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1134.e2  Myelography


            of temporalis muscle, make sure that the   •  Proprioceptive deficits as already described;   ADDITIONAL SUGGESTED
            frontalis muscle is not collected by mistake.  usually self-resolving in 3-4 days; long-term   READING
  VetBooks.ir  mended for routine muscle biopsy collection   Alternatives and Their Relative   Melmed C, et al: Masticatory muscle myositis:
                                                deficits are extremely uncommon
           Percutaneous needle/core biopsy is not recom-
                                                                                   pathogenesis, diagnosis, and treatment. Compend
           in dogs and cats:
                                                                                   Contin Educ Pract Vet 26:590-605, 2004.
                                              Merits
           •  Inadequate sample size
           •  Difficult to orient tissue      •  For muscle diseases, there is no alternative   Reproduced from the third edition in
           •  Artifact                          to the muscle biopsy for determining the   unabridged form.
           Needle/core biopsies may be beneficial in research   specific diagnosis and therapeutic options.
           situations  where  sequential  biopsy  samples   •  MRI studies may help localize focal lesions   RELATED CLIENT EDUCATION
           may be required over time; may be guided by   and allow guided muscle biopsies.  SHEET
           ultrasonographic localization of specific lesions.  •  Electrophysiologic examinations can provide
                                                important information on peripheral nerve   Consent to Perform General Anesthesia
           Postprocedure                        diseases, but a peripheral nerve biopsy should
           •  Treatment  of  hemorrhage,  swelling,  or   be collected for histologic evaluation.  AUTHOR: G. Diane Shelton, DVM, PhD, DACVIM
            hematoma if these occur (rare)                                       EDITORS: Leah A. Cohn, DVM, PhD, DACVIM; Mark S.
           •  External dressings are not normally required.  SUGGESTED READING   Thompson, DVM, DABVP
           •  Animals  should  be  monitored  to  prevent   Dickinson PJ, et al: Muscle and nerve biopsy. Vet
            interference with the sutures.     Clin North Am Small Anim Pract 32:63-102, 2002.




            Myelography                                                                            Client Education
                                                                                                         Sheet


           Difficulty level: ♦♦                 iohexol or iopamidol (180-300 mg iodine/  •  Bradycardia  is  sometimes  seen  in  animals
                                                mL most commonly used)             during injection of the contrast material.
           Overview and Goal                    ○   Full spine dosage is 0.45 mL/kg; regional   •  Epidural injection may occur with lumbar
           Myelography is the introduction of nonionic   dosage is 0.3 mL/kg.      puncture.
           positive-contrast media into the subarachnoid   •  A 20- to 22-gauge spinal needle with stylet   •  Subdural injection may result in central canal
           space. It is used for demonstrating lesions in   and short bevel, 1 2  to  3 2  inches (depend-  filling.
                                                            1
                                                                 1
           the spinal cord or lesions extrinsic to the spinal   ing on size of animal)  •  Administration of air bubbles
           cord that may be causing cord compression.  •  Appropriately sized syringe (3-35 mL)  •  Use of the incorrect type of contrast agent
                                              •  Flexible extension tubing or T-port (catheter   can  be  fatal.  Ionic  contrast  agents  should
           Indications                          cap with side line and port)       never be used in any amount in myelography;
           •  Clinical signs of spinal cord disease (± spinal   •  Hair clippers   only low-osmolar, nonionic, water-soluble
            trauma) when magnetic resonance imaging   •  Surgical scrub solution, rubbing alcohol, and   iodine agents are indicated.
            (MRI) is not an option              gauze/sponge for prepping skin   •  Lumbar puncture: inability to enter the space
           •  Spinal pain or neurologic deficits without   •  Sterile surgical gloves  is commonly due to a non-midline location
            diagnosis on plain films or laboratory tests                           of the needle (needle is inadvertently located
           •  Confirmation of suspected lesion on plain   Anticipated Time         parallel and lateral to dorsal midline).
            films                             About 45-60 minutes, not including prepro-  •  Extension  of  the  neck  for  neck-extended
           •  Aid in surgical planning (define exact location   cedural anesthesia time  views  can  cause  permanent  cord  injury,
            of lesion)                                                             especially in animals with neck pain before
           •  Determine amount of spinal cord swelling  Preparation: Important     the procedure and animals with severe cervi-
           •  Exclude compressive lesions of the spinal cord;   Checkpoints        cal intervertebral disc disease (IVDD). These
            by process of elimination, make presumptive   •  CSF analysis to ensure no evidence of infec-  views should be preceded by nonextended
            diagnosis of noncompressive spinal disorder  tion or inflammation      views (diagnosis may be apparent without
           •  Rule out intraspinal lesion     •  Ensure adequate hydration status to decrease   extension) or avoided altogether.
           •  Disparity between clinical signs and plain   risk of neurotoxicosis; IV fluids as appropriate
            radiographs                       •  Metastasis  imaging  (three-view  thoracic   Procedure
           •  Recurrence of clinical signs after decompres-  radiographs are also indicated if malignancy   •  Obtain  survey  radiographs  of  the  area  of
            sive spinal surgery                 is part of the differential diagnosis for the   interest (ventrodorsal and lateral views).
                                                spinal problem)                  •  Clip a large area of hair near the injection site
           Contraindications                  •  Advise owner the hair will be clipped in a   (depending on cisternal or lumbar puncture).
           •  Cerebrospinal fluid (CSF) analysis indicates   large area near the injection site(s).  •  Aseptically prepare the site for injection with
            inflammation or infection: condition aggra-                            surgical  scrub  solution,  isopropyl  alcohol,
            vated by irritation from contrast medium  Possible Complications and   and gauze/sponges.
           •  Increased CSF pressure: possible herniation   Common Errors to Avoid  •  Sterile surgical gloves should be worn from
            of cerebellum through foramen magnum  •  The most common complication of myelog-  this point on, and a sterile technique should
           •  Known hypersensitivity to contrast medium  raphy is postprocedure seizures. Recover the   be  used  (nonsterile  materials  need  to  be
                                                animal with head elevated to minimize risk.   handled by an assistant).
           Equipment, Anesthesia                If directly induced by contrast, seizures are   •  Draw correct contrast dose into syringe.
           •  General anesthesia                expected to occur during anesthetic recovery.   •  Attach  flexible  extension  tubing  to  the
           •  Intrathecal contrast material: low osmolar,   Seizures  occurring  thereafter  are  virtually   syringe, and fill with contrast so no air
            nonionic,  water-soluble  iodines,  such  as   never caused by the contrast injection.  bubbles are present.

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