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Uterine Disorders, Non-neoplastic   1021




            Uterine Disorders, Non-neoplastic                                                      Client Education
                                                                                                          Sheet
  VetBooks.ir                                                                                                         Diseases and   Disorders

                                               •  ± Collapse
            BASIC INFORMATION
                                               •  ± Devitalized prolapsed tissue    ishemic), cesarean section to deliver remain-
                                                                                    ing fetuses if still viable, or ovariohysterec-
           Definition                                                               tomy (OHE) if tissue is devitalized
           •  Uterine torsion is an uncommon condition   Etiology and Pathophysiology  •  Prolapsed  tissue  is  cleaned  and  replaced
             involving twisting of one or both uterine   •  Torsion:  unknown  cause;  may  be  due  to   with combination of manual manipula-
             horns or the uterine body on its own axis.  fetal or bitch activity or abnormal uterine   tion  externally  and  abdominal  surgical
           •  Uterine prolapse is a rare condition where the   motility (inertia) with continued fetal activ-  approach. OHE may be necessary if tissue is
             uterus everts through the cervix and vagina   ity; pyometra, mucometra, hydrometra, or   devitalized.
             (one or both horns may be involved).  hematometra; neoplasia
                                               •  Prolapse: eversion of the tip of a uterine horn   Acute General Treatment
           Epidemiology                         followed by excessive straining (due to any   Torsion:
           SPECIES, AGE, SEX                    cause) during uterine involution or eversion   •  Broad-spectrum  antibiotics  (ampicillin
           Either condition may occur at any age or   of the tip of a horn due to uterine inertia   10-22 mg/kg IV q 6-8h with enrofloxacin
           parity. Uterine torsion may occur unrelated   followed by normal uterine contraction   10-15 mg/kg  IM,  SQ,  or  IV  q  24h;
           to pregnancy. Prolapse is more common in    patterns                     maximum of 5 mg/kg q 24h IM in cats) as
           queens.                                                                  soon as diagnosis is confirmed and when
                                                DIAGNOSIS                           devitalized tissue is present
           RISK FACTORS                                                           •  If the horn is severely ischemic or necrotic,
           •  Large litter size may predispose to torsion.  Diagnostic Overview     do not detorse the affected horn(s) because
           •  Any  condition  causing  excessive  straining   •  Torsion: based on cessation of labor or acute   this may result in reperfusion injury and
             (e.g., dystocia, necrotic vaginitis, severe cys-  abdominal  pain. Ultrasound may  be sup-  allow systemic circulation of bacteria
             titis, diarrhea, constipation) may predispose   portive, but diagnosis is conclusively based   and toxin; perform OHE with torsion
             to prolapse.                       on exploratory laparotomy.          in situ.
                                               •  Prolapse: based on physical exam findings   •  If only one horn is affected, partial OHE
           ASSOCIATED DISORDERS                 of prolapsed tissue from the vulvar lips   may be performed, oversewing the uterine
           Both may be associated with shock, sepsis,   after parturition. Inability to locate the   body at the level of the bifurcation.
           disseminated intravascular coagulation, multiple   uterus on ultrasound of the abdomen is     Prolapse:
           organ dysfunction syndrome, and systemic   confirmatory.               •  Initially, digital pressure and inversion of the
           inflammatory response syndrome.                                          horn into itself starting distally and working
                                               Differential Diagnosis               toward the tip. Applying 50% dextrose solu-
           Clinical Presentation               Uterine torsion:                     tion topically and waiting a few minutes for
           DISEASE FORMS/SUBTYPES              •  Pyometra                          osmotic detumescence may decrease size of
           •  Torsion may involve one or both horns and/  •  Uterine rupture        prolapsed tissue.
             or the uterine body and may be from 90°   •  Uterine inertia (primary or secondary)  •  Care should be taken to invert the entire
             to >2160° (six complete turns described in   •  Acute gastrointestinal disorders (bloat, gastric   horn to its tip (this should be confirmed
             one report).                       or mesenteric torsion), other causes of the   visually).
           •  Prolapse occurs in the puerperal period and   acute abdomen         •  Oxytocin after complete inversion for uterine
             may involve one or both horns, be partial or   Uterine prolapse:       involution
             complete, and occurs rarely before delivery   •  Bladder or vaginal prolapse  •  If manual reduction is impossible, uterine
             of all fetuses.                   •  Vaginal rupture and evisceration  amputation is indicated.
                                               •  Vaginal, cervical, or uterine neoplasia
           HISTORY, CHIEF COMPLAINT                                               Behavior/Exercise
           Torsion:                            Initial Database                   If the dam is stable, she may be allowed to
           •  History of no progression from stage 1 to   •  CBC: ± leukocytosis, ± toxic neutrophils,   nurse any neonates.
             stage 2 of labor or cessation of ongoing stage   evidence of dehydration
             2 labor                           •  Serum  biochemistry  profile:  normal  to   Recommended Monitoring
           •  Acute abdominal pain              increased renal and hepatic values and   CBC, serum biochemistry profile
           •  Shock                             electrolyte disturbance, depending on
           Prolapse:                            duration                           PROGNOSIS & OUTCOME
           •  History  of  prolonged  straining  (labor,     •  Abdominal ultrasonography
             other)                             ○   Hemorrhage into uterine lumen and   •  With early diagnosis, the prognosis is good
           •  Tissue protrudes from the vulvar lips.  edema (hypoechogenicity) of the uterine   for survival.
           •  Queens may present up to 48 hours after   wall adjacent to the torsion  •  With  systemic  illness,  the  prognosis  for
             delivery of last kitten.           ○   Fetuses may be viable or dead.  survival is guarded to poor.
                                                ○   Intraluminal gas may be present.  •  Recurrence is unlikely.
           PHYSICAL EXAM FINDINGS
           •  Acute abdominal pain and splinting   TREATMENT                       PEARLS & CONSIDERATIONS
           •  Vocalization
           •  Hemorrhagic vulvar discharge     Treatment Overview                 Comments
           •  Excessively vulvar licking       Treatment goals:                   •  Caution  should  be  taken  when  handling
           •  Abdominal distention             •  Patient stabilization (IV fluid resuscitation,   either condition because the uterine wall
           •  Tachycardia and tachypnea         pain control)                       may be friable.
           •  Pale  mucous  membranes  with  increased   •  Exploratory  laparotomy  for  correction  of   •  Do not administer calcium or oxytocin to
             capillary refill time              torsion (if tissue is not necrotic or severely   patients suspected of torsion or prolapse.
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