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779.e2  Peritonitis




            Peritonitis                                                                            Client Education
                                                                                                         Sheet
  VetBooks.ir

            BASIC INFORMATION
                                                ○   Organ inflammation/ischemia
                                                                                 •  Icterus
                                                ○   Iatrogenic                   •  Previous abdominal incision
           Definition                         Nonseptic versus septic:           •  Hematuria, pyuria
           Inflammation of the peritoneum     •  Nonseptic                       •  Purulent or hemorrhagic vaginal discharge
                                                ○   Peritoneal inflammation: mechanical   Findings related to sepsis/septic shock:
           Epidemiology                           trauma (e.g., intraabdominal surgery),   •  Hyperemia, brick-red mucous membranes,
           SPECIES, AGE, SEX                      pancreatitis                     increased or decreased capillary refill time,
           •  Any species, breed, age, or sex   ○   Sterile foreign material: urine, bile,   tachycardia, tachypnea, hyperdynamic or
           •  Cat: feline infectious peritonitis (FIP [p. 327])  iatrogenic (e.g., surgical sponge)  hypodynamic pulse, fever or hypothermia
                                              •  Septic                            (cats)
           RISK FACTORS                         ○   Contamination and subsequent infection
           •  Abdominal trauma                    of the peritoneal cavity by an infectious   Etiology and Pathophysiology
            ○   Blunt                             agent (bacteria most commonly, viruses,   •  Peritoneal inflammation causes vasculitis and
            ○   Penetrating                       protozoa, yeast)                 increased capillary permeability.
           •  Intraabdominal surgery                                             •  Movement  of  large  volumes  of  fluid  into
            ○   Gastrointestinal (GI) procedures  HISTORY, CHIEF COMPLAINT         peritoneal cavity
           •  Inflammatory/infectious disease of abdominal   History varies, depending on underlying cause:  ○   Severe hypovolemia or hypovolemic
            organ(s)                          •  Known trauma                        shock
            ○   Cholecystitis/cholangiohepatitis  •  Ingestion of foreign material  ○   Accompanying loss of protein and
            ○   Prostatitis/prostatic abscess  •  Previous abdominal surgery         electrolytes
            ○   Pancreatitis                  •  Ongoing  or  recent  treatment  for  intra-  •  Development of coagulation abnormalities
            ○   Pyometra                        abdominal organ disease            due to release of inflammatory mediators
            ○   Pyelonephritis                •  Urinary tract obstruction         and cytokines
            ○   Cystitis                      •  Heat cycle in previous month      ○   Hypercoagulable or hypocoagulable state
           •  GI ulceration                   •  NSAID and/or glucocorticoid use   ○   DIC
            ○   Nonsteroidal antiinflammatory drugs   Chief complaint varies, depending on underly-  •  If  septic,  bacterial  translocation  into  the
              (NSAIDs)                        ing cause of peritonitis:            bloodstream
            ○   Glucocorticosteroids          •  Nonspecific complaints            ○   Bacteremia
            ○   GI neoplasia                    ○   Lethargy, fever, anorexia, vomiting,   ○   Sepsis or septic shock
            ○   Foreign body ingestion            decreased/no fecal production, diarrhea
           •  Cat: environment conducive to transmission   •  Complaints related to cause of peritonitis   DIAGNOSIS
            of FIP                              ○   Wound(s) in abdominal area
                                                ○   Jaundice                     Diagnostic Overview
           CONTAGION AND ZOONOSIS               ○   Vulvar discharge             Diagnosis  is suspected  based on  presenting
           Cat: transmission of coronavirus FIP is mainly   •  Urination         history and physical exam findings. Confirma-
           by the fecal-oral route; mutation of coronavirus   ○   Stranguria     tion requires demonstration of inflammation
           from less pathogenic form to FIP variant is   ○   Oliguria/anuria     in intraabdominal fluid and evaluation
           necessary to cause clinical FIP.     ○   Hematuria                    of the fluid to determine the cause of the
                                              •  Complaints related to developing peritonitis  peritonitis.
           ASSOCIATED DISORDERS                 ○   Signs of abdominal discomfort: reluctance
           •  Sepsis/septic shock                 to lie down or discomfort when lying   Differential Diagnosis
           •  Coagulopathy/disseminated  intravascular   down, praying posture, pain on handling/  •  Abdominal pain: rule out other causes (organ
            coagulation (DIC)                     touching abdomen (often subtle)  enlargement, organ inflammation).
           •  Systemic inflammatory response syndrome   ○   Abdominal distention  •  Nonabdominal pain: rule out
            (SIRS)                                                                 ○   Spinal (e.g., intervertebral disc disease,
           •  Acute respiratory distress syndrome (ARDS)  PHYSICAL EXAM FINDINGS     trauma)
           •  Multiple  organ  dysfunction  syndrome   Findings related to peritoneal inflammation:  ○   Pelvic fracture/dislocation
            (MODS)                            •  Nonspecific: lethargy, fever, dehydration  ○   Thoracic (e.g., trauma-related rib fractures,
                                              •  Specific                            diaphragmatic hernia, other intrathoracic
           Clinical Presentation                ○   Signs of acute abdomen           disease [e.g., pleural pain])
           DISEASE FORMS/SUBTYPES               ○   Pain on abdominal palpation: localize to   ○   Limbs: joint pain/polyarthritis
           Primary versus secondary:              specific region of abdomen if possible;   •  Abdominal distention, fluid (abdominocen-
           •  Primary: peritoneal inflammation or infec-  may be absent or subtle (especially in cats)  tesis [p. 1056] for confirmation)
            tion without pre-existing intraabdominal   ○   Abdominal distention (fluid and/or mass)  ○   Associated  with  peritonitis  (septic  or
            condition                         Findings related to underlying cause of   nonseptic exudate)
            ○   FIP                           peritonitis:                         ○   Not associated with peritonitis (transudate,
            ○   Rare occurrence of bacterial (mycobacteria)   •  Abdominal trauma (e.g., wounds, contusions,   modified transudate, hemorrhage, ascites,
              and protozoal primary infections  disruption of the abdominal wall)    neoplastic effusion) (p. 79)
           •  Secondary: peritoneal inflammation or infec-  •  Linear foreign body (p. 353) caught around   •  Abdominal distention, mass
            tion caused by intraabdominal pathologic   tongue base. The clinician should apply   ○   Not associated with peritonitis: organ
            condition                           dorsal pressure with thumb externally   enlargement (e.g., hepatomegaly, spleno-
            ○   Disruption of GI or urogenital tracts  between mandibles to raise tongue for a   megaly), cyst formation (e.g., paraprostatic
            ○   Penetrating trauma              proper sublingual exam.              cyst)

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