Page 535 - Adams and Stashak's Lameness in Horses, 7th Edition
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Lameness of the Distal Limb  501


               Due to the common inability to control digital pain   the digits in the ice slurry, most clinicians maintain
             with a safe dosing of NSAIDs, CRI of analgesic drugs     animals at risk of SRL in ice for 24–48 hours past the
  VetBooks.ir  ing the level of pain suffered by hospitalized laminitis
                                                                 abatement of clinical signs of sepsis.
             has been used to supplement NSAID therapy in decreas-
             patients. The use of “Pentafusion” (combination of keta-
             mine, morphine, lidocaine, detomidine, and aceproma-  Hoof Care in the Treatment of Acute and Early
                                                                 Chronic Laminitis
             zine;  Eric Abrahamsen,  BEVA  Proceedings, 2005)  has
             been described for use in severely painful cases of lami-  In the acute and early chronic laminitis case, it is
             nitis. The CRI is a valuable addition to laminitis therapy   likely that lamellar instability remains a prominent fac-
             because it takes some of the humane concerns away   tor. Ideally, in horses with severe acute and early chronic
             from the owner and veterinarian treating an animal in   laminitis, the force of the horse’s weight on the feet
             severe pain. Some of these drugs also affect GI motility;   should be reduced. To this end, slings have been used to
             therefore, the animals must be monitored closely for   enforce partial weight‐bearing, but availability and
             large intestinal motility/impaction. Additionally, the ani-  inadequate tolerance by the horse frequently result in
             mals may become unstable or overly sedate if the CRI   failure of this effort. Therefore, many treatment meas-
             rate is excessive. For a more focused approach, an epi-  ures are aimed directly at the foot. The two main objec-
             dural can be considered for analgesia in hindlimb   tives of hoof care are to redistribute the force of
             laminitis.                                          weight‐bearing away from the hoof wall and to decrease
                                                                 the extensor moment about the DIP joint.
                                                                   Several measures of varying efficacy attempt to redi-
             Therapy to Limit Structural Failure of the Lamellae
                                                                 rect weight‐bearing away from the wall by recruiting the
               The obvious overarching goal of therapies for the   frog, bars, and all or part of the sole to bear weight.
             horse at risk of or suffering from laminitis is limiting the   However, as discussed in Chapter 8, it must be remem-
             structural failure of the lamellae. The only therapy to   bered that the physiological role of the sole in weight‐
             consistently inhibit—or limit—lamellar structural fail-  bearing  is  not  fully  understood.  The  amount  of the
             ure in both the research and clinical setting is digital   ground surface that can be recruited to bear weight is
             hypothermia (also termed cryotherapy). 19,25,41  Although   highly variable between horses. In general, once the
             original work demonstrating efficacy of hypothermia     distal phalanx has displaced, pressure over the sole
             maintained the horses’ forelimbs in an ice/water slurry   under the displaced distal phalanx increases discomfort.
             to the level of the carpus,  more recent work has dem-  Thus, the clinician must weigh the benefits of possibly
                                   20
             onstrated that immersion of the foot up to the level of   decreasing  lamellar  stress  by  applying solar  support
             the pastern region is adequate to keep the hoof tempera-  with the risk of causing excessive solar pressure and
             ture less than 10 °C.  Although many clinicians use 5‐L   worsening the pain (and possibly the pathologic pro-
                              18
             intravenous fluid bags taped to the limbs to maintain   cess). Before considering other measures, the clinician
             the digits in the ice slurry, commercial alternatives exist   must decide whether  to leave shoes  on the feet  if the
             (e.g. Ice Spa Pro, Soft‐Ride, Inc.). Continuous hypother-  horse is shod. Shoes on firm surfaces concentrate stress
             mia in this manner has been demonstrated to protect the   around the perimeter of the foot (e.g. the hoof wall and
             lamellae from structural failure even when hypothermia   lamellae), and therefore removing them will likely be
             is not initiated until the onset of lameness.  Although   beneficial by removing this effect. Removing shoes also
                                                   25
             most experimental studies demonstrating efficacy of   makes other therapeutic measures more feasible, includ-
             digital hypothermia have been performed in models of   ing recruiting other parts of the ground surface of the
             SRL, the same protective effect was recently demon-  foot for weight‐bearing and modifying break‐over. The
             strated to occur when hypothermia was assessed in EHC   potential disadvantage of removing shoes in horses with
             model of endocrinopathic laminitis (Belknap and van   laminitis is that the removal process itself may cause
             Eps, unpublished data). In  the clinical setting,  digital   additional trauma to the lamellae.
             hypothermia is most commonly used as a prophylactic   The simplest way to recruit the sole, frog, and bars
             therapy in the septic equid at risk of laminitis. In a mul-  for weight‐bearing is to place the horse on bedding
             ticenter retrospective clinical study of the use of digital   material that readily conforms to the shape of the foot.
             hypothermia as a prophylactic therapy against laminitis   In this regard, sand is significantly better than shavings.
             in 130 equine enterocolitis cases, horses treated with   Peat has also been used. Deep deformable substrates
             digital hypothermia were ten times less likely to develop   also permit the horse to adjust the angle of its foot to
                                                         41
             laminitis than those not treated with hypothermia.  In   optimize comfort. However, the deep deformable sub-
             that study, there was a trend for a worse prognosis if   strates are not selective in how pressure is applied to the
             hypothermia were used intermittently than if not used at   ground surface of the foot. Various devices and materi-
             all (S. Holcombe, personal communication), indicating   als have been placed under the frog, sole, and bars to
             that it is very important that the digits need to be con-  recruit varying amounts of weight‐bearing.  These
             tinuously maintained in the hypothermic state. Although   include rolled gauze, Lilly pads, silicone putty, Styrofoam
             it varies between animals, ice usually needs to be replen-  insulation board (usually 2‐inch board), closed cell foam
                                                                                      3
             ished every 1–2 hours to maintain the hypothermic   (1.5 inches thick, 4  lbs/ft  density), and commercial pad
             state. Many practitioners only maintain the front digits   systems such as the Soft‐Ride boots (Soft‐Ride, Inc.,
             in ice due to the increased incidence of laminitis in the   Vermillion, OH). The closed cell foam has the advan-
             forelimbs; however, it is best to maintain all four limbs   tages of not crushing like Styrofoam does, and it can be
             in ice if possible. Although no studies have been per-  cut to bevel the ground surface to move the break‐over
             formed to ascertain the optimal time period to maintain   palmarad. The softer materials may offer the additional
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