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Proptosis of the Globe   823


            PROGNOSIS & OUTCOME                Technician Tips                    SUGGESTED READING
                                               •  Vaginal  cytology  swabs  should  be  gently   England GCW: Infertility in the bitch and queen.
  VetBooks.ir  •  If  estrus  persists,  increased  suspicion  of   •  Pyometra can be as pronounced as vaginal   In Noakes DE, et al, editors: Arthur’s veterinary   Diseases and   Disorders
                                                rolled, not smeared.
           •  Recurrence is possible, but prognosis is good
             if signs of diestrus follow treatment.
                                                                                   reproduction and obstetrics, Philadelphia, 2001,
                                                discharge or as subtle as depression or
                                                                                   Saunders, pp 639-670.
             neoplasia or abnormal karyotype yields a
                                                lethargy with a fever.
             poorer prognosis for subsequent fertility, and   •  Tumors should be staged with histopathology.  RELATED CLIENT EDUCATION
             an ovariohysterectomy is indicated.
                                               Client Education                   SHEETS
            PEARLS & CONSIDERATIONS            •  Train owners to recognize signs of estrus or   Consent to Perform Abdominal Ultrasound
                                                discuss outward signs of behavioral estrus   Consent to Perform Ovariohysterectomy (Spay),
           Comments                             for the bitch and queen.            Canine
           Although ovarian cancer is rare in the bitch   •  Clinicians and owners should discuss multiple   Consent to Perform Ovariohysterectomy (Spay),
           or queen, failure of medical treatment to end   benefits of spaying nonbreeding stock while   Feline
           signs of behavioral estrus or decrease circulating   young.
           estradiol concentrations greatly increases the   •  Recurrence is more likely in animals with   AUTHOR: Timothy Hazzard, DVM, PhD
           possibility of this diagnosis.       previous follicular cysts.        EDITOR: Michelle A. Kutzler, DVM, PhD, DACT
           Prevention
           In animals of nonbreeding stock, complete
           ovariohysterectomy  prevents  reproductive
           abnormalities and their sequelae.




            Proptosis of the Globe                                                                 Client Education
                                                                                                          Sheet


            BASIC INFORMATION                  •  Extraocular: other fractures (facial, axial, or   •  Buphthalmos  secondary  to  congenital,
                                                appendicular skeleton), neurologic deficits   primary, or secondary glaucoma (enlarged
           Definition                           from brain trauma, hypovolemic shock,   globe; eyelids in normal position; rarely
           Acute rostral displacement of the globe (exoph-  intrathoracic abnormalities (diaphragmatic   acute) (p. 387)
           thalmos), with caudal entrapment of eyelids  hernia, pulmonary contusions, hemothorax,
                                                pneumothorax)                     Initial Database
           Epidemiology                                                           •  Ophthalmic exam (p. 1137)
           GENETICS, BREED PREDISPOSITION      Etiology and Pathophysiology         ○   Pupillary light reflexes; a midrange,
           Brachycephalic breeds of dogs and cats are at   •  Force(s) applied to the head (e.g., trauma),   unresponsive pupil (direct and consensual)
           higher risk; however, if traumatic forces are   leading to rostral displacement of the globe   carries a grave prognosis for vision because
           sufficient, proptosis can occur in any breed   and caudal entrapment of eyelids  optic nerve stretching, avulsion or transec-
           of either species.                  •  In brachycephalic animals, the orbit encircles   tion is likely.
                                                a lesser proportion of the globe (i.e., is shal-  ○   Fluorescein dye application
           RISK FACTORS                         lower), allowing proptosis to occur despite   ○   Intraocular pressure (IOP > 30 mm Hg
           Traumatic forces to the head: mild for brachy-  a comparatively mild trauma.  with glaucoma; low [<10-15 mm  Hg]
           cephalic; moderate to severe for mesocephalic   •  The  medial  rectus  is  the  first  extraocular   with uveitis). IOP measurement should
           and dolichocephalic breeds           muscle to avulse during trauma, leading   be performed only after the globe has been
                                                to  lateral  strabismus.  Multiple  extraocular   replaced in the orbit, releasing the eyelids’
           ASSOCIATED DISORDERS                 muscle avulsions produce a greater degree   pressure on the globe.
           Retrobulbar mass or severe orbital abscess or   of proptosis, resulting in a grave prognosis   •  Chest  radiographs  if  hit  by  car,  signs  of
           cellulitis (p. 716) may predispose the eye to   for vision.              trauma beyond the face, and/or dyspneic
           proptosis.                                                             •  Skull radiographs if suspect orbital and/or
           Clinical Presentation                DIAGNOSIS                           skull fractures (e.g., extensive facial/cranial
                                                                                    trauma, bony crepitus, and neurologic
           HISTORY, CHIEF COMPLAINT            Diagnostic Overview                  compromise such as obtundation)
           Caused by peracute event, usually blunt head   History and physical exam provide the diagno-
           trauma (e.g., hit by car, fighting) or restraint   sis. Additional evaluation is directed at assessing    TREATMENT
           around neck (in severely brachycephalic dogs)  vision and identification of trauma to the rest
                                               of the body.                       Treatment Overview
           PHYSICAL EXAM FINDINGS                                                 Although the primary goal is to return the globe
           Exophthalmos with eyelids trapped caudal to   Differential Diagnosis   to its proper anatomic location, enucleation
           globe, along with any or all of the following:  •  Exophthalmos secondary to orbital abscess   may be preferable if there are grave prognostic
           •  Ocular: conjunctival hyperemia or hemorrhage,   (opening mouth may cause pain), benign   indicators for vision.
             corneal desiccation and/or ulceration, abnormal   or malignant orbital mass (opening mouth
             pupil size (constricted or dilated), intraocular   is rarely painful), and congenital vascular   Acute General Treatment
             inflammation and/or hemorrhage, ruptured   anomalies (opening mouth is rarely painful;   •  Hemodynamic, respiratory, and neurologic
             globe, avulsion of extraocular muscle(s) (mainly   forward displacement of globe that may   stabilization if trauma is severe
             medial  and/or ventral oblique recti), optic   be positional, but eyelids are in a normal   •  Keep cornea lubricated. If surgical correc-
             nerve rupture/transection, orbital fractures  position; rarely peracute) (p. 716)  tion is not immediately possible (e.g., grave
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