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80    Aseptic Necrosis of the Femoral Head


           •  Abdominal radiographs: limited utility due   Acute General Treatment   PEARLS & CONSIDERATIONS
            to lack of serosal detail         If abdominal distention due to fluid accumula-  Comments
  VetBooks.ir  Advanced or Confirmatory Testing  therapeutic abdominocentesis or  adominal   •  Excessive fluid drainage may promote further
                                              tion is severe enough to compromise respiration,
           •  Abdominal ultrasonography: evaluate hepatic
            and renal parenchyma
                                                                                   effusion and dehydration.
                                              drainage may be indicated (p. 1056).
                                                                                   unless due to heart failure.
           Guided by initial findings         Chronic Treatment                  •  Lasix has no role in management of ascites
           •  If evidence of hypoalbuminemia and concur-  Treatment aimed at underlying disorder
            rent hyperglobulinemia, intestinal biopsies                          Prevention
            may  be  indicated  to  determine  cause  of   Nutrition/Diet        Ectoparasite and endoparasite prophylaxis
            protein-losing enteropathy (p. 600).  Protein-losing  enteropathy,  protein-losing
           •  If  hypoalbuminemia  and  proteinuria,     nephropathy, and cardiac disease have unique   Technician Tips
            urine protein: creatinine ratio (p. 1391)   nutritional requirements.  •  Animals with severe ascites may have diffi-
            indicated                                                              culty breathing, especially when restrained
           •  If murmur, jugular pulses, or cardiovascular   Recommended Monitoring  while lying on their side or back (e.g., during
            abnormalities detected, echocardiogram (p.   Resting respiratory rate, body weight; abdomi-  abdominal ultrasound).
            1094) and heartworm antigen test (p. 1350)   nal circumference can be used to estimate   •  Avoid  blind  cystocentesis  in  animals  with
            indicated                         change in volume of ascites fluid.   ascites.
            TREATMENT                          PROGNOSIS & OUTCOME               SUGGESTED READING
                                                                                 Chambers G: Abdominal enlargement. In Ettinger
           Treatment Overview                 Variable depending on cause          SJ, et al, editors: Textbook of veterinary internal
           Depends on underlying cause                                             medicine, ed 8, St. Louis. 2017, Elsevier, pp
                                                                                   144–148.
                                                                                 AUTHOR: Aida I. Vientós-Plotts, DVM
                                                                                 EDITOR: Leah A. Cohn, DVM, PhD, DACVIM



            Aseptic Necrosis of the Femoral Head                                                   Client Education
                                                                                                         Sheet


            BASIC INFORMATION                                                    •  Other  causes  of  rear  limb  lameness  (e.g.,
                                              PHYSICAL EXAM FINDINGS               patellar luxation, stifle injury)
           Definition                         •  Pain on extension and flexion of the affected
           A painful hip condition caused by interruption of   hip joint(s)      Initial Database
           blood supply to the proximal femoral epiphysis,   •  Affected limb may be non–weight-bearing  •  Physical examination of affected and unaf-
           producing bone necrosis and collapse of the   •  Muscle atrophy in the affected limb(s)  fected hind limb, with special emphasis on
           articular cartilage and eventually hip osteoarthritis.   •  Crepitus unusual but may be present in dogs   the hip joints
           The problem is unilateral in about 80% of cases.  that have developed degenerative joint disease  •  Hip  radiographs  (lateral  and  ventrodorsal
                                                                                   projections)
           Synonyms                           Etiology and Pathophysiology         ○   Early stage: femoral head lucency
           Legg-Calvé-Perthes (LCP) disease, Legg-Perthes   •  Cause and pathogenesis are unknown.  ○   Later stages: femoral head deformity and
           disease, Perthes disease, avascular or aseptic   •  The primary lesion appears to be ischemic   degenerative changes in the hip
           necrosis of the femoral head         injury causing necrosis of the bone of the
                                                femoral capital epiphysis.       Advanced or Confirmatory Testing
           Epidemiology                       •  Dead  bone  trabeculae  collapse,  forming   Computed tomography, magnetic resonance
           SPECIES, AGE, SEX                    hollow spaces that cause loss of support to   imaging,  nuclear  scintigraphy:  not  routinely
           •  Small-breed dogs                  overlying articular cartilage. Trabeculae that   required but could be useful when radiographic
           •  Mean  age  of  onset  of  clinical  signs  is  7   form in their place are abnormally thin and   changes are not yet apparent
            months, with a range of 3-11 months.  unable to support normal loads.
           •  This disease has not been reported in cats.  •  Subsequent weight bearing causes collapse    TREATMENT
                                                of the femoral head and deformation  of
           GENETICS, BREED PREDISPOSITION       the cartilage, leading  to development of   Treatment Overview
           •  Autosomal recessive trait in West Highland   osteoarthritis.       Treatment is aimed at restoration of normal,
            white and Manchester terriers, miniature                             pain-free activity.
            poodles                            DIAGNOSIS
           •  Other  commonly  affected  breeds  include                         Acute General Treatment
            Yorkshire, Lakeland, and cairn terriers;   Diagnostic Overview       •  Medical  management  (analgesics,  exercise
            miniature pinschers; toy poodles; Australian   Signalment, physical findings, and radiographic   modification; one report of successful use
            shepherds; Chihuahuas; dachshunds; Lhasa   confirmation make the diagnosis.  of an Ehmer sling): return to pain-free
            apsos; pugs.                                                           function in about 25% of cases
                                              Differential Diagnosis             •  Surgical intervention
           Clinical Presentation              •  Capital physeal or femoral neck fractures  ○   Femoral head and neck excision (FHNE)
           HISTORY, CHIEF COMPLAINT           •  Hip dysplasia                       or femoral head ostectomy (FHO) is the
           Slowly progressing or acute onset of hip pain/  •  Coxofemoral luxation   most common treatment.
           lameness during the first year of life  •  Septic arthritis of the hip  ○   Total hip replacement (THR)

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