Page 173 - BSAVA Guide to Pain Management in Small Animal Practice
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BSAVA Guide to Pain Management in Small Animal Practice



        VetBooks.ir     e ex  p e    Cutaneous epitheliotrophic


              lymphoma


             HISTORY AND PRESENTATION             ANALGESIC PLAN
             A 1  year old male neutered  ack Russell   Analgesic ladder level    methadone   .4
              errier was diagnosed with cutaneous   mg kg i.v.  4–8h  in hospital then speci c
             epitheliotrophic lymphoma; widespread local   anti neoplastic therapy including systemic
             ulcerative lesions generali ed to the skin and   glucocorticoids  dexamethasone  .  mg kg
             oral mucosa with nodal and hepatic   i.v.   4h  and   asparaginase  4   IU kg s.c.
             involvement   igure 7. 6 .           once . Reduced to level   for management at
                                                  home with oral glucocorticoids  prednisolone
                                                    mg kg orally   4h ; paracetamol and
                                                  codeine  paracetamol 1  mg kg orally  8h ;
                                                  gabapentin  1  mg kg orally  8h ; antibiotics
                                                   cephalexin 1  mg kg orally  1 h ;
                                                  antihistamines  chlorphenamine 4 mg orally
                                                   8h  and topical local anaesthetic ointment
                                                  on more painful skin lesions  E LA cream
                                                   lidocaine  .     prilocaine , topically  1 h,
                                                  avoiding ulcerated bleeding lesions and
                                                  covered with a patch to prevent oral
                                                  ingestion of cream .
                    Papular, pustular and nodular skin
                    lesions associated with epitheliotrophic
             lymphoma in a terrier dog.           Tips from the authors
                                                  Epitheliotrophic lymphoma is a slowly
             CLINICAL SIGNS                       progressive form of cutaneous neoplasia
             Severe pruritus, pain on touching the skin,   that in advanced cases can involve nodal
             hypersensitivity to stimuli including   and distant sites of visceral progression. It is
             subcutaneous in ections, anorexia due to   associated with signi cant chronic pain
             gingival pain on eating, facial oedema due to   associated with the skin and mucous
             lymphadenopathy, secondary pyoderma.  membranes. Advanced lesions are often
                                                  widespread and ulcerated.  his form of
                                                  lymphoma is poorly responsive to
             TYPES OF PAIN
                                                  chemotherapy and carries a very poor
             Severe and debilitating; in ammatory    long term prognosis. Palliation of pain
             somatic pain, visceral pain  organ distension    re uires consideration of the extent and
             lymph nodes, liver , chronic pain leading to   severity of the lesions and can be managed
             central sensiti ation and allodynia on the    with oral medications or in the most severe
             skin surface.                        cases, locali ed palliative radiotherapy.








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