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P. 2013

1007.e2  Urachal Diverticulum




            Urachal Diverticulum
  VetBooks.ir


                                                ○   May be associated with or predispose the
            BASIC INFORMATION
                                                                                   opaque uroliths
                                                  animal  to  chronic/recurrent  UTI  and   •  Abdominal  radiographs  to  rule  out  radi-
           Definition                             urolithiasis
           Embryonic remnant at the apex of the urinary   •  Microscopic diverticulum  Advanced or Confirmatory Testing
           bladder; although diverticula occur commonly,   ○   Most common form in cats; can be   •  Contrast cystography
           they seldom result in clinical problems  identified in up to 40%        ○   Positive-contrast cystography
                                                ○   Remnants of urachus at bladder apex   ○   Double-contrast cystography
           Synonym                                that  can extend  from the  level  of  the   •  Ultrasonography
           Vesicourachal diverticulum             submucosa to the subserosa     •  Cystoscopy
                                                ○   Not associated with clinical signs  •  Exploratory celiotomy and cystotomy
           Epidemiology                       •  Acquired macroscopic diverticulum
           SPECIES, AGE, SEX                    ○   Microscopic  diverticula may become    TREATMENT
           Dogs and cats, both sexes              macroscopic  secondary to sustained
                                                  increase in bladder intraluminal pressure.  Treatment Overview
           RISK FACTORS                         ○   May spontaneously regress if the   Incidentally discovered urachal diverticula typi-
           Microscopic diverticula in cats may create risk   cause of increased bladder pressure is    cally do not require therapy. Those associated
           for developing macroscopic diverticula after   removed                with recurrent UTI or urolithiasis are surgically
           urinary tract obstruction from any cause.                             addressed.
                                               DIAGNOSIS
           ASSOCIATED DISORDERS                                                  Acute General Treatment
           •  Urinary tract infection (UTI)/bacterial cystitis  Diagnostic Overview  •  Relieve urethral obstruction if present.
           •  Urolithiasis (especially struvite)  Diagnosis of urachal diverticulum is based on   •  Fluid therapy and correction of electrolyte
           •  Feline  lower  urinary  tract  signs/disease   imaging of the urinary tract through ultrasonog-  disturbances if present
            (FLUTS/D)                         raphy, contrast urethrocystography, cystoscopy,   •  Antimicrobial therapy for bacterial cystitis
                                              or visual inspection at surgery. Often, diverticula   if present
           Clinical Presentation              are incidental findings.
           DISEASE FORMS/SUBTYPES                                                Chronic Treatment
           •  Macroscopic: intramural and extramural  Differential Diagnosis     •  Animals with clinical signs or a UTI related
           •  Microscopic                     •  Neoplasia                         to congenital macroscopic diverticula or non-
           •  Acquired macroscopic            •  Polyps                            resolving acquired macroscopic diverticula
                                              •  Urolithiasis                      should undergo surgical resection of the
           HISTORY, CHIEF COMPLAINT           •  Blood clots                       diverticulum:
           Clinical signs are often absent. When clinical                          ○   Exploratory celiotomy
           signs are apparent, they may include any of   Initial Database          ○   Ventral midline cystotomy
           the following:                     •  CBC: unremarkable                 ○   Identification of diverticulum at apex of
           •  Hematuria                       •  Serum chemistry profile: unremarkable unless   bladder
           •  Pollakiuria                       urethral obstruction exists        ○   Excision of diverticulum with elliptical
           •  Dysuria                         •  Urinalysis: often unremarkable; sometimes   incision
           •  Stranguria                        shows pyuria, hematuria, bacteruria, or   ○   Routine closure
           •  Inappropriate elimination         struvite crystalluria            •  Address chronic feline lower urinary tract
           •  Systemic illness due to urinary tract obstruc-  •  Urine culture and sensitivity (C&S) testing   signs/disease.
            tion (rare)                         is used for identifying UTI.     •  Address urolithiasis.
           PHYSICAL EXAM FINDINGS
           Physical exam is usually unremarkable. When
           present, abnormalities are nonspecific:
           •  Hematuria  (stains  on  prepuce,  vulva,  or
            hocks)
           •  Painful urinary bladder
           •  Enlarged,  turgid  bladder  with  urethral
            obstruction
           Etiology and Pathophysiology
           The  urachus  is  a  canal  connecting  the  fetal
           bladder with the allantois. The urachal lumen
           normally becomes obliterated during develop-
           ment, but on occasion the lumen remains patent
           (patent urachus) or obliteration is incomplete,
           leaving  a remnant  diverticulum.  Cause of
           incomplete urachal atrophy is unknown.  URACHAL DIVERTICULUM  Lateral radiographic projection of a double-contrast cystogram performed on a
           •  Macroscopic diverticulum        4-year-old, male, domestic short-haired cat with a history of chronic urinary tract infections. A small outpouching
            ○   Most common form in dogs      of the bladder wall is located at the apex (arrow). Diagnosis is bladder diverticulum predisposing the cat to
            ○   May not be associated with clinical signs  chronic cystitis. (Courtesy Dr. Stephanie Essman, University of Missouri.)

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