Page 141 - 00. Complete Version - Progress Report IPEN 2014-2016

Radiopharmacy | Progress Report 141

Figure 8 shows the Cyclone 18.

Clean Room

In the cyclotron facility, there is a clean room, class 10,000, with two double hot cells for syn-
thesis modules and a laminar flow hot cell for reception of the final product, as shown in Fig-
ure 9. The cells were acquired from Comecer-Italy. This clean room was constructed according
to regulations in radiation protection as well as to appropriate rules of working under aseptic
conditions (GMP).

Inside these hot cells synthesis modules are installed: two Synthera model, from Ion Beam
Applications (Figure 10a) and three TraceLab MX model from GE (Figure 10b). These synthesis
modules allow the routine production of 18F-FDG, 18F-NaF and experimental production of
another radiopharmaceutical labelled with 18F.