Page 137 - Pharmacology Mnemonics and Short Notes

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Uses of nitroglycerine

A man has spasm

A  angina pectoris

Man  myocardial infection

Has  severe hypertension

Spasm  coronary artery spasm

Interactions

With sidenaphil

 Sidenaphil is used for Erectile dysfunction  act by inhibit

breakdown of cGMP  result inc of cGMP

 Nitrates  also inc cGMP by increase production by release of NO

 So Net effects produced by cGMP will be more marked

o And will result high level of hypotension

Cyanide poisoning

Cyanide + iron of cyt P450 complex is formed  oxidative
metabolism is blocked

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Pharmacology Mnemonics and Short Notes By Muhammad Ramzan Ul Rehman