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Viral Respiratory Disease 1039.e3


           •  Viral isolation is the gold standard but rarely   •  Feeding tubes (nasoesophageal for short-term   Client Education
             performed.                         feeding)                          •  Follow recommended vaccination schedules,
  VetBooks.ir  presentation.                   Possible Complications             •  Close  contact  with  pets  while  the  owner   Diseases and   Disorders
                                                                                    especially if boarding or other animal expo-
           •  Other  diagnostics  vary  by  clinical
                                                                                    sures are likely.
             ○   Conjunctival scrape (e.g., confirm CDV;
                                               •  Pneumonia
               rule out C. felis)
             ○   Serologic  titers  (e.g.,  confirm  CDV,   •  Chronic corneal cultures (FHV)  suffers influenza should be avoided to further
                                               •  Chronic gingivostomatitis (FCV)
                                                                                    reduce the very small risk of interspecies
               influenza; rule out  Cryptococcus); must   •  Chronic sequela related to CDV (p. 271)  transmission.
               consider vaccine status when antibody
               titers performed                 PROGNOSIS & OUTCOME               SUGGESTED READING
                                                                                  Lappin MR, et al: Antimicrobial use guidelines for
            TREATMENT                          Viral upper respiratory infections are typically   treatment of respiratory tract disease in dogs and
                                               self-limited and have a good prognosis for   cats: Antimicrobial Guidelines Working Group of
           Treatment Overview                  complete recovery. Some feline upper respira-  the International Society for Companion Animal
           Treatment is generally supportive. Isolation   tory viral infections (FHV, FCV) can lead to   Infectious Diseases. J Vet Intern Med 31:279, 2017.
           from other dogs/cats is important to prevent   chronic complications that may be difficult to
           disease transmission from the patient to unin-  control or may be associated with intermittent   ADDITIONAL SUGGESTED
           fected animals and to prevent transmission of   disease relapses. Viral pneumonia or bacterial   READINGS
           additional pathogens to the debilitated patient.   pneumonia secondary to viral infection carries   Ballin AC, et al: Limited efficacy of topical recom-
           Unless pneumonia necessitates hospitalization,   a more guarded prognosis but many animals   binant feline interferon-omega for treatment of
           outpatient treatment is preferred.  recover completely. The prognosis is worse for   cats with acute upper respiratory viral disease. Vet
                                               CDV (guarded) and FIP (grave).      J 202:466, 2014.
           Acute General Treatment                                                Litster A, et al: Detection of feline upper respira-
           Dogs:                                PEARLS & CONSIDERATIONS            tory tract disease pathogens using a commercially
                                                                                   available real-time PCR test. Vet J 206:149, 2015.
           •  If cough is severe and nonproductive with                           McManus CM, et al: Prevalence of upper respira-
             no evidence of pneumonia, consider cough   Comments                   tory pathogens in four management models for
             suppressants.                     •  In an outbreak investigation, sample at least   unowned cats in the Southeast United States. Vet
           •  Secondary  bacterial  pneumonia  requires   3-5 animals as early in the disease course as   J 201:196, 2014.
             antimicrobial therapy ideally guided by   possible; necropsy any animals that succumb.  Parrish  CR,  et  al:  Influenza  virus  reservoirs  and
             culture and sensitivity (p. 795).  •  Vaccination  against  respiratory  pathogens   intermediate hosts: dogs, horses, and new pos-
           •  If B. bronchiseptica or M. cynos co-infection   may reduce severity of disease caused by   sibilities for influenza virus exposure of humans.
             is deemed likely, doxycycline 5 mg/kg PO   unrelated respiratory pathogens, likely by   J Virol 89:2990, 2015.
             q 12h or 10 mg/kg PO q 24h may be con-  reducing multiple pathogen infections.  Priestnall SL, et al: New and emerging pathogens
                                                                                   in canine infectious respiratory disease. Vet Pathol
             sidered. However, antibiotics do not address   •  No role has been demonstrated for steroids   51:492, 2014.
             viral infection, and indiscriminant use may   for most viral respiratory infections (FIP   Schulz  BS,  et  al:  Detection  of  respiratory  viruses
             promote antimicrobial drug resistance.  pneumonia is an exception)    and  Bordetella bronchiseptica in dogs with acute
           Cats:                               •  Antiinfluenza  drugs  (e.g.,  oseltamivir)  are   respiratory tract infections. Vet J 201:365, 2014.
           •  Airway humidification and nebulization  not indicated in pets.      Schulz C, et al: Sampling sites for detection of feline
           •  Topical and systemic antiviral drugs for FHV   •  Virulent  systemic  FCV  can  cause  life-  herpesvirus-1, feline calicivirus and Chlamydia felis
             ocular disease (see relevant chapters)  threatening vasculitis but is rare (p. 141).  in cats with feline upper respiratory tract disease.
           •  If  fever,  lethargy,  or  anorexia  accompany                       J Feline Med Surg 17:1012, 2015.
             substantial mucopurulent nasal discharge   Prevention
             suggestive  of  secondary  bacterial  rhinitis,   •  Maintain excellent air quality and sanitation   RELATED CLIENT EDUCATION
             antibiotics may be used (doxycycline 5 mg/kg   in crowded animal facilities such as shelters   SHEETS
             PO q 12h or 10 mg/kg PO q 24h; amoxicil-  and kennels
             lin 22 mg/kg PO q 12h)            •  Isolate  animals  demonstrating  respiratory   Canine Infectious Respiratory Disease Complex
           Both species:                        signs from other animals.           (Kennel Cough)
           •  Excellent  nursing  care,  including  clearing   •  Vaccines  exist  for  many  viral  respiratory   Consent to Administer Vaccinations, Canine
             nasal/ocular secretions            pathogens.                        Consent to Administer Vaccinations, Feline
           •  Ensure adequate oxygenation if pneumonia   ○   Dogs: CDV (core), CAV-2 (core), cPIV   Consent to Perform Bronchoalveolar Lavage
             present.                             (conditional), influenza virus (conditional)  (BAL)
           •  Ensure adequate hydration using SQ or IV   ○   Cats: FHV (core), FCV (core)  Feline Infectious Peritonitis
             fluids if needed.                                                    Pneumonia
                                               Technician Tips
           Chronic Treatment                   Ask pet owners about potential exposure to   AUTHOR: Leah A. Cohn, DVM, PhD, DACVIM
           Chronic ocular disease related to FHV may   other dogs/cats in the weeks before onset of   EDITOR: Megan Grobman, DVM, MS, DACVIM
           require long-term therapy (pp. 208 and 464).  respiratory signs.

           Nutrition/Diet
           Ensure adequate nutrition.
           •  Enticing (warmed, moist) foods
           •  Appetite stimulants (e.g., mirtazapine)








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