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                                Punctate nucleolar pattern








                                                                                      (AC-10)













































































            HEp-2 cells, in the metaphase, one to few little dots fluoresce



            within the condensed chromosome material. They correspond



            to the nucleolus organisator (NOR). The cytoplasm of mitotic




            cells may be weakly positive. Interphase cells show a granular



            fluorescence of the nuceloli.
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