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824   Prostatic Enlargement (Noninfectious, Non-Neoplastic)


            anesthetic risk), hourly topical ointment   •  After repositioning and healing of the globe    PEARLS & CONSIDERATIONS
            application (alternating between bacitracin-  (days/weeks later), enucleation is still neces-  Comments
  VetBooks.ir  •  Place an Elizabethan collar to prevent self-  ○   Affected eye is blind and painful (e.g.,   •  True ocular emergency
                                                sary if
            neomycin-polymyxin  antibiotic  q  2h  and
            sterile lubricant q 2h) is recommended.
                                                                                 •  Avoid using topical corticosteroids (corneal
                                                  chronic uveitis, glaucoma, complex corneal
            inflicted trauma.
                                                                                   ulceration is common).
                                                  development of posttraumatic  ocular
           •  Reposition  the  globe,  with  patient  under   ulcer); critical in cats due to the risk of   •  A blind comfortable eye can have an excellent
            general anesthesia                    sarcoma (p. 559)                 cosmetic appearance.
            ○   Lateral canthotomy: 1-2 cm skin incision
              at the lateral canthus to relieve pressure   Possible Complications  Prevention
              on the eyelids                  •  Corneal ulceration              Permanent partial tarsorrhaphy (surgery to
            ○   Unroll eyelids and replace over globe  •  Keratoconjunctivitis sicca (KCS)  shorten length of eyelid opening) in brachy-
            ○   Simple interrupted skin sutures to close   •  Blindness          cephalic breeds of dogs
              lateral canthotomy              •  Repeat proptosis in brachycephalic breeds
            ○   Two to three horizontal mattress sutures   (soon after suture removal)  Technician Tips
              exiting meibomian gland openings (4-0 to   •  Strabismus (frequently lateral or dorsolateral   In the postoperative stage, avoid excessive
              6-0 suture material) with stents made of   due to avulsion of medial rectus or medial and   pressure around the neck to avoid recurrence
              Penrose drain or IV tubing to distribute   ventral oblique recti muscles, respectively)  (e.g., use harness instead of collar).
              tension evenly on upper and lower eyelids  •  Glaucoma
            ○   Removal of medial-most suture in 1-2   •  Uveitis                Client Education
              weeks and lateral sutures in 2-3 weeks,   •  Lagophthalmos (incomplete closure of eyelids   •  If  globe  is  replaced  but  remains  blind
              depending on resolution of exophthalmos  due to CN V or VII damage)  and painful in the postoperative stage,
            ○   Vision, tear production, cornea, and   •  Neurotrophic keratitis (damage to ophthal-  enucleation, or evisceration with intraocular
              intraocular structures (e.g., lens, retina)   mic branch of trigeminal nerve supplying   prosthesis if cornea and STT are normal,
              assessment within 2-3 weeks after surgery  cornea, such as in corneal denervation) with   is warranted.
           •  Enucleation  if  globe  is  ruptured,  optic   chronic corneal ulceration  •  Early enucleation of blind and painful eyes in
            nerve  is  transected,  and/or  three  or  more                        cats is done to prevent posttraumatic ocular
            extraocular muscles are avulsed   Recommended Monitoring               sarcoma.
                                              Recheck suture placement 24-48 hours post-
           Chronic Treatment                  operatively because eyelid swelling may have   SUGGESTED READING
           •  Topical atropine in medial canthus q 12h   dramatically improved, causing loosening of   Mandell DC, et al: Ophthalmic emergencies  Vet
            for 3 days                        sutures and risking corneal-suture contact.  Clin North Am Small Anim Pract 35:455, 2005.
           •  Topical antibiotic solution q 6h for 2 weeks
            (e.g.,  bacitracin-neomycin-gramicidin  or    PROGNOSIS & OUTCOME    RELATED CLIENT EDUCATION
            tobramycin)
           •  Nonsteroidal   antiinflammatory   drugs   •  Varies, depending on the extent of trauma   SHEETS
            (NSAIDs) systemically for 5-7 days. Dogs:   (e.g., hyphema is a poor prognostic sign)  Consent to Perform Enucleation
            carprofen 2.2 mg/kg PO q 12h; or meloxi-  •  Most affected eyes with mild trauma can be   Consent to Perform General Anesthesia
            cam 0.1 mg/kg PO q 24h. Cats: tolfenamic   salvaged.                 How to Administer Eye Medications
            acid 4 mg/kg SQ, IM, or PO q 24h for 3-5   •  Overall prognosis for vision varies  How to Assemble and Use an Elizabethan Collar
            days; robenacoxib 1 mg/kg PO q 24 h for   ○   Poor to grave (dolichocephalic breeds
            3 days.                               and cats; midrange unresponsive pupil;   AUTHOR: Chantale L. Pinard, DVM, MSc, DACVO
           •  Broad-spectrum systemic antibiotics for 5-7   marked proptosis [globe displaced several   EDITOR: Diane V. H. Hendrix, DVM, DACVO
            days (e.g., cephalexin 20 mg/kg PO q 8h)  centimeters rostral to the orbit])
           •  Elizabethan collar until suture removal  ○   Guarded (brachycephalic breeds)




            Prostatic Enlargement (Noninfectious, Non-Neoplastic)                                  Client Education
                                                                                                         Sheet

                                              Epidemiology
            BASIC INFORMATION                                                      described only in association with neoplastic
                                              SPECIES, AGE, SEX                    lesions, bacterial prostatitis, and prostatic
           Definition                         •  BPH is observed only in dogs (and men).   abscess.
           Prostatic cell hypertrophy and hyperplasia are   BPH  is  a  normal  age-related  change  in
           ongoing processes with progressive expansion   intact male dogs (80% of intact dogs > 5   GENETICS, BREED PREDISPOSITION
           over time. Noninfectious/non-neoplastic prostate    years and 95% > 9 years of age). Histologic   Prostatic size correlates with body weight and
           enlargement should be considered a normal   evidence of BPH can be encountered at a   breed. Scottish terriers are reported to have
           physiologic process without pathologic conse-  young age, with a reported 16% prevalence   prostates that are four times larger than those
           quences for most intact dogs. Loss of androgen   among 2-year-old, intact male beagles.   from other breeds of similar weights. German
           influence after castration or by pharmacologic   However, the true prevalence of BPH is   shepherds  and  Doberman  pinschers  have
           blockade causes regression of the prostate to   difficult to determine. A study focusing   a  higher  reported  incidence  of  all  prostatic
           an immature, rudimentary state.      on dogs that died of diseases unrelated to   diseases.
                                                the  prostate  found  a  45%  prevalence  of
           Synonyms                             subclinical BPH.                 RISK FACTORS
           Prostatomegaly, benign prostatic hyperplasia   •  Diseases  of  the  prostate  gland  are  rare  in   Prolonged androgen exposure (endogenous or
           (BPH), cystic BPH                    cats and prostatomegaly in cats has been   exogenous)

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