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1028  Vaginal Hyperplasia and Vaginal Prolapse


           •  Inadequate resection does not resolve clinical   ○   The diameter of the vestibulovaginal   Client Education
            signs.                                junction must be less than 30% of the   •  Breeding  bitches  that  are  reluctant  to
  VetBooks.ir  Recommended Monitoring         •  Most  congenital  vaginal  abnormalities  do   •  Congenital vaginal anomalies may be present
                                                  diameter of the maximal diameter of the
                                                                                   stand for a male may have vestibulovaginal
                                                  vagina to be considered pathologic.
                                                                                   abnormalities that cause painful breeding.
           Observe the animal for recurrence of signs.
           Initial  treatment  may  have  to  be  repeated
                                                not cause clinical signs.
           if stricture occurs secondary to resection or   •  Vestibulovaginal  abnormalities  (parame-  without causing clinical signs.
           traumatic dilation.                  sonephric septal remnants, vaginal septa,   SUGGESTED READING
                                                double vagina) are very common in dogs   Crawford JT, et al: Influence of vestibulovaginal
            PROGNOSIS & OUTCOME                 with ectopic ureters.              stenosis, pelvic bladder, and recessed vulva on
                                                                                   response to treatment for clinical signs of lower
           •  Prognosis is good if clinical signs are caused   Prevention          urinary tract disease in dogs: 38 cases (1990-1999).
            by hymenal remnants or mild vaginal   Because  most  vestibulovaginal  abnormalities   J Am Vet Med Assoc 221:995-999, 2002.
            stricture.                        are congenital but not hereditary, there are   AUTHOR: James A. Flanders, DVM, DACVS
           •  Prognosis for resolution of clinical signs is fair   no recommendations against breeding affected   EDITOR: Michelle A. Kutzler, DVM, PhD, DACT
            to good for severe vaginal stricture treated by   bitches after the abnormality is treated.
            vestibulovaginal resection and anastomosis.
                                              Technician Tips
            PEARLS & CONSIDERATIONS           Although digital vaginal exam is helpful
                                              in making a diagnosis of vestibulovaginal
           Comments                           abnormality, direct visual inspection using
           •  Do  not  confuse  normal  narrowing  at  the   vaginoscopy permits a much more accurate
            vestibulovaginal junction with a pathologic   diagnosis.
            condition.







            Vaginal Hyperplasia and Vaginal Prolapse                                               Client Education
                                                                                                         Sheet


            BASIC INFORMATION                 ASSOCIATED DISORDERS               PHYSICAL EXAM FINDINGS
                                              Markedly  prolapsed  vaginal  tissue  is  subject   Bulge at the perineum or protrusion of a pink,
           Definition                         to self-mutilation and may be dry, ulcerated,   dome- or doughnut-shaped mass from vulva;
           Edematous swelling of the vaginal mucosa   necrotic, and devascularized; possible dysuria   surface of protrusion may be dry, necrotic, or
           cranial to the urethral orifice is an uncommon   or pollakiuria       ulcerated. Vaginal exam reveals:
           disorder that occurs during estrogen stimulation   Clinical Presentation  •  A urethral orifice located ventrally in all three
           in the intact bitch. It may progress to vaginal                         types of vaginal hyperplasia
           protrusion through the vulvar lips.  DISEASE FORMS/SUBTYPES           •  Vaginal lumen is located dorsally in types I
                                              Vaginal hyperplasia:                 and II but centrally located in type III.
           Synonyms                           •  Type I: slight to moderate eversion of the   •  In contrast, uterine prolapse is distinguished
           Vaginal edema, hypertrophy, hyperplasia,   vaginal floor cranial to the urethral orifice;   by the presence of tubular masses in the
           eversion, or protrusion              confined to the vestibulum and appearing   vagina or protruding from the vulva.
                                                as a bulge at the perineum
           Epidemiology                       •  Type  II:  well-developed  swelling  of  the   Etiology and Pathophysiology
           SPECIES, AGE, SEX                    vaginal floor, which may include the lateral   •  An  exaggerated  response  of  the  vaginal
           Intact bitch, 7 months to 16 years old  vaginal walls, and protruding through the   mucosa to estrogen (hyperemia, edema,
                                                vulvar  lips. The swelling appears  dome   keratinization), the swelling begins as an
           GENETICS, BREED PREDISPOSITION       shaped.                            eversion in the vaginal floor, cranial to the
           •  More common in large-breed dogs  •  Type  III:  well-developed  protrusion  of   urethral orifice.
           •  Predisposed breeds: bulldog, mastiff, boxer,   the entire circumference of the vaginal   •  Histopathologic  exam  of  affected  vaginal
            Dalmatian, German shepherd, Saint Bernard,   wall through the vulvar lips. The swelling   tissue is consistent with submucosal edema
            Labrador  and  Chesapeake  Bay  retrievers,   appears doughnut-shaped and is a vaginal    rather than hyperplasia or hypertrophy.
            Weimaraner, Walker hound, springer spaniel,   prolapse.
            Airedale terrier, and American pit bull                               DIAGNOSIS
            terrier                           HISTORY, CHIEF COMPLAINT
           •  One case report of type III vaginal prolapse   •  Previous occurrence of vaginal hyperplasia  Diagnostic Overview
            in a pregnant Maine coon cat      •  Onset of proestrus or estrus    The diagnosis is suspected based on the presence
                                              •  Licking or irritation of the vulva  of a vulvar swelling or protrusion in a young
           RISK FACTORS                       •  Mass protruding from vulva or bulge at the   intact bitch. Typically, condition occurs during
           •  Young bitch under the influence of estrogen   perineum             one of the first three estrous cycles.
            during proestrus or estrus; may occur or recur   •  Dysuria or pollakiuria
            during diestrus, pregnancy, or parturition  •  Failure  to  allow  intromission  during    Differential Diagnosis
           •  Can  be  observed  as  side  effect  of  estrus   breeding         •  Benign or malignant vaginal neoplasia
            induction with estrogen           •  Tenesmus                        •  Vaginal polyp or cyst

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