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Tonsillar Disorders   979


           •  Cholestyramine  300 mg/kg  PO  q  6h   ○   Fragments  bind  directly  to  digoxin,    PEARLS & CONSIDERATIONS
             enhances elimination of digitoxin in humans   rendering them unavailable to interact   Comments
  VetBooks.ir  •  Non–calcium-containing IV fluids correct   Drug Interactions    •  Eggs may be more toxic than adult toads.  Diseases and   Disorders
                                                  at the binding sites.
             and may be tried.
                                                                                  •  Tadpoles are similar in toxicity to adults.
             potassium disorders, if present.
           •  Maropitant 1 mg/kg SQ
                                                concentration.
                                                                                    because it can worsen tachyarrhythmias.
           •  Seizures: diazepam 0.5-1 mg/kg IV  •  Amiodarone  increases  serum  glycoside   •  Do not use atropine to treat hypersalivation
           •  Arrhythmias: treat as appropriate (pp. 1033   •  Calcium channel blockers, beta-blockers: use
             and 1457)                          only when needed, can have additive effects   Prevention
             ○   Atropine  0.02-0.04 mg/kg  IV  for   on the AV node              Try to limit pet access in areas with toads during
               bradycardia                     •  Calcium increases arrhythmias.  peak toad activity.
             ○   Propranolol  0.02-0.06 mg/kg  IV  for
               supraventricular arrhythmias, or  Possible Complications           Technician Tips
             ○   Esmolol (dogs) 0.25-0.5 mg/kg IV over   •  Concern  for  renal  injury  with  prolonged   Closely monitor arrhythmias because they can
               1-2  minutes,  then  25-200 mcg/kg/min   hypotension               change frequently.
               constant-rate infusion (CRI)    •  Potential for permanent myocardial damage
             ○   Phenytoin 2 mg/kg up to 10 mg/kg IV                              Client Education
               (dogs)  for  ventricular  arrhythmias  (dis-  Recommended Monitoring  Secretions from the skin can contaminate
               rupts reentrant pathways and improves   •  ECG, BP, oxygen saturation  water bowls. Do not leave full water bowls
               conduction through AV node), or  •  Neurologic status              out overnight in areas where the most toxic
             ○   Lidocaine  2 mg/kg  IV  up  to  8 mg/kg,   •  Potassium          toads live.
               25-80 mcg/kg/min  CRI  (dogs);  0.25-
               0.5 mg/kg IV (cats)              PROGNOSIS & OUTCOME               SUGGESTED READING
           •  Oxygen (p. 1146)                                                    Peterson ME, et al: Toads. In Peterson ME, et al,
           •  Antidote: digoxin Fab fragments (Digibind)   •  Good if signs are just limited to mild GI;   editors: Small animal toxicology, ed 3, St. Louis,
             can be given in severe cases. Start with 1-2   guarded if cardiac signs develop  2013, Saunders, pp 833-839.
             vials administered slowly over 30 minutes;   •  Signs last 1-2 hours if toad is licked/mouthed   AUTHOR & EDITOR: Tina Wismer, DVM, MS, DABVT,
             response occurs within 20-90 minutes (very   and up to 36 hours if ingested.  DABT
             expensive: $2000+).





            Tonsillar Disorders                                                                    Client Education
                                                                                                          Sheet


            BASIC INFORMATION                  coughing, ptyalism, stridor, and inappetence.   vomiting,  regurgitation,  or  coughing;  it
                                               The  clinical  signs  of  the  underlying  disease   may also result from chronic pharyngitis
           Definition                          may often be more clinically significant than   secondary to elongated soft palate, immu-
           Abnormal structure or function of the palatine   the signs attributable to tonsillar enlargement.  nosuppression from feline immunodeficiency
           tonsils usually manifests as increased size, often                       virus (FIV), chronic contamination of the
           with protrusion from the tonsillar fossa.  PHYSICAL EXAM FINDINGS        oropharynx  with  pathogenic  bacteria  in
                                               •  Bilaterally or unilaterally enlarged palatine   cases  of  chronic  periodontal  disease,  or
           Synonym                              tonsils; with tonsillitis, the tonsils are often   licking of distant infected sites such as skin
           Palatine tonsillar disorder          bright red and protrude from the tonsillar   or anal sacs.
                                                crypts. There may be petechiae or a purulent   •  Swallowed foreign bodies such as grass awns
           Epidemiology                         exudate on the tonsils or in the tonsillar   or wood splinters may become lodged in the
           SPECIES, AGE, SEX                    crypts.                             tonsillar crypt.
           •  Occasionally seen in dogs; less frequent in   •  Fever is common with infectious disease.  •  Tonsillar cyst: embryonic remnant
             cats of either sex                •  Inspect for evidence of infection or inflam-  •  Neoplasia: squamous cell carcinoma (SCC) or
           •  Acute tonsillitis appears to be more frequent   mation that could cause secondary tonsillar   lymphoma may develop from the epithelial
             in animals < 1 year of age.        reactivity  by  licking  behavior  (e.g.,  anus,   or  lymphoid  components  of  the  tonsils,
                                                external genitalia) and the teeth/gums.  respectively.
           CONTAGION AND ZOONOSIS
           •  Group A Streptococcus pyogenes (“strep throat”   Etiology and Pathophysiology   DIAGNOSIS
             in humans) does not cause signs of tonsillitis   •  The palatine tonsils are sentinels for exposure
             in dogs or cats.                   to antigens that enter through the mouth   Diagnostic Overview
           •  Rates  of  infection  in  dogs  or  cats  from   and nose. Unlike lymph nodes, they have no   Most cases  of bilateral  tonsillar  enlargement
             contact with infected humans appear low; in   afferent drainage region, and reactive tonsillar   are benign and secondary to processes such as
             rare circumstances, infected dogs or cats not   enlargement arises from exposure through   licking infected material. The diagnostic goal
             showing clinical signs may serve as a source   the oral cavity.      is to rule out neoplasia. If a single tonsil is
             of reinfection for humans in the household.  •  Primary tonsillitis: bacterial or viral coloniza-  irregular and enlarged, suspect SCC or foreign
                                                tion of the lymphatic tissue of the tonsils.   body. If both tonsils are enlarged along with
           Clinical Presentation                The tonsils are a common portal of entry   other lymphoid tissues such as peripheral lymph
           HISTORY, CHIEF COMPLAINT             for enteric bacteria and viruses.  nodes, suspect lymphoma. Suspected neoplastic
           Tonsillar enlargement often is an incidental   •  Secondary  tonsillitis  results  from  chronic   cases can be confirmed with fine-needle aspira-
           finding; signs may include dysphagia/retching,   pharyngeal  irritation,  such  as  recurrent   tion (FNA) or biopsy.

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