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Vasculopathy, Cutaneous   1031


                                                                                  •  In mild to moderate cases of juvenile vagi-
                                                                                    nitis, twice-daily cleaning with baby wipes
  VetBooks.ir                                                                     Possible Complications              Diseases and   Disorders
                                                                                    may be beneficial.

                                                                                  •  Ascending  UTI  can  result  from  chronic
                                                                                    vaginitis.
                                                                                  •  Self-mutilation  can  result  from  excessive
                                                                                    licking of the perivulvar skin secondary to
                                                                                    vaginitis.
                                                                                  Recommended Monitoring
                                                                                  Recheck animals showing any signs of systemic
                                                                                  illness, and look for complications such as
            A                               B                                     metritis.
           VAGINITIS  A, Vaginoscopy of a bitch with chronic vaginitis shows prominent lymphoid follicles on the vaginal    PROGNOSIS & OUTCOME
           mucosa. B, Vaginoscopy of a bitch presenting with vaginitis shows a grass awn in the vaginal lumen. (Courtesy
           Dr. Autumn Davidson.)                                                  •  With spontaneous remission, future repro-
                                                                                    ductive success is not compromised.
           •  Contrast radiography                5 days, tapering to 2 times per week, or   •  In prepubertal dogs, vaginitis may or may
           •  Biopsy                              phenylpropanolamine 1-1.5 mg/kg PO q   not resolve after one or more estrous cycles,
                                                  8-12h (p. 1011)                   but ovariohysterectomy should be delayed
            TREATMENT                           ○   In overweight dogs with urinary inconti-  until after the first cycle.
                                                  nence with excessive perivulvar skin folds,
           Treatment Overview                     persistent moisture, and urine scalding,    PEARLS & CONSIDERATIONS
           •  Without an identifiable underlying primary   vulvoplasty (episioplasty) is recommended.
             cause, most cases of juvenile-onset and adult-  ○   Vaginal anatomic anomalies (up to   Comments
             onset vaginitis resolve spontaneously.  36%  of  cases):  surgical  repair  may  be    Limited understanding of the causes of vaginitis
             ○   Treatment of the underlying cause, if   indicated.               makes it difficult to predict when and if clinical
               identified, is usually curative.  •  If the primary problem is idiopathic  signs will resolve.
           •  Most therapy for vaginitis is symptomatic   ○   DES may be helpful to treat subclinical
             because most cases are idiopathic.   urinary  incontinence  and  may  enhance   Technician Tips
                                                  WBC migration to the vagina and increase   Excessive licking may be prevented using an
           Acute General Treatment                vaginal elasticity. NOTE: do not use DES   Elizabethan  collar;  sedation  (e.g.,  trazodone
           •  In juvenile-onset and adult-onset vaginitis,   in dogs that have not reached full height   2-3 mg/kg PO q 24h) may reduce scooting.
             antibiotic treatment, if used, should be   because it may induce premature physeal
             based on results of culture and sensitivity   closure of the long bones.  Client Education
             (cranial vaginal guarded sample) and given   ○   Glucocorticoids may be beneficial in some   Daily record of the frequency and severity of
             for 4 weeks. Antibiotics are usually not war-  bitches. Do not use in cases of concurrent   clinical signs (e.g., vulvar discharge, vulvar
             ranted for mixed bacterial growth (a normal   urinary incontinence.  licking)  can  help  the  veterinarian  to  assess
             finding).                         •  If  history  or  clinical  signs  of  concurrent   response to therapy.
           •  Vaginal douches with antiseptics or antibiot-  atopic dermatitis (p. 91) and vaginitis coexist
             ics are unrewarding.               ○   May  be  beneficial  to  use  hydroxyzine   SUGGESTED READING
           •  If the primary problem is urinary inconti-  1-2 mg/kg PO q 8-12h; decrease the dose   Root Kustritz MV:  Vaginitis in dogs: a simple
             nence                                if  treatment  is  effective  or  if  secondary   approach  to  a complex  condition.  Vet Med
             ○   Urinary incontinence suspected due to   effects such as sedation are pronounced  103:562-567, 2008.
               urethral sphincter  mechanism incom-                               AUTHOR: Carlos M. Gradil, DVM, MS, PhD, DACT
               petence  (up  to  60%  of  adult  cases):   Chronic Treatment      EDITOR: Michelle A. Kutzler, DVM, PhD, DACT
               diethylstilbestrol (DES) 0.1-0.2 mg/kg,   •  Owners  should  be  instructed  to  keep  the
               maximum dose of 1 mg PO q 24h for   perivulvar skin folds clean.






            Vasculopathy, Cutaneous                                                   Bonus Material   Client Education
                                                                                           Online
                                                                                                          Sheet
                                               Epidemiology
            BASIC INFORMATION                                                     •  Familial cutaneous vasculopathy (autosomal
                                               SPECIES, AGE, SEX                    recessive): Parson (Jack) Russell terrier, Scot-
           Definition                          Dogs and cats of any  age and either sex;   tish terrier, German shepherd
           The condition is characterized by blood   dermatomyositis becomes manifest in young   •  Alabama rot: greyhounds
           vessel abnormalities that result in tissue   dogs (usually < 6 months)  •  Proliferative thrombovascular necrosis of the
           necrosis. It can be divided into ischemic                                pinnae: dachshund, Weimaraner
           dermatopathies and cutaneous vasculitis   GENETICS, BREED PREDISPOSITION  •  Rabies  vaccine  injection-site  vasculitis
           (inflammatory process that targets the blood     Any breed, but certain syndromes show breed   (p.  550):  miniature  poodle,  Bichon  frisé,
           vessels).                           predisposition:                      Yorkshire terrier
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