Page 172 - BSAVA Guide to Pain Management in Small Animal Practice
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7   |  Cancer pain



        VetBooks.ir     CASE EXAMPLE 2 CONTINUED   ■   Analgesic ladder level   for management

                                                      at home  paracetamol codeine
              ANALGESIC PLAN                              mg kg Pardale V orally  8–1 h ;
                                                      tramadol  4 mg kg orally  1 h ;
              ■   Analgesic ladder level   initially    gabapentin  1 –1  mg kg orally  8h ;
                 methadone   .1– .  mg kg i.v.  4h ;   prednisolone  oral tapering dose .
                 radiotherapy     fractions of radiotherapy
                 to a total dose of     y ; prednisolone    Tips from the authors
                   .  mg kg orally  1 h ; gabapentin   In this case the invasive nature of the
                  1 –1  mg kg orally  8h ; fentanyl patch   sarcoma was associated with severe pain and
                 placement  changed every 7  hours ;   neurological dysfunction. Euthanasia was
                  oledronate  4 mg over 1  minutes with   o ered from the outset given the poor overall
                  .9  NaCl i.v. infusion .         prognosis.  owever, the owners wanted to
                                                   pursue treatment if her  oL could be
                                                   improved and maintained.





                  e ex  p e 3  Appendicular osteosarcoma


              HISTORY AND PRESENTATION             ANALGESIA PLAN
              A   year old male neutered Labrador   Analgesic ladder level    meloxicam   .1 mg
              Retriever was diagnosed with appendicular   kg orally   4h ; tramadol   –4 mg kg orally
              osteosarcoma.  here was local osteolytic    8–1 h ; gabapentin  1  mg kg orally  8h ;
              bone disease at the time of presentation with   verbal and physical comforting by the owner
              no nodal or distant metastases.  he right   following pain episodes.
              forelimb was amputated and a course of
              chemotherapy with carboplatin        Tips from the authors
              implemented.  hirty days after amputation,   Phantom limb pain is under reported in
              spontaneous pain episodes began and were   veterinary amputees but occurs in the
              subse uently documented in a pain diary   ma ority of human amputees. It is part of a
              kept by the owner.                   complex of symptoms that can also include
                                                   stump pain  neuroma formation at the
              TYPES OF PAIN                        surgical site  and phantom sensations. It is
                                                   chronic in nature, neuropathic in origin
              Severe, intense, short duration but multiple    although local neuroma formation may be
              episodes daily. Possible in ammatory   concurrent with local in ammation  and
              somatic pain at surgical site; clinical signs   appears to respond well, as in this case, to
              most compatible with neuropathic pain   gabapentin therapy. Chronic pain prior to
              including central sensiti ation  leading to   amputation may contribute to wind up and
              hyperalgesia .                       central sensiti ation.  ultimodal pre  and
                                                   perioperative analgesia appears to reduce
                                                   the incidence and severity of phantom pain in
                                                   human amputees.


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