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Diagnostic Imaging   343


             administered intravenously and images made as soon as   the personnel even further (ALARA). Radiation safety
             radiopharmaceutical  equilibrium  in  the extracellular   rules may vary from state to state; therefore, the practi­
  VetBooks.ir  scanning agents is recommended.  99m Tc‐RBC is another   and comply with the specific state regulations.
                                                                 tioner should consult the local radiation safety officer
             space is achieved. A similar dose to that of the bone‐
             alternative for evaluating blood perfusion to soft tissues
             without the risk of bone uptake overlap. 83
               Phase 3, known as the delayed or bone phase, occurs   IMAGING EQUIPMENT
             several hours later when approximately 50% of the
             injected  radiotracer  has  attached  to  the  bone.  The   The gamma camera  contains a collimator  made of
             remainder of the tracer is excreted by the kidneys in the   small holes in a lead plate that allows only perpendicu­
             first 1 or 2 urine voids’ postinjection. The uptake pat­  lar γ‐rays through. This reduces scatter, thereby improving
             tern of normal bone is quite predictable and is described   image resolution. The γ‐rays interact with a fluorescent
             later in this chapter. The diaphysis of long bones has the   crystal (a thallium‐activated sodium iodide crystal is
             least uptake, and greatest uptake of the tracer occurs in   commonly used), changing the  γ‐energy to light pho­
             the juxtaphyseal and subchondral bone in normal sub­  tons. The light photons interact with a photocathode,
             jects. Increased radiotracer by or near the joints during   generating electrons that are amplified by an array of
             the delayed (bone) phase has been related to osteoarthri­  photomultiplier tubes. The x–y coordinates of the elec­
             tis (OA), various enthesopathies, periarticular bone scle­  trons are then recorded, and the image is reconstructed.
             rosis, septic arthritis, etc. These changes from the normal   The resultant image represents the geographic distribu­
             radiotracer pattern are discussed later in this chapter.  tion of the radiotracer in the horse. Images can be
                                                                 acquired in several matrices (64 × 64, 128 × 128 and
                                                                 256 × 256) (Figure 3.126). A 256 × 256 matrix to opti­
                                                                 mize image resolution.
             RADIATION SAFETY AND PROTECTION                       Various techniques have been devised to suspend the
               ALARA means that the radiation dose to which one is   gamma camera such as a stationary actuated lift or
                                                                                                               69
             exposed will be kept “As Low As Reasonably Achievable.”   track‐and‐column mounted detectors (Figure  3.127).
             These procedures and protocols are intended to protect   The tract system can moved around the horses, whereas
             the clinician, others, and the environment from unneces­  in the stationary system, the horse is moved around the
             sary risks due to radiation exposures.              camera.
               Film badges (personal dosimeters) should be worn to
             monitor the total cumulative radiation dose. Finger
             (ring) thermoluminescent dosimetry (TLD) film badges
             should be worn by personnel preparing and injecting the
             pharmaceutical.
               Eating, drinking, or smoking while handling a radio­
             active patient or radioactive materials is not permitted.
                                                            98
             Lead or tungsten syringe shields are designed to help
             reduce the radiation dose to the fingers.
               The nuclear medicine clinician should be conscious of
             two basic methods of exposure to ionizing radiation:        A               B
             internal contamination and external radiation. Care
             must be taken to avoid internal contamination through
             the accidental ingestion of the radionuclide. Latex gloves
             should always be worn when working with radiophar­
             maceuticals or radioactive patients.
               External radiation occurs when one is in the immedi­
             ate vicinity of the horse, for example, when scanning.
             The three basic rules of radiation safety are “time, dis­   C               D
             tance, and shielding.” Therefore, the time spent with the
             horse should be only that necessary for performing
             the study. Doubling the distance between the horse and the
             personnel reduces the radiation exposure by one fourth.
             Similarly, the exposure is quadrupled by halving the dis­
             tance from the horse. Standing 1 m away from the horse
             significantly reduces the radiation exposure to person­
             nel. For example, the exposure rate at the surface of a
             horse of 6.6 mrem/h decreases to 1.3 mrem/h at 1 m.         E               F
             Wearing a lead apron also reduces overall exposure
             while working with a radioactive  patient by filtering   Figure 3.126.  Image of right front foot acquired using several
             lower emitted energies.                             matrices. (A) 64 × 64. (B) 64 × 64 with statistical and heuristic image
               After the horse has been released, the stall is closed   noise extraction (SHINE) processing, a technique designed to
             off for an additional 24 hours before it is cleaned. This   reduce the Poisson noise contained within the image, preserving
             allows four more half‐lives of natural decay of the  99m Tc   resolution and contrast. (C) 128 × 128. (D) 128 × 128 (SHINE). (E)
             that was excreted via the urine, reducing the exposure to   256 × 256. (F) 256 × 256 (SHINE).
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