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918   Sinusitis and Other Sinus Disorders


           •  Tumors associated with frontal sinusitis: older   Etiology and Pathophysiology  •  Submandibular lymph node aspirates (bilat-
            dogs                              •  Sinusitis  is  usually  secondary  to  another   eral) may help detect metastatic neoplasia.
  VetBooks.ir  •  Chronic  idiopathic  sinusitis:  young  to   (see  Associated  Disorders)  that  disrupts    Advanced or Confirmatory Testing
                                                primary nasal or  frontal  sinus disease
           •  Aspergillosis: young adults
                                                                                 •  CT and/or MRI of the nasal cavities and
                                                normal nasal/sinus anatomy and impairs
            middle-aged dogs
           •  Cilary dyskinesia: young dogs
                                                drainage.
           •  Trauma: any age                   mucociliary clearance or obstructs mucus   sinuses  can  differentiate  neoplasia,  fungal
                                                                                   rhinitis, and dental disease with more
                                              •  Due  to  physical  continuity  between  the   accuracy than plain radiographs but cannot
           GENETICS, BREED PREDISPOSITION       chambers, frontal sinus tumors can extend   confirm  the  diagnosis  in  all  cases.  Biopsy
           •  Cats:  brachycephalic  breeds,  especially     into the nasal cavity, and nasal tumors can   with histopathology is frequently necessary.
            Persian and Himalayan for upper respira-  extend in the frontal sinus.  •  The frontal sinus can be examined by direct
            tory tract aspergillosis (both sinonasal and     •  Mycotic  sinusitis  and  rhinitis  can  affect   rhinoscopy in some dogs, but access to and
            sino-orbital forms), any breed for other   the nasal cavity and sinus individually  or   visualization of the frontal sinus is often pos-
            diseases                            in combination. Periorbital involvement is   sible only in animals with severe turbinate
           •  Dogs:  primarily  dolichocephalic  breeds   seen in cats.            destruction.
            for  frontal  sinusitis  associated  with   •  Chronic lymphoplasmacytic inflammation in   •  Trephination of the frontal sinus for exam
            tumors, aspergillosis, or chronic idiopathic    dogs can be a sequela to many other sinonasal   and  biopsy  may  be  necessary  to  confirm
            sinusitis                           diseases (p. 890).                 the presence of neoplasia, fungal rhinitis,
                                              •  Chronic lymphoplasmacytic rhinosinusitis in   or  inflammation,  especially if  disease  is
           ASSOCIATED DISORDERS                 cats can be a sequela to bacterial, viral (feline   confined to the frontal sinus. Trephination
           •  Nasal tumors                      upper respiratory tract infection complex),   may also have therapeutic value for cases of
           •  Nasal aspergillosis               as well as mycotic infections.     fungal rhinitis in dogs (p. 81).
           •  Chronic  idiopathic  or  lymphoplasmacytic   ○   As in dogs, the condition can be idiopathic
            rhinosinusitis                        in cats, possibly  related to an allergic      TREATMENT
           •  Nasal or frontal sinus trauma       cause.
           •  Abscessation  of  roots  of  the  upper  fourth   •  Primary bacterial rhinitis is rare, with most   Treatment Overview
            premolar  (apical  dental  abscess),  causing   bacterial infections occurring secondary to   When possible, the best opportunity for resolu-
            maxillary sinus empyema             an underlying disease process. The exception   tion of sinusitis is treatment of the underlying
           •  Feline herpesvirus (rhinotracheitis)  is bacterial rhinitis associated with ciliary   primary nasal disease.
                                                dyskinesia, which results in recurrent bouts
           Clinical Presentation                of sinusitis, rhinitis, and pneumonia due to   Acute General Treatment
           DISEASE FORMS/SUBTYPES               defective mucociliary clearance.  •  Treatment of the underlying disease.
