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682   Nasopharyngeal Polyps


           Clinical Presentation              oral exam under anesthesia. Confirmation is
           DISEASE FORMS/SUBTYPES             based on histologic analysis.       TREATMENT
                                                                                 Treatment Overview
  VetBooks.ir  •  Ear (aural) polyp if mass grows into external   Differential Diagnosis  Nasopharyngeal polyp removal by gentle, steady
           •  Nasopharyngeal polyp
                                                                                 traction and avulsion can cure many cats.
            ear canal instead of nasopharynx
                                              •  Neoplasia (e.g., lymphoma, squamous cell
                                                carcinoma)
           HISTORY, CHIEF COMPLAINT           •  Infectious rhinitis             Recurrence rates are lower if combined with
                                                                                 oral prednisolone therapy or bulla osteotomy.
           •  Stertor                         •  Nasal/nasopharyngeal foreign body  Surgical removal may be required for aural
           •  Nasal discharge                 •  Nasopharyngeal stenosis         polyps in dogs.
           •  Sneezing                        •  Laryngeal paralysis
           •  Dyspnea                         •  Granuloma (cryptococcosis)      Acute General Treatment
           •  Dysphagia                       •  Hamartoma                       •  Oxygen  supplementation  (p.  1146)  if  in
           •  Gagging                                                              respiratory distress
           •  Voice change                    Initial Database                   •  General  anesthesia,  intubation,  and
           •  ± Head shaking or pawing at ears in cases   •  CBC, biochemistry panel, and urinalysis are   removal of the polyp: retract soft palate ros-
            of  concurrent  otitis  externa;  concurrent   usually normal.         trally (spay hook, stay sutures, or Babcock
            nasopharyngeal and aural polyps reported   •  Otoscopic exam (p. 1144):  forceps), and grasp the polyp gently at the
            in 18% of cats                      ○   Bulging of tympanic membrane from fluid   base with Allis tissue forceps. Apply slow,
           •  ± Vestibular signs or Horner’s syndrome if   or mass if otitis media present  steady traction to avulse stalk of polyp
            concurrent otitis externa progresses to otitis   ○   Aural polyp can extend through tympanic   from auditory tube/middle  ear. Minor to
            media/interna                         membrane into external ear canal.  moderate hemorrhage may occur, requiring
                                                ○   Otitis externa if tympanic membrane   a short period of digital pressure or local
           PHYSICAL EXAM FINDINGS                 ruptured                         packing.
           •  Increased inspiratory noise (often stertor)                        •  To  reduce  recurrence  rate,  oral  pred-
           •  Mucoid  to  mucopurulent  nasal  discharge   Advanced or Confirmatory Testing  nisolone 1-2 mg/kg PO q 24h for 2 weeks,
            (unilateral or bilateral)         •  Oral exam under anesthesia (p. 1125):  then  0.5-1 mg/kg  PO  q  24h  for  1  week,
           •  Gagging                           ○   Palpable mass dorsal to soft palate or mass   then 0.5-1 mg/kg PO q 48h for 7-10 days
           •  Unilateral deafness in 35% of cats because   protruding into oropharynx  or ventral bulla osteotomy with removal
            of concurrent middle ear disease (hard to   ○   Retraction of the soft palate may increase   of the epithelial lining; culture from
            recognize)                            visualization                    the bulla is also indicated at the time of
           •  Uncommon  signs  include  otitis  externa,   ○   Often, this is the only confirmatory test   surgery.
            submandibular swelling, regurgitation,   required.                   •  Perendoscopic transtympanic traction (PTT)
            head tilt, ataxia, nystagmus, or facial nerve    ○   Removal may be performed immediately   and laser ablation have been described for
            palsy.                                (see Acute Treatment).           aural poly removal and may be associated
           •  ± Horner’s syndrome: miosis, ptosis, enoph-  •  Skull radiographs (seldom necessary)  with lower recurrence rates.
            thalmos, and third eyelid prolapse on affected   ○   Increased soft-tissue density in pharynx
            side                                  (lateral or oblique lateral view)  Chronic Treatment
           •  ± Rarely, severe inspiratory dyspnea  ○   Evidence of otitis media: enlarged or   Antibiotics if bacterial otitis media is suspected
                                                  thickened bulla containing  increased   (e.g., amoxicillin-clavulanate 62.5 mg/CAT PO
           Etiology and Pathophysiology           soft-tissue density (rostrocaudal view)  q 12h until culture results return)
           •  Exact  cause  is  unknown,  but  proposed   ○   May be normal
            causes include inflammatory conditions and   •  CT                   Possible Complications
            congenital persistence of branchial arches.  ○   Focal,  contrast-enhancing,  soft-tissue   •  Horner’s  syndrome:  ≈80%  of  cases  after
            ○   The significance of herpesvirus, calicivirus,   nasopharyngeal mass with stalk  bulla osteotomy; can also occur with polyp
              bacteria, or fungi recovered from polyps   ○   Rim enhancement on CT differentiates   traction  avulsion  alone.  Usually  resolves
              is questionable.                    from fluid and other neoplasia   within 1 month
           •  Proliferation  of  the  auditory  (eustachian)   ○   Increased fluid and soft-tissue density   •  Otitis interna: ≈40% of cases after ventral
            tube or tympanic bulla mucosal epithelium   in bulla. Bulla wall is thickened and   bulla osteotomy; ataxia and head tilt can
            likely obstructs drainage from the middle   pathologically expanded. Bilateral bulla   affect quality of life.
            ear. The resulting fluid accumulation and   disease in 31%
            inflammation  (otitis  media)  can  extend   ○   Enlarged ipsilateral medial retropharyngeal   Recommended Monitoring
            into the inner ear (otitis interna) or drain   lymph node in 62%     •  Re-evaluate nasopharynx, bulla, and external
            through the tympanic membrane (otitis   •  Endoscopy: both ear canals and nasopharynx  ear canal if clinical signs recur.
            externa) and provokes formation of a fibrous     ○   Aural polyps: pink-red, multilobulated   •  Repeat  otoscopic  exam and  otic  cytologic
            polyp.                                masses in the ear canal/tympanic cavity.   exam if otitis externa is present.
           •  Enlarged mass fills the nasopharyngeal region,   Waxy  cerumen  is  common,  If  intact,
            obstructing caudal nasal drainage and airflow,   thickening/bulging of the tympanum due    PROGNOSIS & OUTCOME
            and  eventually  impedes  inspiration  and   to impaired auditory tube drainage is often
            swallowing causing nasal discharge.   seen. Myringotomy may be performed   •  Polyp  regrowth  occurs  in  11%-50%  of
           •  Alternatively,  the  tympanic  membrane   after exam.                cats treated with traction avulsion without
            ruptures, and the mass extends into the   ○   Nasopharyngeal polyps: direct visualization   concurrent ventral bulla osteotomy.
            horizontal ear canal.                 of mass in the nasopharynx       ○   Recurrence uncommon with traction
                                              •  Histologic exam                     removal followed by postoperative
            DIAGNOSIS                           ○   Well-vascularized fibrous tissue covered by   prednisolone
                                                  stratified squamous or columnar epithelium  ○   Ventral bulla osteotomy prevents recur-
           Diagnostic Overview                  ○   Inflammatory cells, primarily lymphocytes,   rence in most cats after traction removal.
           The primary method of diagnosis is visualizing   plasma cells, and macrophages, present in   •  Deafness in affected ear often persists after
           a firm, pink mass dorsal to the soft palate on   the stroma             polyp removal.

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