Page 96 - Pharmacology Mnemonics and Short Notes

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07. Prostaglandins and

other Eicosanoids

Pathways

 Lipoxigenase pathway L Leukotrienes

 Cyclooxygenase pathway  others all

o Prostaglandins

o Prostacyclin

o Thromboxane

Mechanism of action

Action are brought about by cell surface G protein coupled receptors

Some inhibitors to be remember

 Corticosteroids  Phospholipase A 2 (convert phospholipid

Arachidonic acid)

 NSAIDS  Inhibit COX (cyclooxygenase)

 ZeliutonZe + Li Ze indicate this is Zeliuton and Li indicate it is
lipoxygenase enzyme inhibitor

 Zafirlukastzafir+ LukoZafir indicated this is zafirlukast and
Leuko indicate that this ihibitLeukotriene receptor antagonist

 Montelukast Brother of zafirlukast

Effects Produced By Eicosanoids.

On Blood Vessels

Imagine a circle expanding

Circle  Prostacyclin (PGI 2)
Contents

Pharmacology Mnemonics and Short Notes By Muhammad Ramzan Ul Rehman