Page 8 - 2018-2019 ARCS Oregon Annual Report

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“My dissertation project stems from the novel observation that breast cancer liver metastases
are are ~3x more common in in women diagnosed within 10 years of a a a a a a a a a pregnancy compared to never pregnant women We think this means that there is is something unique about the the liver environment in in a a a a a a a a a a a postpartum woman that promotes breast cancer metastasis I I use use mouse and human human liver liver metastases
as as as as as as well as as as as as as human human liver liver MR Imaging data to study the the hypothesis that weaning-induced liver involution a a a a a a a newly recognized postpartum biology is is is responsible for increasing the the risk of liver metastasis metastasis Understanding the the the unique metastasis-promoting environment in in in the the postpartum liver will help us develop
strategies to prevent and treat breast cancer liver metastases
As an ARCS Scholar
I have been able to meet intelligent caring women who are passionate about supporting young scientists This community along with the financial award have provided motivation to to keep me moving forward in in my doctoral work ”
Alexandra Quackenbush
Molecular and and Cellular Biosciences OHSU
ARCS Named Scholar
given by: Joan Foley & & Per Jarnberg and Jane & & Joe Gray