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Lameness   571


           •  Cytologic  evaluation  of  milk  reveals  cell   also be beneficial when there are puppies to   Prevention
             counts > 3000 cells/mcL with macrophages   nurse and lactation cannot be interrupted.  •  Provide  a  gradual  increase  of  food  intake
  VetBooks.ir  is present.                     Nutrition/Diet                       125%-150% maintenance requirements after   Diseases and   Disorders
             and neutrophils when inflammation (p. 618)
                                                                                    during the second half of pregnancy, and
                                               Diminishing food intake (one-half) and water
                                                                                    whelping.
                                                                                  •  Be sure mammary development is adequate
            TREATMENT
                                               for 2 or 3 days may help resolve galactostasis.
                                                                                    before cesarean section.
           Treatment Overview                  Behavior/Exercise                  •  Gradual weaning prevents galactostasis.
           Agalactia  treatment  mainly consists  of the   •  In hypogalactia or secondary agalactia, ensure   •  Considering the possible genetic component
           administration of galactagogues (prolactin   puppies suckle vigorously so that natural   of primary agalactia, breeding affected bitches
           increasing drugs). Treatment should be con-  stimulation of the glands occurs.  should be weighed against the potential of
           tinued for 3 days beyond when milk production   •  Galactostasis  may  benefit  from  wrapping   perpetuating the problem.
           appears. Failure of milk letdown requires   mammary area with an elastic bandage to
           treatment of primary cause (pp. 618 and 854).   protect from trauma. Any stimulation on the   Technician Tips
           Conversely, galactostasis could be treated with   mammary glands (e.g., padding, touching,   •  Slowly  and  calmly  introduce  puppies  to
           prolactin-decreasing drugs (dopamine agonists   or milking) should be avoided if lactation   dam after cesarean section. Anxious bitches
           or antiserotoninergics) if there are no puppies   is going to be terminated.  may benefit from mild tranquilization with
           to nurse.                                                                acepromazine. (See Video.)
                                               Drug Interactions                  •  Galactostasis  may  benefit  from  wrapping
           Acute General Treatment             High metoclopramide doses (5 mg/kg) for more   mammary area with an elastic bandage to
           •  Because  primary  agalactia  has  no  effec-  than 5 days usually cause behavioral side effects   protect from trauma. Any stimulation of the
             tive treatment, puppies should be hand     such as excitation and aggression. Domperidone   mammary glands (e.g., padding, touching,
             reared.                           provokes minimal (soft stools) or no side effects.  or milking) should be avoided if lactation
           •  Hypogalactia or secondary agalactia can be                            is going to be terminated.
             treated with                      Possible Complications
             ○   Metoclopramide 0.1-0.2 mg/kg SQ q 6-8h  When gross inflammatory changes of the   Client Education
             ○   Domperidone 2.2 mg/kg PO q 12h for   mammary glands accompany the accumulation   Teach clients to recognize lactation disorders
               4-6 days. Domperidone is a safer choice   of milk, mastitis may be present.  early so puppies can be saved.
               than metoclopramide because it does not
               cross the blood-brain barrier and therefore    PROGNOSIS & OUTCOME  SUGGESTED READING
               has no central side effects.                                       Romagnoli  S,  et  al:  Control  of  mammary  gland
           •  Failure of milk letdown can be treated with   Primary  agalactia  has  a  poor  prognosis  for   function in the bitch and queen: a review. Clin
             nasal oxytocin spray 10 minutes before lacta-  lactation, and neonates should be hand   Theriogenol 4:196-205, 2012.
             tion q 8h.                        reared. Failure in milk letdown and galacto-
           •  Anxious bitches may benefit from mild tran-  stasis typically respond to treatment or resolve   AUTHOR: Christina Gobello, MV, DVM, DECAR
                                                                                  EDITOR: Michelle A. Kutzler, DVM, PhD, DACT
             quilization with phenothiazine compounds   spontaneously.
             (e.g., acepromazine 0.1-0.25 mg/kg PO
             or 0.05-0.1 mg/kg IM or SQ), which also    PEARLS & CONSIDERATIONS
             increases prolactin release.
           •  In cases of galactostasis, reduction of milk   Comments
             production can be achieved by the admin-  Lactation disorders do not pose a risk for the
             istration of cabergoline 5 mcg/kg PO q 24h   female’s life, although they may cause consider-
             for 5-7 days. Diuretics and analgesics may   able neonatal losses.






            Lameness


            BASIC INFORMATION                  Clinical Presentation              PHYSICAL EXAM FINDINGS
                                                                                  •  Complete  general  physical  looking  for
           Definition                          HISTORY, CHIEF COMPLAINT             evidence of systemic abnormalities (e.g.,
           Alteration  of  gait  caused  by  structural  or   Thorough history is critical:  fever)
           functional abnormality in one or more limbs  •  Abnormal  gait  or  limping  observed  by     •  Complete orthopedic and neurologic exams
                                                owner                               (pp. 1143 and 1146). Orthopedic exam must
           Synonyms                            •  Determine which limb is affected.  include assessment of
           Favoring leg, limping               •  Difficulty rising                 ○   Abnormal posture
                                               •  Improves or worsens with exercise  ○   Joint effusion, warmth
           Epidemiology                        •  Holding limb up                   ○   Bone, joint, or muscle pain
           SPECIES, AGE, SEX                   •  Dragging limb or inappropriate placement   ○   Muscle atrophy
           Dog or cat, any age, either sex      (knuckling)                         ○   Thickening  or  bony  prominences  at  or
                                               •  Shifting limb lameness              near joints
           RISK FACTORS                        •  Acute or gradual onset            ○   Crepitus
           Trauma, genetics, obesity, overnutrition during   •  Progression over time  ○   Abnormal range of motion (ROM) in
           growth, tick bites, endocrinopathy                                         joints

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