           See Associated Disorders above.                                         ○   Fungal  sinusitis/rhinitis:  antimycotic
                                               DIAGNOSIS                             therapy (p. 81)
           HISTORY, CHIEF COMPLAINT                                                ○   Frontal sinus tumors: radiation therapy,
           •  Nasal discharge                 Diagnostic Overview                    and occasionally, surgical resection
           •  Intermittent sneezing           Sinus diseases are generally associated with nasal   ○   Traumatic  injuries  causing  fractures  of
           •  Focal facial swelling or deformity (tumor,   diseases and probably secondary to nasal disease   the frontal bone: removal of bone frag-
            trauma)                           in most cases.                         ments in the frontal sinus and possibly
           •  Signs related to local pain                                            reconstruction; check patency of the
            ○   Dullness or lethargy          Differential Diagnosis                 nasofrontal ostium (nasofrontal opening);
            ○   Decreased movements of the head  Nasal diseases of various origins:  broad-spectrum antibiotics
            ○   Anorexia                      •  Fungal rhinitis                   ○   Apical dental (tooth root) abscess: surgical
                                              •  Nasal neoplasia                     extraction of the tooth, including roots,
           PHYSICAL EXAM FINDINGS             •  Dental disease/dental root infection (maxil-  or endodontic treatment; broad-spectrum
           •  Unilateral nasal discharge of variable nature:   lary sinus)           antibiotics
            mucoid, mucopurulent, or blood tinged;   •  Foreign bodies           •  For  acute  infection,  as  well  as  in  chronic
            often bloody with nasal neoplasia  •  Lymphoplasmacytic rhinitis       idiopathic inflammation with episodes
           •  Diminished airflow through nasal passages/  •  Nasal mites           of secondary bacterial infections, oral or
            nares if nasal cavity affected, except aspergil-  •  Chronic viral upper respiratory tract infection   injectable antibiotics (amoxicillin 20 mg/kg
            losis (increased airflow)           in cats                            PO q 8h, cefadroxil 20 mg/kg PO q 8h, or
           •  Focal  swelling,  firm  enlargement,  facial                         amoxicillin-clavulanate 15 mg/kg PO q 12h)
            deformity, and/or pain with atrophy or lysis   Initial Database        and possibly mucolytics may be needed.
            of the frontal or nasal bones:    •  For  some  cases,  plain  radiographs  of  the   ○   The  frontal  sinus  is  a  combination  of
            ○   Depressions or defects in frontal/nasal   nasal cavities, sinuses, and dental roots can   several large cavities surrounded by bone;
              bone integrity from osteolysis may be   be helpful in the diagnosis of trauma or   systemically administered drugs often do
              noted during palpation.           structural lesions secondary to neoplasia,   not achieve high concentrations in the
            ○   Dogs  with  maxillary  sinusitis  from    fungal rhinitis/sinusitis, and dental disease   sinus. Even very high doses of highly
              fourth premolar tooth root abscessation   but cannot discriminate among the various   soluble drugs, preferred for systemic
              may have a swelling or fistulous tract     causes of nasal/sinus disease not involving   therapy,  may not  reach adequate  con-
              and drainage ventral to the eye on affected   structural changes. Generally considered both   centrations throughout the entire sinus
              side.                             poorly sensitive and poorly specific.  cavity.
           •  Enlargement  of  submandibular  lymph   •  CBC,  serum  biochemical  profile,  and   ○   Effect of drug nebulization is unproved;
            nodes is possible. Both lymph nodes may   urinalysis are often unremarkable.  the amount of drug delivered into the
            be affected due to overlapping drainage   •  For cases in which there is swelling or lysis   frontal sinus is unknown.
            territories (lymphosomes).          (which can be palpable) of nasal/facial bones
           •  Percussion  of  the  sinus  may  induce    or the frontal sinus area, fine-needle aspira-  Chronic Treatment
            pain  or be associated  with  reduced    tion (FNA) cytology can show neoplasia or   In cases of concomitant nasal disease with loss
            resonance.                          inflammation.                    of the protective filter provided by normal
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