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A12   HEALTH
                Thursday 22 OcTOber 2020
            Next up in hunt for COVID-19 vaccine: Testing shots in kids




            By LAURAN NEERGAARD                                                                                                 ers.  In  a  letter  to  federal
            AP Medical Writer                                                                                                   health  officials,  the  AAP
            The global hunt for a COV-                                                                                          cited recent evidence that
            ID-19 vaccine for kids is only                                                                                      those  over  age  10  may
            just beginning — a lagging                                                                                          spread the virus just as eas-
            start  that  has  some  U.S.                                                                                        ily as adults do.Add missing
            pediatricians  worried  they                                                                                        school  and  other  factors
            may  not know if any shots                                                                                          unique to children, and it's
            work  for  young  children                                                                                          unethical "to allow children
            in  time  for  the  next  school                                                                                    to  take  on  great  burdens
            year.  Older  adults  may                                                                                           during  this  pandemic  but
            be  most  vulnerable  to  the                                                                                       not  have  the  opportunity
            coronavirus, but ending the                                                                                         to benefit from a vaccine,"
            pandemic will require vac-                                                                                          Dr. Sara Goza, president of
            cinating children, too. Last                                                                                        the  pediatrics  academy,
            week,  Pfizer  Inc.  received                                                                                       wrote.
            permission  to  test  its  vac-                                                                                     Globally,  pediatric  studies
            cine in U.S. kids as young as                                                                                       are  only  hesitantly  emerg-
            12, one of only a handful of                                                                                        ing. In China, Sinovac and
            attempts around the world                                                                                           SinoPharm  have  opened
            to start exploring if any ex-                                                                                       studies  that  can  test  chil-
            perimental    shots   being                                                                                         dren as young as 3.
            pushed for adults also can                                                                                          A British study of a vaccine
            protect children.                                                                                                   by  AstraZeneca  allows  for
            "I just figured the more peo-                                                                                       testing  of  a  low  dose  in
            ple they have to do tests on,                                                                                       certain  children  but  the
            the  quicker  they  can  put   In  this  photo  provided  by  Cincinnati  Children’s  Hospital  Medical  Center,  clinical  research   company  says  it  won't  be
                                         coordinator Tammy Lewis-McCauley administers an injection to Katelyn Evans, a trial participant,
            out a vaccine and people     as part of the hospital’s clinical trial of Pfizer's COVID-19 vaccine at Cincinnati Children’s Hospital   recruiting youngsters until it
            can  be  safe  and  healthy,"   Medical Center on Wednesday, Oct. 14, 2020.                                         has  "sufficient"  safety  data
            said 16-year-old Katelyn Ev-                                                                       Associated Press   in adults.
            ans,  who  became  the  first                                                                                       In  the  U.S.,  Moderna  Inc.,
            teen to get an injection in  dren.  Vaccines  can't  be  study  in  adolescents,  he  many U.S. children die from  Johnson  &  Johnson  and
            the  Pfizer  study  at  Cincin-  given  to  youngsters  unless  finds  it  "very  concerning"  flu in an average year. Ad-  Novavax all hope to begin
            nati Children's Hospital.    they've been tested in their  that children younger than  ditionally,  a  small  number  some  pediatric  research
            Multiple  vaccine  candi-    age group -- a major hurdle  12 may not have a vaccine  have  developed  a  serious  later in the year, in varying
            dates  are  in  final-stage  in efforts to reopen schools  by next fall.               inflammatory     condition  age groups.
            studies in tens of thousands  and  resume  more  normal  Children  represent  about  linked to the coronavirus.     "If  we  immunize  adoles-
            of adults, and scientists are  activities that are critical to  10%  of  COVID-19  cases  Overall, Anderson says CO-  cents  --  and  potentially
            hopeful  that  the  next  few  families' well-being.      documented  in  the  U.S.  VID-19's impact on children  move  down  into  younger
            months will bring evidence  "The  public  doesn't  under-  And  while  children  are  far  is greater than some other  children  --  we're  going  to
            that at least some of them  stand  that,"  said  Dr.  Evan  less likely than adults to get  diseases  that  require  rou-  have the effect of keeping
            are  safe  and  effective  Anderson  of  Emory  Univer-   seriously ill, about 120 have  tine pediatric vaccinations.  those  children  from  get-
            enough  for  widespread  sity,  who  has  been  push-     died  in  the  U.S.  alone,  ac-  Aside from their own health  ting infected. But then also
            use. But when the first shots  ing  for  pediatric  testing  of  cording  to  a  tally  by  the  risks  is  the  still  unanswered  they  don't  bring  the  infec-
            arrive,  they're  unlikely  to  COVID-19  vaccines.  While  American Academy of Pe-    question  about  how  eas-   tion  home  to  parents  and
            be recommended for chil-     he's encouraged by Pfizer's  diatrics.  That's  about  how  ily  children  can  infect  oth-  grandparents," he said.q


              What are the treatment options for COVID-19?



                                                                      which one is best depends  Here's  what's  advised  for  survivor that contains anti-
                                                                      on how sick someone is.     various patients:           bodies that fight the virus?
                                                                      For example, steroids such  --  Not  hospitalized  or  hos-  Not  enough  is  known  to
                                                                      as  dexamethasone  can  pitalized  but  not  needing  recommend for or against
                                                                      lower  the  risk  of  dying  for  extra  oxygen:  No  specific  it, the guidelines say.
                                                                      severely  ill  patients.  But  drugs recommended, and  However, enough is known
                                                                      they  may  do  the  oppo-   a  warning  against  using  to advise against hydroxy-
                                                                      site for those who are only  steroids.                  chloroquine  and  certain
                                                                      mildly ill.                 --  Hospitalized  and  need-  drugs  that  affect  the  im-
                                                                      In  the  United  States,  no  ing  extra  oxygen  but  not  mune  system  --  multiple
                                                                      treatments are specifically  a breathing machine: The  studies  have  found  them
                                                                      approved  for  COVID-19,  antiviral  drug  remdesivir,  ineffective  against  the
                                                                      but a few have been au-     given  through  an  IV,  and  coronavirus.
                                                                      thorized  for  emergency  in  some  cases  also  a  ste-  Aside  from  drugs,  doctors
                                                                      use and several more are  roid.                         have learned more about
              A  nurse  collects  a  sample  on  a  patient  at  a  drive-thru   being considered.   --  Hospitalized  and  on  a  ways  to  treat  hospital-
              COVID-19 clinic in Montreal, Wednesday, Oct. 21, 2020.  A  panel  of  experts  con-  breathing  machine:  Rem-  ized patients, such as put-
                                                     Associated Press   vened by the National In-  desivir and a steroid.     ting  them  on  their  bellies
                                                                      stitutes  of  Health  updates  What  about  convales-   and  other  measures  that
              By The Associated Press     options for COVID-19?       guidelines  as new studies  cent  plasma,  an  infusion  may prevent the need for
              What  are  the  treatment  There  are  several,  and    come out.                   of blood from a COVID-19  breathing machines. q
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