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VALP Valproate Specimen Requirements
Submit only one of the followings

Preferred Specimen Type: Serum Container/Tube: Gold Top (SSTII) / Red Top

Volume: 5.0mL / 6.0mL Minimum Volume: 0.5mL serum
Collection Instructions: Allow specimen to clot for 30 minutes and centrifuge

within 2 hours Acceptable Specimen Type: Plasma Container/Tube: Green Top

(Li Heparin/PST) Volume: 4.5mL Minimum Volume: 0.5mL plasma Collection
Instructions: Centrifuge within 2 hours Unacceptable Condition Haemolysis NA

Icterus NA Lipaemic NA Others NA Sample Stability **

Preferred temperatures for storage prior to and during shipping to NUH **
Specimen Type: Serum Ambient: 1 day Refrigerate: 2 weeks Frozen: 1 month

Reference Interval Therapeutic range 50 – 100 mg/L Toxic concentration > 200
mg/L Call back values: > 200 mg/L Days and Times Performed 24 hours,

TAT 1 day Testing Laboratory National University Hospital Clinical Chemistry,
67724346

Methodology Homogeneous enzyme immunoassay Useful For Therapeutic

drug monitoring Alias Valproic Acid Service Code 0031385 Update Last
updated 03/10/2016 Portions ©2020 Mayo Foundation for Medical Education

and Researc

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