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Peritonitis, Septic   779


                                                                                   PROGNOSIS & OUTCOME

  VetBooks.ir                                                                     •  Excellent  prognosis  with  effective  surgical   Diseases and   Disorders
                                                                                    correction; resolution of clinical signs in 85%
                                                                                    of cases
                                                                                  •  Postoperative mortality rates of 5%-14%
                                                                                  •  Left uncorrected, the patient may remain free
                                                                                    of clinical signs, but the risk of complications
                                                                                    persists.

                                                                                   PEARLS & CONSIDERATIONS
                                                                                  Comments
                                                                                  •  PPDH  is  the  most  common  congenital
            A                                              B                        pericardial disorder in dogs and cats.
                                                                                  •  PPDH is a congenital defect, in contrast to a
           PERITONEOPERICARDIAL DIAPHRAGMATIC HERNIA  Lateral  (A) and dorsoventral (B) thoracic
           radiographs of a 1-year-old cat with PPDH. Note cardiomegaly, irregular soft tissue, fat, and gas opacities over   pleuroperitoneal diaphragmatic hernia, which
           the heart, indistinct diaphragm, and dorsal mesothelial remnant (arrows). (Courtesy Dr. Stephanie Nykamp.)  may be congenital or the result of trauma.
                                                                                  •  PPDH is important to rule out for cardio-
                                                                                    megaly, particularly in young animals with
                                                                                    cranial abdominal or sternal defects.
           •  Additional testing is rarely needed. Upper   Acute General Treatment
             GI barium series or contrast peritoneography   •  Oxygen supplementation  Technician Tips
             (1-2 mL/kg of water-soluble, nonionic,   •  Surgical  correction  by  laparotomy:  return   •  Ventilation  techniques  allowing  slow
             iodinated radiopaque contrast agent injected   of all abdominal organs to correct locations   and controlled re-expansion of the lungs
             aseptically into peritoneal cavity, followed   and closure of diaphragmatic defect. Caudal   postoperatively may diminish the risk of
             by elevation of the caudal end and thoracic   sternotomy may be required for adhesions   re-expansion pulmonary edema.
             radiography) may confirm PPDH if other   or reconstruction of a large defect.  •  For  the  uncorrected  PPDH  patient,  it  is
             tests are inconclusive, but false-negatives are   •  Assessment of liver function before general   critical to educate clients about monitoring
             common.                            anesthesia                          for signs of respiratory, GI, or circulatory
                                                                                    compromise as listed above.
            TREATMENT                          Possible Complications
                                               •  Left uncorrected, the risk of hepatic or splenic   SUGGESTED READING
           Treatment Overview                   incarceration, bowel obstruction, or cardiac   Burns CG, et al: Surgical and non-surgical treatment
           Surgical correction is indicated to eliminate   tamponade and right-heart failure persists.  of peritoneopericardial diaphragmatic hernia in dogs
           clinical signs and prevent vascular com-  •  Surgical complication rate is low but may   and cats: 58 cases (1999-2008). J Am Vet Med
           promise or obstruction of organs. It may   include difficulty ventilating, hypotension,   Assoc 242:643-650, 2013.
           be  appropriate  not  to  pursue  surgical   re-expansion pulmonary edema, and pleural   AUTHOR: M. Lynne O’Sullivan, DVM, DVSc, DACVIM
           repair in some cases (e.g., animal without   effusion. Postoperative pericardial cyst and   EDITOR: Meg M. Sleeper, VMD, DACVIM
           clinical signs, small incidentally discovered    constrictive pericarditis have each been
           PPDH).                               reported in one cat.





            Peritonitis, Septic                                                                    Client Education
                                                                                                          Sheet


            BASIC INFORMATION                  urinary tract obstruction with urinary tract infec-  •  Lethargy, anorexia, collapse
                                               tion, severe colitis, trauma (blunt or penetrating)  •  Vomiting, regurgitation
           Definition                                                             •  Owners  may  notice  abdominal  distention
           Peritonitis is local or generalized inflammation   Clinical Presentation  or pain.
           of the peritoneum. A diagnosis of bacterial   DISEASE FORMS/SUBTYPES
           septic peritonitis is based on identification of   •  GI tract perforation or dehiscence  PHYSICAL EXAM FINDINGS
           intracellular bacteria or other infectious agents   •  Leakage  or  translocation  of  bacteria  from   •  Tachycardia  (bradycardia  possible  in  cats)
           (e.g., Candida) in abdominal effusion.  other  abdominal  organ  (e.g.,  pyometra,   and signs of hypovolemic or septic shock
                                                prostatic or hepatic abscesses, cholecystitis,   (p. 907)
           Epidemiology                         urinary tract)                    •  Abdominal  pain  indicated  by  tension,
           SPECIES, AGE, SEX                   •  Penetrating abdominal trauma      guarding, or prayer position (may be
           Younger  animals  prone  to  ingesting  foreign                          disproportionately subtle for the degree of
           material, older animals with gastrointestinal   HISTORY, CHIEF COMPLAINT  inflammation or be mimicked by apprehen-
           (GI) neoplasia or biliary disease, and intact   •  History suggestive of precipitating cause:  sion or back pain)
           animals are predisposed.             ○   Medications predisposing to GI ulceration   •  Abdominal effusion
                                                  (e.g., nonsteroidal antiinflammatory drugs,   •  Fever or hypothermia
           RISK FACTORS                           glucocorticoids)                •  Altered mentation
           GI surgery, GI ulcer/necrosis, liver lobe torsion   ○   Penetrating wounds, foreign object inges-  •  Other  findings  related  to  cause  (e.g.,  dis-
           or neoplasia, closed pyometra, septic prostatitis,   tion, or prior GI surgery  tended uterus ± purulent vaginal discharge if

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