Page 21 - BRAND BOOK FIXAPROST
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Fixed combinations are recommended
in practice guidelines
• “when IOP is not sufficiently controlled by one single agent” recommandations EGS
• When adding a 2nd drug:
“Multiple topical treatments may jeopardize adherence, result in reduced
efficacy through wash-out of earlier medications with later medications
and increase exposure to preservatives”
• When limiting preservatives’ toxicity:
“therapeutic possibilities are the use of preservative-free or BAK-free medication,
decreasing the number of preserved eyedrops i.e. by using fixed combination;
treating the ocular surface with unpreserved tear substitutes”
The patient’s cooperation, described as adherence and
persistence, with the prescribed glaucoma management is
mandatory to obtain effective IOP lowering and to prevent
glaucoma progression. No drug can work unless it is taken.
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