Page 2008 - Cote clinical veterinary advisor dogs and cats 4th
P. 2008

Upper Airway Obstruction   1005


           •  Subglottic  structures:  tracheal  collapse   deliberate inspiration and rapid exhalation),   ○   Anxiolytic drugs (e.g., trazodone 2-7 mg/
             (p. 194), FB, tracheal neoplasia, tracheal   often with the point of stridor audible in   kg PO q 12h)
  VetBooks.ir  to the airway (e.g., thyroid carcinoma,   lesion. Stertor, in nonbrachycephic breeds, may   Nutrition/Diet  Diseases and   Disorders
             hypoplasia, trauma. Mass lesions external
                                               the upper airway, helps localize the anatomic
                                               be indicative of altered upper airway airflow.
             cervical abscess) can cause narrowing or
                                                                                  Weight loss diet may be indicated for long-term
             collapse of the airway.
                                               Signalment, history, and exam findings usually
                                               allow a refined differential diagnosis. Oral   treatment of obesity.
           HISTORY, CHIEF COMPLAINT            and laryngeal exam, diagnostic imaging, and   Behavior/Exercise
           •  Loud breathing (new stertor or stridor) is   endoscopy confirm the site (and sometimes   Avoid heat stress.
             most consistent finding. Respiratory effort   nature) of the obstruction.
             may be mild or severe. Acute distress after                          Possible Complications
             playing with an object (e.g., ball) suggests   Differential Diagnosis  Recurrence of clinical signs, aspiration pneu-
             FB obstruction. Neoplasia may manifest as   Occasionally, pleural effusion in cats mimics   monia, noncardiogenic pulmonary edema, and/
             progressive dyspnea. Laryngeal paralysis often   upper respiratory obstruction.  or respiratory arrest
             is accompanied by a change in the sound
             of the bark (dysphonia). Clinical signs often   Initial Database     Recommended Monitoring
             are exacerbated by exercise, excitement, or   •  Oral/laryngeal  exam  under  sedation   Monitor respiratory rate/effort, oxygenation,
             on a warm day.                     is the most important diagnostic test     and ventilatory status.
           •  Foreign  object  (e.g.,  ball,  marble,  acorn)   (p. 1125).
             aspiration may be witnessed, although the   ○   Be prepared for an emergent intubation    PROGNOSIS & OUTCOME
             mistaken belief that an FB has been aspi-  or tracheostomy (and possibly positive-
             rated is a common error that some clients   pressure ventilation if noncardiogenic   •  Depends  on  the  underlying  problem  and
             believe passionately (“something stuck in the   pulmonary edema is present (pp. 1166     severity of clinical signs
             throat”) even when the problem is clearly   and 1185).               •  Prognosis worse for cases with noncardiogenic
             different  (e.g.,  pulmonary  edema,  pleural    ○   Doxapram 2.2 mg/kg IV can stimulate   pulmonary edema or pneumonia
             effusion).                           ventilation  during  exam  but  may
                                                  result in glottic constriction requiring      PEARLS & CONSIDERATIONS
           PHYSICAL EXAM FINDINGS                 intubation.
           •  Noisy,  stridorous  (laryngeal  or  subglottic)   •  Ancillary testing includes radiographs (cervi-  Comments
             or stertorous (nasal or nasopharyngeal)   cal and thoracic), CBC, serum biochemistry   •  Up to one-half the diameter of the airway
             breathing                          profile, and evaluation of oxygenation   can be compromised without obvious clinical
             ○   Typically exaggerated inspiratory effort  (pulse oximetry or arterial blood gas [ABG]   signs.
             ○   Noise may be heard only on inspiratory   analysis).              •  Major  errors  include  underestimating  the
               (dynamic obstruction) or during both                                 patient’s distress, overzealous exam without a
               phases (fixed obstruction).     Advanced or Confirmatory Testing     set action plan (e.g., having tools for intuba-
           •  Sometimes,  orthopneic  posture,  cyanosis,   Bronchoscopy (p. 1074), fluoroscopy, or CT   tion immediately available), and performance
             paradoxic breathing (chest and abdomen   may be useful for evaluating focal lesions and   of tests or procedures that are detrimental
             move in opposition), bulging at thoracic inlet   dynamic changes or for obtaining biopsies or   to the condition of the patient at that
             (lung lobe herniation), Horner’s syndrome   cytologic specimens.       time.
             (nasopharyngeal polyp)                                               •  A common radiographic misdiagnosis is the
           •  Hyperthermia  possible  (excessive  muscle    TREATMENT               interpretation of a prominent or mineralized
             activity, ineffective cooling)                                         (but normal) larynx as an FB, especially if
           •  Specific  conformations  (e.g.,  short  nose)   Treatment Overview    the neck is radiographed obliquely.
             raise the suspicion of associated malforma-  Minimize stress while making diagnosis;   •  Thoracic radiography and positive-pressure
             tions.                            sometimes the diagnosis and treatment occur   ventilation should be planned in case dyspnea
           •  Loud sounds may be referred to the lower   simultaneously (e.g., FB is identified and   and/or hypoxemia persist after relief of upper
             airways; auscult over the trachea  to help   removed). A general approach to treatment is   airway obstruction, as can occur when
             determine origin.                 provided on p. 1453.                 noncardiogenic pulmonary edema is also
           •  Obesity may magnify clinical signs.                                   present.
                                               Acute General Treatment            •  Dogs  may  be  presented  with  pulmonary
           Etiology and Pathophysiology        •  Sedatives  or  analgesics,  glucocorticoids   edema after a choking episode has resolved
           •  Most resistance to airflow occurs in the upper   at antiinflammatory doses, and oxygen   (e.g., “hanging” on chain).
             airways. Any fixed or dynamic obstruction   supplementation  (p.  1146)  can  be
             in the upper airways increases resistance to   lifesaving.           Prevention
             breathing  and, subsequently, the  work of   •  Secure airway patency if necessary (p. 1166).  Avoid overexertion, prevent heat stress, and
             breathing.                        •  Hyperthermia (i.e., muscle activity or ineffec-  know the medical options that are avail-
           •  Inspiration against a partially or completely   tive cooling, not true fever) can respond to   able to help break the cycle of distress and
             closed upper airway may cause noncardio-  physical cooling but not to antiinflammatory   dyspnea. Stenotic nares should be repaired
             genic pulmonary edema as the alveoli become   drugs (p. 421).        early in life.
             flooded with plasma due to negative pressure   •  Remove foreign object, if present.
             generated in the airways.                                            Technician Tips
                                               Chronic Treatment                  Minimize stress by using minimal restraint
            DIAGNOSIS                          •  Surgical  correction:  laryngeal  tie-back   and pursuing treatments in a stepwise manner.
                                                procedure, remove nasopharyngeal polyp,   Procedures  (e.g.,  catheter  placement,  blood
           Diagnostic Overview                  repair stenotic nares, and so forth  sampling,  individual  radiographs)  may  need
           Upper airway obstruction is recognized on   •  Medical management      to be staged, depending on the stability of the
           physical exam. Inspiratory dyspnea (restrictive   ○   Environmental control (e.g., avoid neck   animal. Injectable medications may be preferred
           breathing pattern characterized by a slow and   leads, avoid excessive heat)  to oral.

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