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700   Obesity


            TREATMENT                           ○   Metronidazole toxicosis: typically good   Technician Tips
                                                  prognosis with discontinuation of met-  •  Use  caution  when  cleaning  external  ear
           Treatment Overview
  VetBooks.ir  •  Supportive care                 therapy may speed improvement.  •  Patients often do better with self-induced
                                                  ronidazole and supportive care. Diazepam
                                                                                   canals.
                                                                                   movement. Quick movements can exacerbate
           •  Alleviate nausea if present.
                                                                                   vestibular disease.
           •  Treat underlying cause.
           Acute and Chronic Treatment         PEARLS & CONSIDERATIONS           Client Education
                                              Comments
           •  Vestibular:  supportive  care  (pp.  403  and   •  Nystagmus is usually absent with bilateral   •  Signs often improve within several days.
            1037) and treatment of the inciting disorder  vestibular disease.    •  Diagnostics  evaluate  possible  causes,  need
            ○   Prolonged use of antinausea drugs can   •  Physiologic nystagmus can persist for a few   for specific treatment, and help determine
              delay vestibular compensation/recovery.  seconds after head rotation has stopped.  prognosis.
            ○   Discontinue metronidazole.    •  Idiopathic  peripheral  vestibular  disease   •  Harness and sling helps patient handling.
                                                usually causes nystagmus; nystagmus should   •  Nightlights can help. Loss of balance (ves-
           Possible Complications               resolve spontaneously in 1-2 weeks.  tibular disease) together with low visibility
           Use caution when cleaning external ear canals.   ○   Compensation can also occur initially with   can make it difficult for animals to stay
           If tympanic membrane is ruptured, most   other disease processes.       oriented and upright.
           cleaning solutions and antibiotics can cause    ○   When compensation occurs with causes
           damage.                                other than idiopathic vestibular disease   SUGGESTED READING
                                                  or vascular causes, then decompensation/  Rossmeisl JH: Vestibular disease in dogs and cats. Vet
            PROGNOSIS & OUTCOME                   relapse typically occurs.        Clin North Am Small Anim Pract 40:81-100, 2010.
                                              •  Many (but not all) patients with nystagmus
           •  Spontaneous nystagmus often resolves within   caused by central vestibular disease have other   AUTHOR: James Lavely, DVM, DACVIM
                                                                                 EDITOR: Leah A. Cohn, DVM, PhD, DACVIM
            the first several days of a vestibular event.  CNS signs (mentation changes, cranial nerve
           •  Vestibular: varies, based on underlying cause  deficits, proprioceptive deficits).
















            Obesity                                                                  Bonus Material   Client Education
                                                                                          Online
                                                                                                         Sheet

            BASIC INFORMATION                 •  Crossbreed, mixed-breed, and Manx cats are   •  Hypertension (dogs)
                                                at higher risk for obesity.      •  Pancreatitis (dogs)
           Definition                                                            •  Feline lower urinary tract disease (cats)
           In companion animals, obesity is defined as   RISK FACTORS            •  Urolithiasis (cats and possibly dogs)
           25%  above  ideal  body  weight,  which  cor-  •  Neutering (dogs and cats)  •  Respiratory compromise (dogs and cats)
           responds to a body condition score (BCS) of   •  Age (dogs and cats)  •  Dystocia (dogs and cats)
           7 on a 9-point scale.              •  Female sex (dogs)               •  Exercise intolerance (dogs and cats)
                                              •  Male sex (cats)                 •  Heat intolerance (dogs and cats)
           Epidemiology                       •  Strict indoor housing (cats)    •  Decreased  immune  function  (dogs  and
           SPECIES, AGE, SEX                  •  Apartment living (dogs and cats)  cats)
           Prevalence ranges up to 63% in some   •  Orthopedic or neuromuscular disease imped-  •  Increased anesthetic risk (dogs and cats)
           canine populations and 59% among cats.   ing mobility                 •  Decreased life span (dogs and cats)
           Incidence increases with age in both species.   •  Medications  such  as  phenobarbital  and
           Female dogs and male cats appear to be    glucocorticoids (dogs > cats)  Clinical Presentation
           predisposed.                       •  Endocrine  disease  (e.g.,  hypothyroidism,   Noted on routine wellness consultation or with
                                                hyperadrenocorticism, acromegaly)  associated concurrent disease
           GENETICS, BREED PREDISPOSITION
           •  Predisposed dog breeds include Labrador and   ASSOCIATED DISORDERS  HISTORY, CHIEF COMPLAINT
            golden retrievers, Cairn and Scottish terriers,   •  Hyperlipidemia/dyslipidemia (dogs and cats)  Associated concurrent issue, such as exercise
            collies, basset hounds, Cavalier King Charles   •  Insulin  resistance  and  glucose  intolerance   intolerance or impaired mobility. Many owners
            and cocker spaniels, dachshunds, rottweilers,   (pre-diabetes; dogs and cats)  do not recognize or acknowledge that their
            Saint Bernards, and Newfoundlands. A   •  Diabetes mellitus (dogs and cats)  pet is obese.
            mutation in the proopiomelanocortin gene   •  Hepatic lipidosis (cats)
            (POMC) is associated with body weight,   •  Orthopedic disease (dogs and cats)  PHYSICAL EXAM FINDINGS
            adiposity, and greater  food motivation in   •  Dermatological disease (dogs and cats)  Excessive  adipose  tissue  is  generally  readily
            Labrador retrievers.              •  Oral cavity disease (cats)      recognized, but ascites or organomegaly may
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