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Glucose-lowering Potential of Diabetes Therapies
Medications (brand) FPG ↓ A1C ↓
Sulfonylureas (Amaryl, Glyburide) 50-60 mg/dl 1-2%
Metformin (Glucophage) 50-60 mg/dl 1-2%
α-Glucosidase Inhibitors/AGI(Precose) 15-30 mg/dl 0.5-1%
Repaglinade (Prandin/Starlix) 60mg/dl 1.7%
Thiazolidinediones/TZD (Actos) 40-60 mg/dl 1-2%
DDP4 Inhibitors (Januvia, Onglyza) targets ppd 0.5 - 0.8%
SGLT2 Inhibitors (Invokana, Frexiga) 25 – 55 mg/dl 0.9 – 1.1%
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