Chinese Medicine VKORC1 pharmacogenes, 147
facilitate improved care for (TCM), 27, 40
patients, 18 application of genomics W
future plans for expanding efforts, technologies in, 35, 36
18 challenges and opportunities, 42 Warfarin, 134
genomic services, 15 chemotherapy-associated side WES. See Whole exome sequencing
to improved patient care, 16 effects relief, 60 (WES)
infrastructure and manpower, 15 elucidation of putative biological Whole exome sequencing
initial experience in implementing mechanisms of, 37 (WES), 13
genomic medicine, 15 genomics-informed clinical pharmacogenomic testing, 147
next-generation sequencing trials of, 62 World Health Organization
(NGS) services, 16 herbal formula of San Huang Xie (WHO), 49
using the Illumina MiSeq NGS Xin Tang (SHXXT), 58
platform and in-house integrating with modern medicine Y
bioinformatics pipeline, 16 at omics level, 43, 62 Years lived with disability (YLDs), 72