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Effects (high lipid solubility and shorter duration of action)

 Respiratory and CNS depression

 Decrease ICP

Side effects

CNS depression extensions

Benzodiazepines

Midazolam, diazepam and lorazepam are used

Effects

 Less depression than barbiturates

 Shorter onset and longer duration of action than barbiturates

Side effects

 Respiratory depression

Dissociative  Ketamine

Block excitation by NMDA receptor

 NMDA  N methyl D aspartate

Effects

 Analgesia

 Amnesia

 Catatonia  neurogenic motor immobility

 CVS stimulation

Dissociative anaesthesia

Dissociative are a class of hallucinogen in which distort perceptions of
Contents sight and sound and produce feelings of detachment (dissociation) from
the environment and self.

Pharmacology Mnemonics and Short Notes By Muhammad Ramzan Ul Rehman