Page 144 - Pharmacology Mnemonics and Short Notes

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 They are powerful depressants of Na current and they increase
QRS duration

Uses

Refractory arrhythmia

 Use is restricted to persistent arrhythmias fail to response other
therapies

Group 2. Beta Blockers

Prototype drugs propranolol and Esmolol

Mechanism

Beta adrenoreceptor
Beta blocker dec cAMP
blockage

reduce Na Ca
currents in reduce pace
abnormal pace maker acivity
maker

 AV nodes are selective to beta blockage

 PR interval is usually prolonged

 Amiodrone and sotalol are from group 3 but have some activity of

group 2

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Group 3. K channel blockers

Bachy parh nh rhay thy tu ami sota lai or sab ki kutt laga di

Ami  amiodrone
Contents Sota  sotalol

Pharmacology Mnemonics and Short Notes By Muhammad Ramzan Ul Rehman