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Smoke Inhalation   919


                                                                                   PEARLS & CONSIDERATIONS

  VetBooks.ir                                                                     Comments                            Diseases and   Disorders
                                                                                  •  In acute cases, quickly find the cause using
                                                                                    appropriate diagnostic tests, and promptly
                                                                                    treat to avoid chronic irreversible sequelae.
                                                                                  •  When sinusitis is related to extension of nasal
                                                                                    disease, it is often a chronic condition with
                                  *                                                 consequent remodeling, and cure is rare;
                                                                                    secondary  bacterial  infections  can  always
                                                                                    occur.
                                                                                  Technician Tips
                                                                                  Although of low diagnostic yield, cytologic
           SINUSITIS AND OTHER SINUS DISORDERS  Endoscopic view of the frontal sinus of a dog. A large,   exam of nasal exudate can occasionally identify
           smooth convex mass occupies the center of the image (arrows), and its appearance strongly suggests neoplasia.   another underlying cause (e.g., cryptococcosis,
           An adjacent blood vessel is seen (asterisk).                           rarely nasal neoplasia) of nasal cavity disease.
                                                                                  Culture of nasal exudate is not recommended.
           turbinates  and  decreased  mucociliary  clear-  aspergillosis because the latter must be treated
           ance  along  the  distal  nasal  cavity,  recurrent   with antifungal agents.  Client Education
           secondary  bacterial  infections  are  common                          Treatment must be repeated for relapses, which
           and are treated each time with antibiotics    PROGNOSIS & OUTCOME      are common in chronic idiopathic sinusitis.
           and mucolytics, preferably using intranasal                            The disease rarely totally resolves, and often,
           administration.                     •  Prognosis  and  outcome  depend  on  the   mild clinical signs persist despite treatment.
                                                cause, whether the cause can be eliminated   If  severe  signs  persist,  repeating  a  complete
           Possible Complications               or treated, and whether there is chronic,   diagnostic  evaluation  is indicated,  with  the
           In animals with chronic sinusitis, repeated   irreversible damage to the turbinates and   intent of identifying an underlying cause.
           episodes of bacterial infection can be expected.  sinus mucosa.
                                               •  Poor  for  most  patients  with  frontal  sinus   SUGGESTED READING
           Recommended Monitoring               tumors, which are usually malignant  Venker-van Haagen AJ, et al: Disease of the nose and
           Monitoring  depends  on  the  cause  of  the   •  Favorable prognosis for the sinonasal form   nasal sinuses. In Ettinger SJ, et al, editors. Textbook
           condition and persistence of clinical signs. For   of  feline  aspergillosis  (SNA)  and  poorer   of internal veterinary medicine, St. Louis, 2010,
           example, in lymphoplasmacytic inflammation of   prognosis for the more invasive sino-orbital   Elsevier, pp 1030-1040.
           the frontal sinus after treatment of aspergillosis,   form, the most common form (65% of cases)  AUTHORS: Cécile Clercx, DVM, PhD, DECVIM; Frédéric
           diagnostic workup is warranted in cases with   •  Cure of chronic sinusitis is rarely achieved,   Billen, DVM, MS, PhD, DECVIM
           recurrence of severe clinical signs to differentiate   but response to ongoing therapy is generally   EDITOR: Megan Grobman, DVM, MS, DACVIM
           secondary bacterial infection from recurrence of   good.




            Smoke Inhalation                                                                       Client Education
                                                                                                          Sheet

            BASIC INFORMATION                  secondary bacterial pneumonia, systemic inflam-  •  Mentation  and  motor  dysfunction  may
                                               matory response syndrome (SIRS)      include ataxia, weakness, depression, stupor,
           Definition                                                               or coma.
           Injury to the respiratory system results   Clinical Presentation       •  Mucous membranes may be hyperemic (due
           from breathing harmful gases, vapors, and   DISEASE FORMS/SUBTYPES       to  carboxyhemoglobin  [COHb],  cyanide
           particulate  matter  contained in smoke.   Inhalation injury generally manifests in three   [CN], or vasodilation), pale, or cyanotic.
           Neurologic dysfunction and burns may occur    clinical stages:         •  Dermatologic findings include smoky smell,
           concurrently.                       •  Hypoxic injury                    singed or burnt hair and skin, soot, or skin
                                               •  Neurologic compromise             lacerations.
           Synonyms                            •  Secondary lung injury           •  Altered mental status, abnormal respiratory
           Smoke exposure, smoke intoxication                                       effort, and hypothermia may be associated
                                               HISTORY, CHIEF COMPLAINT             with a higher blood level of CO.
           Epidemiology                        •  Complaint  of  respiratory  difficulties  after
           SPECIES, AGE, SEX                    smoke inhalation                  Etiology and Pathophysiology
           Any animal can suffer smoke inhalation.  •  Weakness, stupor, or coma after rescue  Causes of respiratory injury:
                                                                                  •  Thermal  damage  is  usually  limited  to  the
           RISK FACTORS                        PHYSICAL EXAM FINDINGS               upper-airway mucosa, owing to rapid heat
           Exposure to closed-space fires      •  Respiratory  distress,  coughing,  tachypnea,   dissipation. Steam, soot (particles < 2.5 mm),
                                                short or shallow respirations, harsh or    and volatile and explosive gases, however, may
           GEOGRAPHY AND SEASONALITY            moist airway sounds, crackles, wheezes,    also cause thermal injury to lower airways.
           More residential fires in winter     and loud laryngeal or tracheal sounds;    •  Asphyxiation
                                                in milder cases, signs may be limited to     ○   Atmospheric  oxygen  deficit  due  to
           ASSOCIATED DISORDERS                 the  nasal  cavity  (inflammation-induced    combustion
           Carbon  monoxide  (CO)  intoxication,  acute   nasal congestion, obstruction to nasal   ○   CO toxicosis: tissue hypoxia from COHb
           respiratory distress syndrome (ARDS), burns,   airflow).                   formation and subsequent decrease in the
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