Page 251 - Pharmacology Mnemonics and Short Notes

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Ionic Mechanisms

Presynaptic membrane (all receptors)

 Decrease Ca influx  decrease neurotransmitter release

Postsynaptic membrane (mu receptor)

 Increase K conduction  inhibitory post synaptic potential develop
d

Members and classification

Strong agonists

Max effects  M  morphine, methadone and meperidine

Moderate agonists

Cods Codeine and oxycodone

Weak agonists

Propoxyphene  partial mean weak

Effects produced

Acute effects

BAD Americans

B  Bradycardias and hypotension

A  Analgesia

[treatment of moderate to severe pain]

D  Dependence

A  anorexia  poor appetite and
release of ADH hormone

M  miosis (characteristic of all opioids except meperidine)
Contents E  euphoria  state of excitement

Pharmacology Mnemonics and Short Notes By Muhammad Ramzan Ul Rehman