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Vitamin A Toxicosis 1039.e5


            PROGNOSIS & OUTCOME                •  Vitamin A is fat soluble; 90% is stored in   ADDITIONAL SUGGESTED
                                                the liver and 10% in adipose tissue.  READINGS
  VetBooks.ir  •  Chronic: guarded prognosis; bony changes   Prevention           Puls R: Vitamin A in dogs, vitamin A in cats. In Puls   Diseases and   Disorders
           •  Excellent in acute cases
                                                                                   R: Vitamin levels in animal health: diagnostic data
             are permanent, and some cats that were fed
                                               Do not overfeed raw beef liver to cats.
                                                                                   and bibliographies, Clearbrook, British Columbia,
             only liver may refuse to eat anything else.
                                                                                   1994, Sherpa International, pp 14, 20.
                                               Technician Tips                    Rader JD: Vitamin A. In Plumlee K, editor: Clinical
            PEARLS & CONSIDERATIONS            In cats, lameness, weight loss, and stiff ven-  veterinary toxicology, St. Louis, 2003, Mosby, p
                                               troflexion of neck should prompt question-  330.
           Comments                            ing about cat’s diet (raw liver in the diet or   Vitamin  deficiencies  and  excesses.  In  Case  LP,  et
           •  Vitamin A deficiency is far more common   supplementation with cod liver oil).  al, editors: Canine and feline nutrition, ed 2, St.
             than intoxication.                                                    Louis, 2000, Mosby, pp 345-350.
           •  Dogs can convert beta-carotene into vitamin   Client Education      Vitamins. In Case LP, et al, editors: Canine and
                                                                                   feline nutrition: a resource for companion animal
             A, but cats cannot.               Teach owners the value of a balanced diet.  professionals, ed 3, St. Louis, 2011, Mosby.
           •  The amount of vitamin A needed to cause
             toxic  effects  is  usually  10-1000  times  the   SUGGESTED READING  AUTHOR: Safdar A. Khan, DVM, MS, PhD, DABVT
             dietary requirements for most species for   Khan SA: Vitamin A toxicosis. In The Merck Manual   EDITOR: Tina Wismer, DVM, MS, DABVT, DABT
             several months.                    Veterinary Manual, Kenilworth, NJ, 2016, Merck
           •  The  vitamin  A  requirement  for  cats  is   & Co., Inc. (website). http://www.merckvetmanual.
             10,000 IU/kg of diet fed, with levels up to   com/toxicology/toxicities-from-human-drugs/
             100,000 IU/kg of diet tolerated.   multivitamins-and-iron-toxicity
           •  For dogs, the requirement is 3333 IU/kg of
             diet fed, with up to 33,330 IU/kg of diet
             tolerated.
























































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