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P. 2016

Urethral Obstruction   1009


           •  Subcutaneous ureteral bypass (SUB) device   Possible Complications  •  Bilateral  ureteral  obstruction  is  rare
             (p. 1174)                         •  Renal failure (acute or chronic)  compared to unilateral obstruction but is
  VetBooks.ir  ○   A newer treatment modality that may   •  Urinary rupture and uroabdomen  •  Ureteral obstruction can recur, especially in   Diseases and   Disorders
                                               •  Postoperative ureteral stenosis
             ○   Indicated for ureteral stenosis or uretero-
                                                                                    life-threatening.
               lithiasis, primarily in cats and small dogs
                                                                                    the presence of existing nephroliths.
                                               Recommended Monitoring
               replace  other treatment  options  but is
               not without complications       •  Repeat  ultrasound  at  2  weeks  after  initial   Prevention
           •  Ureteral  stent  placed  via  interventional   evaluation and treatment, then monthly   Strategies that limit the formation of urolithiasis
             endoscopy or surgery               until resolved or stable. Remaining renal   (pp. 1014, 1016, and 1019)
             ○   Limited availability; surgery is more widely   parenchymal changes are likely permanent.
               available, which is important if the patient   •  Animals  with  permanent  hydroureter/  Technician Tips
               is unstable.                     hydronephrosis are monitored as for chronic   Animals  in  acute  renal  failure  should  have
             ○   Primarily indicated for middle-sized to   kidney disease (pp. 23 and 169). Azotemic   urine output carefully quantified. One possible
               large dogs                       animals are monitored more intensively than   correctible cause of oliguria/anuria is bilateral
           •  Ureteral surgery                  nonazotemic animals.              ureteral obstruction.
             ○   Major complication is postoperative
               ureteral stricture formation.    PROGNOSIS & OUTCOME               Client Education
             ○   Ureterotomy for intraluminal or intramu-                         Strict adherence to dietary recommendations
               ral obstruction in the proximal third of   •  Depends on underlying cause, duration of   can minimize the risk of ureteral or urethral
               the ureter                       obstruction, extent of renal parenchymal   obstruction due to urolithiasis.
             ○   Ureteroneocystostomy for resection of   damage, presence of concurrent infection,
               distal ureter                    and ability to resolve underlying cause  SUGGESTED READING
             ○   Ureteroureterostomy to repair ureter after   •  Structural renal changes persisting 14-45 days   Berent A, et al: Subcutaneous ureteral bypass device
               resection or transection (anastomosis of   or more after relief of ureteral obstruction   placement for benign ureteral obstruction in cats:
               proximal ureter to distal portion of ureter   are generally permanent.  137 cats (174 ureters). J Vet Intern Med 30:1539-
               on ipsilateral side), usually when proxi-  •  Complete bilateral obstruction of more than   1540, 2016.
               mal third cannot be implanted directly   3 days is fatal without appropriate treatment.  AUTHOR: Adam Mordecai, DVM, MS, DACVIM
               into bladder neck; highest incidence of                            EDITOR: Leah A. Cohn, DVM, PhD, DACVIM
               postoperative obstruction        PEARLS & CONSIDERATIONS
           •  Nephrectomy is reserved for animals with
             unilateral obstruction, adequate function in   Comments
             contralateral kidney, and loss of virtually all   •  Ureteral obstruction should be considered
             function in the affected kidney.   in the differential diagnosis for renal failure,
                                                especially  in patients  with  evidence  of
           Nutrition/Diet                       nephrolithiasis or pyelonephritis.
           Diet appropriate for preventing specific urolith
           type





            Urethral Obstruction                                                                   Client Education
                                                                                                          Sheet


            BASIC INFORMATION                  •  Neoplasia                       PHYSICAL EXAM FINDINGS
                                               •  Urinary tract infection         •  Enlarged, turgid urinary bladder (characteristic)
           Definition                          •  Risk factors associated with urolithiasis (pp.   •  Abdominal discomfort (common)
           The common condition involves obstruction   1014, 1016, and 1019)      •  Dribbling urine (occasionally)
           of the lower urinary tract and is usually due to                       •  Bloody preputial/vulvar discharge (occasion-
           urolith or matrix formation. Other causes (e.g.,   ASSOCIATED DISORDERS  ally)
           neoplasia, stricture, infections) are less common.  •  Hydronephrosis  •  Palpable urethral urolith or tumor (digital
                                               •  Azotemia/uremia                   rectal exam in dogs) (occasionally)
           Epidemiology                        •  Hyperkalemic cardiac dysrhythmia  •  Bradycardia if severe hyperkalemia (in very
           SPECIES, AGE, SEX                   •  Urinary bladder rupture           advanced cases)
           •  Cats and less commonly dogs of any age  •  Bladder atonia/hypotonia
           •  Males  are  anatomically  predisposed  to   •  Urinary tract infection  Etiology and Pathophysiology
             obstruction.                      •  Postobstructive diuresis        •  Urine supersaturation, urinary tract infection,
                                                                                    certain disease states, and breed predisposi-
           GENETICS, BREED PREDISPOSITION      Clinical Presentation                tion contribute to urolithiasis.
           •  Certain breeds predisposed to specific urolith   HISTORY, CHIEF COMPLAINT  •  In  cats  especially,  urethral  plugs  may  be
             formation (e.g., Dalmatians: urate uroliths)  •  Urinary  tract  signs:  pollakiuria,  dysuria,   composed of matrix (cellular debris, virus-like
           •  Other breeds predisposed to urethral neo-  stranguria, anuria/oliguria, hematuria, drib-  particles, ± bacteria, urinary crystals).
             plasia (e.g., Scottish terrier)    bling urine, licking prepuce/vulva (urethral   •  Uroliths or plugs can obstruct the urethra;
                                                discharge)                          urethral anatomy favors obstruction in males.
           RISK FACTORS                        •  Systemic signs: lethargy, anorexia, vocaliza-  •  Neoplasia, especially transitional cell carcinoma
           •  Feline  lower  urinary  tract  signs/disease   tion, restlessness, weakness, discomfort  (p. 991), may progress to cause obstruction.
             (FLUTS/D) (p. 332)                •  History of urinary infection or urolithiasis  •  Urethritis may lead to urethral stricture.

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