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684   Necrotizing Fasciitis


           •  Foreign body/abscess              out infectious causes can exacerbate infectious   brace so it fits properly, and the owner and
                                                                                   clinician should monitor the animal.
                                                diseases.
           •  Trauma/fracture                 •  If spinal instability is suspected, a neck brace   •  Paralysis or death is possible with acute spinal
  VetBooks.ir  Initial Database                 for immobilizing the neck can provide pain   Recommended Monitoring
           •  Neoplasia
                                                                                   injury.
                                                relief and prevent further tissue damage. Cage
           •  Neurologic and orthopedic exams (p. 1136
                                                the same purpose.
            and 1143)                           rest and exercise restriction are important for   Any dog with signs of neck pain should be
           •  CBC, serum biochemistry panel, urinalysis                          closely monitored for the development of
           •  Neck radiographs                Chronic Treatment                  neurologic conditions such as ataxia, paresis,
                                              Specific treatment of the underlying cause is   paralysis, and respiratory impairment. These
           Advanced or Confirmatory Testing   paramount. Nonspecific treatment should not   conditions often warrant further intervention
           •  Myelography, CT, or MRI (p. 1132): very   interfere with diagnosis or treatment of the   and intensive care.
            useful for spinal imaging         underlying cause:
            ○   Myelograms with dynamic views (under   •  Nonsteroidal   antiinflammatory   drugs    PROGNOSIS & OUTCOME
              careful  patient  manipulation)  may  be   (NSAIDs (e.g., carprofen 2 mg/kg PO q 12h,
              useful for diagnosis of CSM and for IVDD   etodolac 10-15 mg/kg PO q 24h, deracoxib   Varies, depending on underlying disease process
              and some spinal tumors.           1-2 mg/kg PO q 24h, firocoxib 4-5 mg/kg
            ○   MRI is best for spinal cord and nerve   PO q 24h, grapiprant 2 mg/kg PO q 24h,    PEARLS & CONSIDERATIONS
              lesions and increasingly used for IVDD.  or meloxicam 0.1 mg/kg PO q 24h)
            ○   CT  is  best  for  evaluating  bony  lesions   •  Low-dose  glucocorticoids:  never  combine   Comments
              (spinal tumors or fractures) and can be   with NSAIDs. Glucocorticoids should be   •  Neck pain in certain dog breeds is a common
              used as an adjunct to myelography.  tapered after improvement. Typical recom-  problem in clinical practice.
           •  Cerebrospinal fluid (CSF) tap if meningitis or   mended course: prednisone 0.25-0.5 mg/kg   •  All  dogs  being  considered  for  nonspecific
            neoplasia is suspected (pp. 1080 and 1323)  PO q 12h × 4-5 days, then q 24h for 4-5   supportive treatment should first have cervi-
           •  Serologic titers or polymerase chain reaction   days, then q 48h for 4-5 doses  cal spinal radiographs.
            (PCR) testing of blood or CSF as appropriate   •  Amantidine 3-5 mg/kg PO q 24h, tramadol   •  Cage rest, typically for at least 4 weeks, is a
            (e.g., CDV, Brucella card test)     1-4 mg/kg  PO  q  8-12h,  or  gabapentin   critical component of conservative treatment
           •  Aspiration or biopsy of abnormal tissues  10 mg/kg  PO  q  8h  for  adjunctive  pain   for dogs with IVDD.
           •  Ultrasound  of  soft  tissues  to  locate  an   control            •  If  a  dog  does  not  respond  appropriately
            abscess, foreign body, neoplasm, or other   •  Acupuncture (p. 1056)   to  nonspecific  supportive  therapy,  the
            such abnormalities                •  Surgery if indicated by imaging, emergent   clinician should perform further diagnostic
           •  Surgical exploration: histopathologic evalu-  disorder, and/or lack of response to conserva-  testing.
            ation of tissue samples, bacterial culture and   tive therapy
            susceptibility (C&S)              •  Treatment  of  specific  infectious  disease  if   Technician Tips
           •  Urine culture ± blood culture (p. 1333) if   identified            •  Observe for any signs of developing weakness
            there is a concern about discospondylitis                              or neurologic deficits.
                                              Behavior/Exercise                  •  Progressive  swelling/pain  and  heat  may
            TREATMENT                         •  Exercise restriction              alert to need for additional diagnostics and
                                              •  Use of a harness instead of a collar for walks  treatment.
           Treatment Overview                 •  Elevation of food and water bowls
           In most cases, therapeutic tenets are relief of                       Client Education
           pain, immobilization if movement is detrimental   Drug Interactions   •  Owners should be informed to use a harness
           or painful, and treatment of underlying disease   Do not coadminister NSAIDs with glucocorti-  for walks.
           process.                           coids due to risk of serious or life-threatening   •  Cage rest is critical in conservative manage-
                                              gastroenteritis  and gastrointestinal (GI)   ment of IVDD.
           Acute General Treatment            ulceration.                        •  The clinician should inform the owner about
           •  Animals  with  acute  severe  neck  pain  are                        exercise restrictions.
            often initially treated with cage rest and   Possible Complications
            medications such as analgesics (hydromor-  •  Adverse  reactions  to  the  medication,   SUGGESTED READING
            phone  0.1-0.2 mg/kg  SQ,  IM,  or  IV  q   especially GI ulceration caused by taking   Platt SR, et al: Cervical spine. In Tobias KM, et al,
            4-6h,  buprenorphine  10-30 mcg/kg  IV  q   glucocorticoids and NSAIDs simultaneously  editors: Veterinary surgery: small animal, St. Louis,
            6-8h, or butorphanol 0.1-0.2 mg/kg IV as   •  Pneumonia is a common complication in   2012, Saunders, pp 410-448.
            needed up to q 4h) and/or muscle relaxants   dogs that have tetraparesis and are recumbent.  AUTHOR: David A. Puerto, DVM, DACVS
            (methocarbamol  20-50 mg/kg  PO  q  8h).   •  Respiratory  obstruction  is  possible  with  a   EDITOR: Leah A. Cohn, DVM, PhD, DACVIM
            Empirical glucocorticoids given before ruling   neck brace; it is important to adjust the




            Necrotizing Fasciitis                                                                  Client Education
                                                                                                         Sheet


                                                                                 Epidemiology
            BASIC INFORMATION                 to tissue necrosis, severe pain, and septic
                                              shock                              SPECIES, AGE, SEX
           Definition                                                            Dogs and cats of any age or sex
           Fulminant,  rapidly  progressing  infection  of   Synonyms
           the  skin, subcutis,  and  fascia that  can lead   Flesh-eating disease, flesh-eating bacteria

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