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574   Laryngeal Paralysis


           Behavior/Exercise                   PROGNOSIS & OUTCOME               Technician Tips
           Limit exercise and discourage barking for 2-4   •  The prognosis is good for benign lesions if   When preparing for exams of animals with
  VetBooks.ir  helpful.                       •  Prognosis for malignant laryngeal tumors is   tongue depressor (to move the soft palate), an
                                                                                 laryngeal disease, have nearby a laryngoscope,
           weeks after surgery. Mild sedation may be
                                                complete resection is possible.
                                                                                 extra endotracheal tube (if the first becomes
           Possible Complications
                                                                                 biopsy  forceps, formalin,  22-  or 23-gauge
           •  Postoperative swelling            guarded:                         occluded with blood and mucus), long cup
                                                ○   Advanced disease is often detected at the
           •  Dysphagia and/or gagging            time of diagnosis.             needles of varying lengths (1-inch,   1 10 -inch,
           •  Pharyngeal dehiscence             ○   May not be surgically resectable  spinal needles), 6- or 12-mL syringes   a n d
           •  Laryngeal stenosis/webbing                                         microscope slides (for aspiration cytology), and
           •  Hypoparathyroidism/hypothyroidism   (if    PEARLS & CONSIDERATIONS  cotton-tip swabs (or gauze sponges and forceps
            removed during laryngectomy)                                         or suction) for clearing mucus or blood.
           •  Tumor recurrence or metastasis  Comments
           •  Obstruction, self-trauma of tracheostoma  •  Leaving the ventral part of the vocal cords   Client Education
           •  Subcutaneous  emphysema  secondary  to   intact may help prevent postoperative   Vocalization is lost after total laryngectomy.
            laryngeal/tracheal incision         laryngeal webbing.
                                              •  A CO 2  laser works well for surgical dissection   SUGGESTED READING
           Recommended Monitoring               and results in minimal inflammation and   Withrow SJ: Tumors of the respiratory system. In
           •  Monitor closely for upper airway obstruc-  hemorrhage.               Withrow SJ, editor: Small animal clinical oncology,
            tion secondary to postoperative pharyngeal   ○   When using a laser, ensure the endotracheal   ed 5, Philadelphia, 2013, Saunders, pp 432-462.
            swelling.                             tube is protected from the laser beam.
           •  Withhold water and food for at least 24-48   •  Some patients may benefit from a feeding   AUTHOR: Michael B. Mison, DVM, DACVS
                                                                                 EDITOR: Megan Grobman, DVM, MS, DACVIM
            hours in the postoperative period.  tube for postoperative nutritional support
           •  Routine  laryngoscopic  re-evaluation  is   (pp. 1106 and 1109).
            recommended to identify tumor recurrence   •  Rhabdomyoma, oncocytoma, and granular
            or laryngeal stenosis.              cell tumors share many cytologic and his-
           •  Periodic physical and radiographic evaluation   tologic features. These neoplasms should be
            is recommended to check for recurrence or   differentiated using histochemical staining
            metastasis.                         and immunohistochemical analysis.






            Laryngeal Paralysis                                                                    Client Education
                                                                                                         Sheet


            BASIC INFORMATION                 RISK FACTORS                       •  Dysphagia or megaesophagus is possible in
                                              •  Damage  to  the  recurrent  laryngeal  nerve   dogs with polymyopathy, polyneuropathy,
           Definition                           (blunt trauma, neoplasia, thoracic or cervical   or reflux/esophagitis.
           Lack of abduction of arytenoid cartilages and   surgery)              •  Aspiration  pneumonia/chronic  aspiration-
           vocal folds secondary to cricoarytenoideus   •  Any condition resulting in polyneuropathy   associated lung injury can develop secondary
           dorsalis muscle or recurrent laryngeal nerve   or polymyopathy          to dysphagia, EERD, esophageal or laryngeal
           dysfunction is common in old, large-breed dogs   ○   Myasthenia gravis  dysfunction.
           but rare in cats.                    ○   Immune-mediated disorder     •  Noncardiogenic  pulmonary  edema/
                                                ○   Diabetes mellitus              acute respiratory distress syndrome with
           Epidemiology                         ○   Hypothyroidism (cause/effect relationship   vigorous  inspiration  against  upper  airway
           SPECIES, AGE, SEX                      not established)                 obstruction
           •  Dogs: males more common; no sex predis-  ○   Toxins (lead, organophosphates)  Clinical Presentation
            position in cats                    ○   Progressive idiopathic polyneuropathy
           •  Congenital form: animals < 1 year old  •  Extraesophageal reflux disease (EERD)  DISEASE FORMS/SUBTYPES
           •  Acquired form: middle-aged/older dogs and   •  Cervical/intrathoracic masses  •  Unilateral: clinical signs mild or absent except
            cats (mean, 9-11 years of age)    •  In  cats,  associations  with  tick  paralysis,   in performance dogs or in cats
                                                idiopathic  polyneuropathy,  bronchogenic   •  Bilateral:  clinical  signs  apparent  in  most
           GENETICS, BREED PREDISPOSITION       carcinoma,  trauma,  and  brainstem  lesions   animals
           •  Acquired form commonly reported in Labra-  have been reported.
            dor retrievers, other large/giant breeds (Saint                      HISTORY, CHIEF COMPLAINT
            Bernards, Newfoundlands, Irish setters). No   GEOGRAPHY AND SEASONALITY  •  Varied progression over months to years
            breed predisposition in cats.     Hot weather/humidity and panting may   •  Signs  worsened  by  exercise  and  increased
           •  Congenital                      increase severity of clinical signs.  environmental temperature/humidity
            ○   Autosomal dominant: Bouviers des Flandres                        Early:
            ○   Associated with laryngeal paralysis poly-  ASSOCIATED DISORDERS  •  Inspiratory stridor; very common
              neuropathy  complex:  Leonberger  dogs,   •  Soft  palate  elongation  occurs  in  20%   •  Voice change (i.e., dysphonia)
              rottweilers, Pyrenean mountain dogs,   because of chronic increased inspiratory    •  Exercise  intolerance  with  associated  respi-
              Dalmatians, and black Russian terriers  effort.                      ratory  noise  and/or  breathlessness;  very
            ○   Other:  bull  terriers,  Siberian  Huskies,   •  Weakness and muscle wasting evident in up   common
              white-coated German shepherd dogs  to 50% of chronically affected dogs.  •  Coughing, gagging when eating

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