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A28    SCIENCE
                Tuesday 10 december 2019
            Brain differences may be tied to obesity, kids’ study says




            By LINDSEY TANNER                                                                                                   weight  and  Mackey  said
            AP Medical Writer                                                                                                   it’s  likely  other  factors  not
            New results  from the larg-                                                                                         measured  in  the  study  in-
            est  long-term  study  of                                                                                           cluding  physical  activity
            brain  development  and                                                                                             and  healthy  nutrition  play
            children’s health raise pro-                                                                                        a far greater role.
            vocative  questions  about                                                                                          Research  in  adults  has
            obesity and brain function.                                                                                         linked obesity with low-lev-
            Does  excess  body  weight                                                                                          el inflammation throughout
            somehow  reduce  brain                                                                                              the  body  that  can  dam-
            regions that regulate plan-                                                                                         age  blood  vessels  and
            ning  and  impulse  control?                                                                                        may increase risks for heart
            Is  obesity  a  result  of  that                                                                                    disease  and  mental  de-
            brain  difference?  Or  are                                                                                         cline.  Some  studies  have
            eating habits, lifestyle, fam-                                                                                      also  found  less  brain  vol-
            ily  circumstances  and  ge-                                                                                        ume  in  obese  adults  and
            netics to blame?                                                                                                    researchers theorize that it
            Previous studies in children                                                                                        could  be  from  inflamma-
            and adults have had con-                                                                                            tion.
            flicting results. The new re-                                                                                       The  new  study  raises  the
            search  doesn’t  settle  the                                                                                        possibility  that  inflamma-
            matter and outside experts   In this July 23, 2009 file photo, children are silhouetted by the setting sun as they ride a swing ride   tory  changes  affecting
            cautioned  that  misinter-   during the Canyon County Fair in Caldwell, Idaho.                                      weight, brain structure and
            preting  it  could  unfairly                                                                       Associated Press   function  might  begin  in
            perpetuate weight stigma.                                                                                           childhood.
            But  an  editorial  published   national statistics.      handle multiple tasks simul-  executive  function.  But   The  latest  research  con-
            with  the  study  Monday  in   Researchers  found  differ-  taneously.                 Mackey  and  lead  author    firms  previous  studies  in
            JAMA  Pediatrics  called  it   ences in the heaviest chil-   The differences compared   Jennifer  Laurent,  a  Univer-  children  and  adults,  but
            an  important  addition  to   dren’s  brain  scans,  slightly   with  normal-weight  kids   sity of Vermont obesity re-  it  leaves  many  questions
            mounting  evidence  of  a    less  volume  in  the  brain   were subtle, said study au-  searcher, said it’s unknown   unanswered,  said  Marci
            link between weight, brain   region  behind  the  fore-   thor Scott Mackey, a neu-    whether  any  of  the  differ-  Gluck,  a  research  psy-
            structure and mental func-   head  that  controls  what   roscientist at the University   ences had any meaningful   chologist  at  the  National
            tion.                        are  known  as  “executive   of Vermont.                  effect  on  children’s  aca-  Institute  of  Diabetes  and
            If  follow-up  research  con-  function”  tasks.  They  in-  The heaviest kids also had   demic  functioning  or  be-  Digestive  and  Kidney  Dis-
            firms  the  findings,  it  could   clude  things  like  ability  to   slightly  worse  scores  on   havior. It’s unclear exactly   eases, who was not part of
            lead  to  new  ways  to  pre-  plan, control impulses and   computer-based  tests  of   how  they  are  related  to   the research. q
            vent obesity that target im-
            proved brain function.
            “We don’t know which di-                                  SpaceX delivers ‘mighty mice,’
            rection  these  relationships
            go  nor  do  they  suggest                                worms, robot to space station
            that  people  with  obesity
            are not as smart as people
            at  a  healthy  weight,”said                              By MARCIA DUNN               It marks the third visit for this   Cimon,  it’s  an  improved
                                                                      AP Aerospace Writer
                                                                                                                                version  of  what  flew  up
                                                                                                   recycled Dragon.
            Dr.  Eliana  Perrin,  a  Duke
            University pediatrics profes-                             CAPE  CANAVERAL,  Fla.       Flight controllers quickly se-  last  year  to  be  tested  as
                                                                                                                                an astronaut’s helper.
                                                                      (AP)  —  SpaceX  made  an
                                                                                                   cured  the  capsule  to  the
            sor  who  co-wrote  the  edi-
            torial.                                                   early  holiday  delivery  to   orbiting  lab,  paving  the   NASA  has  tucked  some
                                                                                                                                Christmas  presents  in  the
                                                                                                   way for the hatch to open
                                                                      the  International  Space
            The federally-funded study
            involved 3,190 U.S. children                              Station  on  Sunday,  bring-  and  the  unloading  to  be-  shipment  for  the  station’s
                                                                      ing muscle-bound  “mighty
                                                                                                   gin.
                                                                                                                                six-person crew, as well.
            aged  9  and  10.  They  had
            height  and  weight  mea-                                 mice,”  pest-killing  worms   The  capsule  holds  3  tons   It’s SpaceX’s 19th delivery
                                                                                                   (2,720  kilograms)  of  sup-
                                                                                                                                to the orbiting outpost for
                                                                      and  a  smart,  empathetic
            surements, MRI brain scans
            and computer-based tests                                  robot.                       plies, including 40 mice for   NASA over the past seven
                                                                                                                                years.
                                                                                                   a muscle and bone experi-
                                                                      The  station  commander,
            of  mental  function  includ-  In  this  image  provided  by
            ing  memory,  language,       NASA,  the  SpaceX  Dragon   Italy’s   Luca   Parmitano,   ment. Eight of them are ge-  The  astronauts  have  an-
                                                                                                                                        shipment
                                                                                                   netically  engineered  with
                                                                      used  a  large  robot  arm
                                                                                                                                                    com-
                                                                                                                                other
            reasoning    and   impulse    capsule   arrives   at   the
            control. Nearly 1,000 kids —   International  Space  Station,   to  grab  onto  the  Dragon   twice  the  normal  muscle   ing  Monday  —  this  one
                                                                      three days after its launch
                                                                                                                                launched  by  Russia  from
                                                                                                   mass — and so are consid-
            almost 1 in 3 — were over-    Sunday, Dec. 8, 2019.
            weight or obese, similar to              Associated Press  from Cape Canaveral. The    ered “mighty mice.”’         Kazakhstan on Friday.q
                                                                      two  spacecraft  soared      There  also  are  120,000
                                                                      260  miles  (420  kilometers)   roundworms,   or   nema-
                                                                      above the South Pacific at   todes  of  a  beneficial  va-
                                                                      the time of capture.         riety  that  are  part  of  an
                                                                      “Whenever  we  welcome       agricultural study aimed at
                                                                      a  new  vehicle  on  board,   controlling  pests  here  on
                                                                      we  take  on  board  also  a   Earth.
                                                                      little  bit  of  the  soul  of  ev-  The  capsule  also  has  a
                                                                      erybody  that  contributed   large,  round  robot  head
                                                                      to the project, so welcome   with  artificial  intelligence
                                                                      on board,” Parmitano told    and the ability to sense as-
                                                                      Mission Control.             tronauts’ emotions. Named
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