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Homogenous nucleolar pattern
(AC-8)
HEp-2 cells, autoantibodies against PM-Scl exhibit
a homogeneous fluorescence of the nucleoli with
a simultaneous weaker, fine-speckled reaction of the
nucleoplasm. The condensed chromosomes of the mitotic
cells are unaffected; a fine, speckled fluorescence is shown
outside of the chromosomes.
A homogeneous fluorescence of the nucleoli also appears
on frozen sections of primate liver, as well as a very weak,
fine-speckled to reticular staining of the cell nucleus
