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38    Aggression, Cat


           Differential Diagnosis             Acute General Treatment              to eliminate more common and likely dif-
           •  Depends   on   specific   cause   and   General supportive care      ferentials using the history and pathophysi-
  VetBooks.ir  Initial Database               Chronic Treatment                  •  Report  suspected  cases  of  food-borne
            pathophysiology
                                                                                   ologic results.
                                              Depends on initial outcome and residual
                                                                                   illness to the state’s FDA Consumer Com-
           •  Thorough,  complete  history,  including  all
                                                                                   Safety/ReportaProblem/ConsumerComplaint
            foods and products fed to the animal during   compromise to physiological functions  plaint  Coordinator  (http://www.fda.gov/
            the past 2-4 weeks; any husbandry conditions   Nutrition/Diet          Coordinators/default.htm)
            or activities allowing potential exposure to   If the patient’s normal diet is a suspected cause,
            other etiologic agents capable of producing   change the food. Select new diet based on status   Technician Tips
            similar clinical presentations    of major organ functions and on supportive   Ask about all foodstuffs, including treats or
           •  Minimum database: physical examination,   treatment goals.         table scraps.
            complete blood count, complete biochemical
            profile, urinalysis               Behavior/Exercise                  Client Education
                                              Prevent access to extraneous sources if cause is   •  Product  label  should  be  kept  as  long  as
           Advanced or Confirmatory Testing   determined to be from environmental exposure.  product from a package is being fed. Label
           Detection of suspected substance in food the                            contains key information (e.g., lot codes,
           animal was eating before illness. Detection   Possible Complications    best-by  dates,  manufacturing  location)  to
           assays should be validated for the substance in   Chronic deficits to major organ system function   allow follow-up sampling.
           food. Identical microbial pathogens should be   (e.g., renal, hepatic, endocrine) are possible.  •  Report a pet food product complaint elec-
           confirmed in food and biological samples from                           tronically through the Safety Reporting Portal
           the animal. Check with laboratory for specific    PROGNOSIS & OUTCOME   (https://www.safetyreporting.hhs.gov) or call
           tests and preferred sample preparation. If food                         your  state’s  FDA  Consumer  Complaint
           must be preserved before identifying appropriate   Grave prognosis for aflatoxicosis. Prognosis for   Coordinators (https://www.fda.gov/Safety/
           laboratories and tests, it is usually best to   other conditions varies by extent and duration   ReportaProblem/ConsumerComplaint
           double-bag in self-sealing plastic bags and freeze.   of exposure to etiologic agent, organ compro-  Coordinators/default.htm).
           Product label should also be saved.  mise, and treatment response.
                                                                                 SUGGESTED READING
            TREATMENT                          PEARLS & CONSIDERATIONS           National Research Council (NRC). 2005. Mineral
                                                                                   tolerance of animals revised, Washington, D.C.:
           Treatment Overview                 Comments                             National Academy Press.
           Change food to remove causative agent; stabilize   •  Food is generally easy to implicate, but rarely   AUTHOR: William J. Burkholder, DVM, PhD, DACVN
           critical physiologic functions; if definitive   confirmed as the cause when necessary   EDITOR: Jennifer A. Larsen, DVM, PhD, DACVN
           cause established, administer specific therapy   diagnostics are performed. Before investing
           as indicated.                        in testing food for adulterants, it is prudent







            Aggression, Cat                                                                        Client Education
                                                                                                         Sheet


            BASIC INFORMATION                   of feline development when cats learn about   extent to which seasonality affects aggression
                                                other species)                   in neutered cats is unknown.
           Definition                         •  In utero and perinatal malnutrition
           Feline aggression can be a threat, challenge,   •  Intracranial  disease  (e.g.,  toxoplasmosis,   Clinical Presentation
           or attack directed toward one or more   ischemic encephalopathy, intracranial neo-  DISEASE FORMS/SUBTYPES
           individuals and can be intraspecific (between   plasia, rabies), hepatic encephalopathy, lead   May be passive (covert) or active (overt) and
           cats) or interspecific (between different    poisoning, arthritis, sensory deficits, hyper-  involve a threat, challenge, or an actual attack
           species).                            thyroidism, epilepsy, feline lower urinary   •  Passive aggression may involve behaviors such
                                                tract disease, or any source of pain  as staring, sitting in doorways, or blocking
           Epidemiology                       •  Medications such ketamine and glucocorti-  access; owners may not recognize this as
           SPECIES, AGE, SEX                    coids have been implicated.        aggression.
           Onset commonly occurs at social maturity (2-4   •  Feline elimination disorders may be associ-  •  Active aggression is usually more obvious:
           years of age) but can be seen at any age. Aggres-  ated with unresolved intercat aggression   hissing, spitting, growling, actual fighting,
           sion is seldom recognized as a problem in kittens   between cats in the same household.  and biting.
           because they are assumed to be playing.
                                              CONTAGION AND ZOONOSIS             HISTORY, CHIEF COMPLAINT
           RISK FACTORS                       Bite or scratch wounds, pathogen transmission   •  Sudden onset of aggression between two or
           •  Underlying anxiety disorder     through bites or scratches (e.g., cat-scratch   more cats in a household or aggression to
           •  Hand rearing (failure to learn social rules   disease, retrovirus)   humans (owners or visitors). Aggression to
            from other cats)                                                       humans may be redirected aggression.
           •  Feral kittens                   GEOGRAPHY AND SEASONALITY          •  Cats may stalk and bite owners when they
           •  Lack of exposure to humans between 2-7   Aggression between intact cats may be more   move or attempt to approach/handle cat
            weeks of age (this is a critical sensitive period   apparent during the breeding season, but the   (overt aggression). A cat may also block access

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