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Aspergillosis   81


                                                                                    a nonpainful pseudoarthrosis with an ade-
                                                                                    quate range of motion.
  VetBooks.ir                                                                       due to a femoral neck remnant and often   Diseases and   Disorders
                                                                                  •  Continued lameness after FHNE is usually
                                                                                    resolves if this remnant is removed.
                                                                                  •  Chronic femoral capital physeal fractures (in
                                                                                    cats and dogs) can be confused with aseptic
                                                                                    necrosis  on  radiographs,  but  the  cause  is
                                                                                    different.

                                                                                  Technician Tips
                                                                                  •  Postoperative radiographs should include an
                                                                                    extended-limb  ventrodorsal  view  and  a
                                                                                    frog-leg view with femurs pulled cranially
                                                                                    (parallel to the spine) to highlight femoral
           ASEPTIC NECROSIS OF THE FEMORAL HEAD  Ventrodorsal view of the coxofemoral joints of a 10-month-old   neck remnants.
           pug with left hindlimb lameness and hip joint pain. Note the bone deformation of the left femoral head (arrow)   •  Leash-controlled  walking  and  range-of-
           compared with the normal right joint.                                    motion exercises should be started immedi-
                                                                                    ately after surgery to encourage normal limb
           Chronic Treatment                   Possible Complications               use.
           •  The same surgical options can be used in   •  Pain  due  to  inadequate  removal  of  the   Client Education
             chronic cases, but postoperative recovery may   femoral neck in FHNE  •  Breeders of dogs at risk should be warned
             be less satisfactory due to learned behavior   •  Poor limb usage from inadequate physical   that this condition is heritable. Affected
             (avoidance of use of the affected leg) or   rehabilitation after FHNE  animals should be removed from the breeding
             chronic muscle atrophy.                                                pool.
           •  If surgery is not done or lameness resolves   Recommended Monitoring  •  For  postoperative  care  at  home,  provide
             incompletely, one of the following nonster-  •  Postoperative radiographs to evaluate FHNE   client with client education sheet: How
             oidal antiinflammatory drugs (NSAIDs) can   osteotomy                  to Perform Range-of-Motion Exercises
             be given on an intermittent or (if necessary)   •  Monthly physical examinations to evaluate   (www.ExpertConsult.com).
             daily basis:                       limb function until normal
             ○   Carprofen 2.2 mg/kg PO q 12h or 4.4 mg/                          SUGGESTED READING
               kg PO q 24h; or                  PROGNOSIS & OUTCOME
             ○   Deracoxib 1-2 mg/kg PO q 24h; or                                 Towle Millard HA, et al: Miscellaneous orthopedic
             ○   Meloxicam 0.1 mg/kg PO q 24h  •  Lameness resolves in > 80% of cases after   conditions. In Johnston SA, et al, editors: Veterinary
                                                                                   surgery: small animal, St. Louis, 2018, Elsevier, p
                                                FHNE or THR.                       1309.
           Nutrition/Diet                      •  Lameness resolves in < 25% of cases with
           •  Aim to maintain normal body condition.  medical treatment alone.    Reproduced from the third edition in modified
                                                                                  form.
           •  Dietary supplements do not appear to be
             helpful.                           PEARLS & CONSIDERATIONS           THIRD EDITION AUTHORS: D. Michael Tillson, DVM, MS,
                                                                                  DACVS; Katrin Saile, DVM, MS, DACVS
           Drug Interactions                   Comments                           AUTHOR & EDITOR: Kathleen Linn, DVM, MS, DACVS
           •  Concurrent administration of glucocortico-  •  Radiographic changes are subtle early in the
             steroids and NSAIDs can result in severe   course of the disease; serial radiography may
             gastrointestinal  irritation, ulceration, and   be helpful in diagnosis.
             perforation.                      •  Physical  rehabilitation  is  important  for
           •  Chronic NSAID treatment can exacerbate   obtaining the best results after FHNE.
             liver or renal dysfunction.        Range-of-motion exercises, swimming, and
                                                limited weight-bearing exercises help create



            Aspergillosis                                                                            Bonus Material
                                                                                                          Online


            BASIC INFORMATION                  GENETICS, BREED PREDISPOSITION     •  Sinonasal:  other  primary  nasal  disease,
                                               •  Systemic aspergillosis: German shepherd dogs   immunoglobulin A deficiency, prolonged
           Definition                           overrepresented                     antibiotic use, nasal conformation
           Regional or disseminated infection with     •  Sinonasal  aspergillosis:  medium-  to  large-
           the opportunistic hyphal fungus  Aspergillus    breed, dolichocephalic dogs overrepresented.   CONTAGION AND ZOONOSIS
           spp                                  Conversely, brachycephalic cat breeds (e.g.,   Aspergillosis is an opportunistic infection; it
                                                Persian) are predisposed to upper respiratory   is not zoonotic or contagious.
                                                aspergillosis (sinonasal or sino-orbital).
           Epidemiology                                                           ASSOCIATED DISORDERS
           SPECIES, AGE, SEX                   RISK FACTORS                       •  Systemic: discospondylitis
           Dogs more commonly affected than cats; often   •  Systemic/disseminated: immunosuppression,   •  Sinonasal: chronic rhinitis; fungal sinusitis
           middle-aged adults                   primary immune deficiencies

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