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                   404 Chapter 9: Dermatology and soft tissues


                    Skin and soft tissue lumps                  Aetiology/pathophysiology
                                                                Solar keratoses are seen in fair-skinned patients asso-
                                                                ciated with sun exposure. They are most common in
                   Seborrhoeic keratoses                        patients who burn easily and tan poorly. There is debate

                   Definition                                    as to whether solar keratoses leads to squamous cell car-
                   Seborrhoeic keratoses are a benign localised prolifera-  cinoma, or whether squamous cell carcinomas arise in
                   tion of the basal layer of the epidermis. They are some-  the same areas due to the sun damage.
                   times termed basal cell papillomas; however, they are not
                   neoplastic and are not premalignant.         Clinical features
                                                                Lesions initially appear as a small, well-demarcated, red
                   Incidence                                    brown plaque that progress to become more erythema-
                   Common; by age 40 approximately 10% of individuals  tousandhyperkeratotic.Solarkeratosesbleedeasilywith
                   have one seborrhoeic keratosis.              minor trauma.

                   Age                                          Management
                   Increase in incidence with increasing age.   Treatment includes cryotherapy, curettage or topical
                                                                5-fluorouracil.
                   Sex
                   M = F
                                                                Dermatofibromas
                   Aetiology/pathophysiology                    Definition
                   The cause of seborrhoeic keratoses is unclear, although  Adermatofibroma is a cutaneous nodule containing
                   they occur more commonly on sun-exposed skin.  macrophages or histiocytes.

                   Clinical features                            Incidence
                   Lesions occur most commonly on the trunk. They are  Common.
                   flat, raised or pedunculated with a yellow brown ap-
                   pearance of the overlying skin. With time the surface  Age
                   becomes irregular and wart-like. Lesions may cause con-  Can occur at any age, more common in adults.
                   cern due to bleeding, itching or surrounding inflamma-
                   tion.
                                                                Sex
                                                                4F:1M
                   Management
                   If treatment is required, cryotherapy or currettage are
                                                                Aetiology/pathophysiology
                   usually effective.
                                                                Historically dermatofibromas have been associated with
                                                                trauma or insect bites, although the cause is unknown.
                   Solar keratoses

                   Definition                                    Clinical features
                   Solar keratoses or actinic keratoses are single, small scaly  Lesions occur most commonly on the lower limbs. They
                   plaques occuring as a result of sun damage to the skin.  are solitary firm elevated nodules with pigmentation of
                                                                the overlying skin. Although classically asymptomatic
                   Incidence                                    they may cause itching or pain.
                   Common.
                                                                Management
                   Age                                          Dermatofibromas are removed only if troublesome or if
                   Occurs in the middle-aged and elderly.       there is diagnostic uncertainty.
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