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A28    SCIENCE
                    Tuesday 10 april 2018

            Studies link legal marijuana with fewer opioid prescriptions



            By MALCOLM RITTER                                                                                                   to  other  findings  that  sug-
            NEW YORK (AP) — Can le-                                                                                             gest  to  experts  that  mari-
            galizing marijuana fight the                                                                                        juana is a viable alternative
            problem  of  opioid  addic-                                                                                         to  opioids.  The  weight  of
            tion  and  fatal  overdoses?                                                                                        that evidence is "now hard
            Two new studies in the de-                                                                                          to  ignore,"  said  Bradford,
            bate suggest it may.                                                                                                who  said  he  thinks  fed-
            Pot  can  relieve  chronic                                                                                          eral  regulations  should  be
            pain  in  adults,  so  advo-                                                                                        changed  to  allow  doctors
            cates  for  liberalizing  mari-                                                                                     to  prescribe  marijuana  for
            juana laws have proposed                                                                                            pain treatment.
            it as a lower-risk alternative                                                                                      The two studies have some
            to  opioids.  But  some  re-                                                                                        limitations,  Dr.  Kevin  Hill  of
            search  suggests  marijuana                                                                                         Harvard  Medical  School
            may  encourage  opioid                                                                                              and  Dr.  Andrew  Saxon  of
            use, and so might make the                                                                                          the  University  of  Washing-
            epidemic worse.                                                                                                     ton  in  Seattle  wrote  in  an
            The  new  studies  don't  di-                                                                                       accompanying editorial.
            rectly  assess  the  effect  of                                                                                     For  one  thing,  they  don't
            legalizing  marijuana  on                                                                                           reveal  whether  individual
            opioid addiction and over-                                                                                          patients  actually  reduced
            dose deaths. Instead, they                                                                                          or  avoided  using  opioids
            find evidence that legaliza-  In this Thursday, Feb. 15, 2018 file photo, a woman holds the prescribed medical marijuana prod-  because  of  the  increased
            tion  may  reduce  the  pre-  uct used to treat her daughter's epilepsy after making a purchase at a medical marijuana dis-  access  to  marijuana.  The
            scribing  of  opioids.  Over-  pensary in Butler, Pa.                                                               findings  in  Medicaid  and
            prescribing  is  considered                                                                        Associated Press  Medicare patients may not
            a  key  factor  in  the  opioid                                                                                     apply to other people. And
            epidemic.                    gest  the  medical  marijua-  them to grow pot at home  economist at the University  the results may have been
            Both studies were released  na laws didn't reach some  showed  about  7  percent  of Georgia in Athens who's  skewed  by  some  charac-
            Monday  by  the  journal  people  who  could  benefit  fewer doses.                    an  author  of  the  second  teristics of the state popula-
            JAMA Internal Medicine.      from  using  marijuana  in-  W.  David  Bradford,  an  study,  said  the  results  add  tions studied, they wrote.q
            One  looked  at  trends  in  stead  of  opioids,  said  He-
            opioid  prescribing  under  fei Wen of the University of
            Medicaid,    which    cov-   Kentucky in Lexington, one   Fossil finger points to early
            ers   low-income    adults,  of the study authors.
            between  2011  and  2016.  The  other  study  looked  at
            It  compared  the  states  opioid  prescribing  nation-   humans entering Saudi Arabia
            where marijuana laws took  wide for people using Medi-
            effect versus states without  care, which covers people
            such laws. The comparison  65 years or older and those                                                              By MALCOLM RITTER
            was done each quarter, so  with  disabilities.  Every  year                                                         NEW  YORK  (AP)  —  An  an-
            a given state without a law  from 2010 through 2015, re-                                                            cient  human  finger  bone
            at one point could join the  searchers compared states                                                              found in Saudi Arabia pro-
            other category once a law  with  a  medical  marijuana                                                              vides  a  new  clue  about
            kicked  in.  Results  showed  law in effect to those with-                                                          when and how our species
            that  laws  that  let  people  out  one.  Fourteen  states                                                          migrated out of Africa.
            use marijuana to treat spe-  plus  the  District  of  Colum-                                                        Researchers  say  it  shows
            cific  medical  conditions  bia  had  such  a  law  from                                                            hunter-gatherers      had
            were associated with about  the beginning of that time;                                                             reached  that  area  by
            a  6  percent  lower  rate  of  nine  other  states  joined                                                         85,000 years ago. Previous-
            opioid prescribing for pain.  them  during  the  years  the                                                         ly  discovered  human  fos-
            That's  about  39  fewer  pre-  study covered.                                                                      sils show an earlier human
            scriptions per 1,000 people  Researchers  found  that                                                               presence in Israel and pos-
            using Medicaid.              Medicare patients in states                                                            sibly China.
            And when states with such  with marijuana dispensaries                                                              Scientists   believe   early
            a  law  went  on  to  also  al-  filled prescriptions for about                                                     people  left  Africa  more
            low recreational marijuana  14 percent fewer daily dos-                                                             than  once  after  evolving
            use by adults, there was an  es  of  opioids  than  those   This  photo  provided  by  Michael  Petraglia  shows  six  different   there at least 300,000 years
            additional  drop  averaging  in  other  states.  Patients  in   views of a Homo sapiens fossil finger bone from the Al Wusta   ago.
            about 6 percent. That sug-   states  that  only  allowed   archaeological site in Saudi Arabia.                     The  bone,  from  an  adult
                                                                                                               Associated Press  and  most  likely  a  middle
                                                                                                                                finger,  was  found  in  2016
                                                                                                                                about  340  miles  (550  kilo-
                                                                                                                                meters)  southeast  of  the
                                                                                                                                Sinai  Peninsula.  Michael
                                                                                                                                Petraglia   (peh-TRAH-lee-
                                                                                                                                uh)  of  the  Max  Planck  In-
                                                                                                                                stitute  for  the  Science  of
                                                                                                                                Human  History  in  Jena,
                                                                                                                                Germany, says the ancient
                                                                                                                                people probably left Africa
                                                                                                                                through the peninsula.q
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