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820   Preputial Discharge


            quickly  and  with  fewer  side  effects  than   •  Ovariectomy  or  ovariohysterectomy  pre-  should be performed as early in gestation
            using either individually.          vents the problem of unwanted pregnancy   •  Shortening  the  luteal  phase  shortens  the
                                                                                   as possible.
  VetBooks.ir  initiated after 50 days’ gestation, birth of   Technician Tips      interestrous  interval.  Clients  should  be
           •  If  pregnancy  termination  protocols  are
                                                permanently.
                                                                                   advised to expect the next cycle to occur
            viable puppies or kittens may occur and is
            not recommended.
                                                anorexia, vaginal discharge, discomfort,
           •  Gonadotropin-releasing hormone (GnRH)   •  Side effects of pregnancy termination include   sooner than normally expected.
            agonists, GnRH antagonists, GnRH vac-  depression, and lactation.    SUGGESTED READING
            cines, as well as progesterone antagonists are   •  Side effects of PGF 2a  (occur 30-40 minutes   Eilts BE: Pregnancy termination in the bitch and
            effective treatments for misalliance in dogs.   after  injection;  decrease  with  subsequent   queen. Clin Tech Small Anim Pract 17:116-123,
            Currently these products are not available   injections) include salivation, panting, vomit-  2002.
            in the United States.               ing, defecation/diarrhea, and vocalization in   AUTHOR: Julie T. Cecere, DVM, MS, DACT
                                                queens.
           Prevention                                                            EDITOR: Michelle A. Kutzler, DVM, PhD, DACT
           •  Effective  physical  control  of  cycling  bitch   Client Education
            or queen during estrus            •  In  the  bitch  or  queen  not  intended  for
                                                breeding, ovariectomy or ovariohysterectomy





            Preputial Discharge



            BASIC INFORMATION                 •  Urinary tract infection (UTI)    DIAGNOSIS
                                              •  Prostatic disease
           Definition                                                            Diagnostic Overview
           Characterized by the presence of normal or   Clinical Presentation    The age of the animal helps differentiate
           abnormal secretions from the penile sheath   DISEASE FORMS/SUBTYPES   juvenile-onset from adult-onset forms of
           (prepuce).                         Juvenile onset versus adult onset  preputial discharge. In younger dogs, the forms
                                                                                 are generally benign and involve hormonal
           Synonym                            HISTORY, CHIEF COMPLAINT           imbalances rather than infectious processes.
           Penile discharge                   •  Preputial or penile discharge   Adult-onset forms are generally chronic and
                                              •  Excessive licking of prepuce    require a thorough diagnostic workup.
           Epidemiology                       •  ± Preputial discomfort/pain
           SPECIES, AGE, SEX                  •  ±  Visible lesions or abnormalities of the   Differential Diagnosis
           •  Canine, male                      penis/prepuce                    •  Clear/mucoid discharge
           •  Juvenile or adult               •  ± Urinary incontinence/distress (e.g.,   ○   Persistent penile frenulum
                                                stranguria, hematuria, pollakiuria)  ○   Hypospadias
           GENETICS, BREED PREDISPOSITION     •  ± Constipation, ribbon-like stool, tenesmus  ○   Traumatic penile adhesions
           Intact males and brachycephalic breeds tend                             ○   Phimosis
           to have more normal preputial discharge than   PHYSICAL EXAM FINDINGS   ○   Infectious (canine herpesvirus, calicivirus,
           other dogs.                        Depends on cause                       abnormal microbiologic flora)
                                              •  Discharge (smegma, mucoid, purulent, or   ○   Neoplasia
           RISK FACTORS                         hemorrhagic)                       ○   Hormonal imbalance (e.g., puberty,
           •  Anatomic abnormalities (acquired or congenital)  •  Preputial anatomic abnormalities  exogenous steroids)
           •  Hormonal imbalances (acquired or iatrogenic)  •  Preputial or penile lesions
           •  Poor hygiene/kennel management  •  Pain during manipulation
           •  Canine herpesvirus type 1 or Brucella canis   •  Atrophy of preputial opening
            infection                         •  Preputial mucosal vesicles (canine herpesvirus)
           •  Prostatic disease               •  Enlarged preputial/inguinal lymph nodes
           •  Hemostatic disorder (acquired vs. genetic)  •  Prostatomegaly
           •  Foreign body (e.g., grass awn)  •  Masses (transmissible venereal tumor [TVT])
                                              •  Systemic signs (e.g., lethargy, fever)
           CONTAGION AND ZOONOSIS             •  Petechiation  or  bruising  (hemostatic
           Preputial discharge may be contagious if caused by   defect)
           canine herpesvirus type 1 or B. canis (zoonotic).
                                              Etiology and Pathophysiology
           GEOGRAPHY AND SEASONALITY          •  Normal preputial discharge
           No geographic or seasonal trends have been   ○   Small amount of yellow-white smegma
           established.                       •  Abnormal preputial discharge
                                                ○   Clear/mucoid (can be copious): hormone
           ASSOCIATED DISORDERS                   imbalance in prepubertal dogs
           •  Balanitis (inflammation of the penis)  ○   Hemorrhagic: coagulopathy, trauma,
           •  Balanoposthitis (inflammation of the penis   neoplasia, prostatic or testicular disease  PREPUTIAL  DISCHARGE  Normal  preputial
            and prepuce)                        ○   Purulent: infection, foreign body  discharge in a prepubertal male dog.

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