Page 145 - Pharmacology Mnemonics and Short Notes

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Lai  lides ibutilide and dofetilide

Kutt  K channel blockers

Mechanism

+
Block K channel  result prolongation of action
potential and refractory period.

 Also show activity of other groups like sotalol also
blocks Beta blocker & amiodrone show activity of group 1 2 and
itself is 3 and of 4

Amiodrone

Most efficacious of all antiarrhythmic drugs

+
 Block Na channel
 Block beta adrenoreceptor

+
 Block K channel
+2
 Block Ca channel

Use is restricted why?

 Extensive toxic effects are produced  used only where other
drugs are not responding

Adverse effects

Micro ppts of amiodrone

Micro microcrystalline deposits

P  pulmonary fibrosis

P  paraesthesia

T  thyroid dysfunction

S  skin sensitivity to light
Contents Dronedrone

Pharmacology Mnemonics and Short Notes By Muhammad Ramzan Ul Rehman