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‘Nadat Coen Hemker rector magnificus was geweest en hij Suzette Béguin naar Maastricht haalde, nam Hemker zich voor: “Ik ga weer kijken in het plas- ma”. Wíj vonden dat overigens absoluut niet zo’n goed idee. Wij waren juist zo ver dat we alle afzonderlijke eiwitten begonnen te begrijpen en toen begon Coen weer te werken aan die plasmasoep. Dat leek een stap terug.’
Jan Rosing (2013)1
‘I felt that, as far as pure biochemistry was concerned, I could, at the best, do as good as my collaborators did. As an MD, I also felt that we were drifting too far from our medical roots and that “the patient” had disappeared over the horizon. That is why I was so eager to implement the pathophysiological ap- proach, i.e. looking at the “isolated organ” plasma rather than at its purified constituents. In fact it is not a question of either or, the two approaches are supplementary.’
H.Coen Hemker (2014)2
Nobel Prize Chemistry 1978, awarded to Peter Mitchell for his contribution to the understanding of biological energy transfer through the formulation of the chemiosmotic theory
‘At this stage, in 1961, Peter Mitchell put forward his chemiosmotic hypo- thesis. The basic idea of this hypothesis is that the enzymes of the electron- transport and ATP-synthesizing systems are localized in the membrane with a well-defined orientation and are functionally linked to a vectorial transfer of positively charged hydrogen ions, or protons, across the membrane. ... The chemiosmotic hypothesis was received with reservation by many workers in the field which is, in a way, understandable, since it was unorthodox, fairly provocative, and based on little experimental evidence.’
Lars Ernster [Swedish Royal Academy of Sciences] (1978)3